Volume 10, Number 2 (8-1996)                   Med J Islam Repub Iran 1996 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

HAKOPIAN V P, KANAYAN A S, MELKONIAN K V. THE MORPHO-FUNCTIONAL STATE OF THE BRAIN UNDER CONDITIONS OF HYPOKINESIA AND ITS POSSIBLE PHARMACOLOGICAL CORRECTION BY GABA-ERGIC SUBSTANCES. Med J Islam Repub Iran. 1996; 10 (2) :153-158
URL: http://mjiri.iums.ac.ir/article-1-1204-en.html

From the Department of Pharmacology, State Medical Institute, Yerevan, Republic of Armenia.
Abstract:   (1506 Views)
In this paper it has been shown that deterioration of the brain cortex capillary system and negative dynamics of cerebral tissue morphology occur under conditions of hypo kinesia. Simultaneously, gamma-aminobutyric acid (GABA) and piracetam have been shown to favor the development of vasodilation and prevent further worsening of the cerebral blood supply. During the experiment, it was also established that among the substances investigated, the specific antagonist of GABA-receptors-bicuculline-displays the strongest cerebroprotective effect in early hypokinesia.
Full-Text [PDF 896 kb]   (753 Downloads)