Volume 10, Issue 3 (11-1996)                   Med J Islam Repub Iran 1996 | Back to browse issues page

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NIKNAFS P, SOTUDEHNEJAD A, TABRIZCHI H. PRACTICAL PROBLEMS AND THE EFFICACY OF INTRAOSSEOUS INFUSION: SOLVING THE PROBLEMS BY EMPLOYING AN ANIMAL MODEL. Med J Islam Repub Iran 1996; 10 (3) :229-232
URL: http://mjiri.iums.ac.ir/article-1-1188-en.html
PRACTICAL PROBLEMS AND THE EFFICACY OF INTRAOSSEOUS INFUSION: SOLVING THE PROBLEMS BY EMPLOYING AN ANIMAL MODEL
PEDRAM NIKNAFS , ALlREZA SOTUDEHNEJAD , HAMID TABRIZCHI
From the Departments of Pediatrics Kerman University of Medical Sciences and Health Services, Kerman, Islamic Republic of Iran.
Abstract:   (4499 Views)
In critically ill infants and children, intravascular (IV) access is sometimes very difficult. In such cases intraosseous (IO) infusion should be used as the method of choice. However, in practice, different problems are experienced with this procedure. To overcome the practical problems and to confirm the efficacy of IO infusion in reversing hypovolemic shock, an animal model was used by employing three rabbits. In rabbit I, after insertion of a 14-gauge bone marrow aspiration needle in the proximal tibia, the flow rate of normal saline was very slow by gravity, but pressure infusion devices including manual pushing with a syringe, blood pressure cuffs, or infusion pumps all increased the flow rate remarkably. In rabbit II, the circulation time of a dye given by IO route was very short therefore drugs are expected to appear in the systemic circulation shortly after IO injection. In rabbit III, hypovolemic shock was induced by withdrawing blood and then, rapidly and successfully treated by IO infusion of normal saline.
Keywords: Intraosseous infusion, hypovolemic shock, animal model.
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Type of Study: Original Research: Basic Science in Medicine | Subject: Pediatric
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