Volume 9, Issue 3 (10-1995)                   Med J Islam Repub Iran 1995 | Back to browse issues page

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MOSHTAGHIE A, SANDUGHCHIN M, BADIL A, AZANI M. DEVELOPMENT OF A METHOD FOR ALUMINIUM DETERMINATION IN SERUM AND DIALYSIS FLUID BY FLAMELESS ATOMIC ABSORPTION WITH GRAPHITE FURNACE. Med J Islam Repub Iran. 1995; 9 (3) :233-237
URL: http://mjiri.iums.ac.ir/article-1-1324-en.html
From the Department of Biochemistry, School of Pharmacy Isfahan University of Medical Sciences, Isfahan
Abstract:   (2916 Views)
Aluminium determination was carried out in serum and dialysis fluid by a simple and reliable method of nameless atomic absorption with graphite furnace . . No preparatory procedures are required for water and dialysis fluid. In this method serum was mixed with 0.2% HNO, to allow complete combustion of the samples in order to improve analytical precision. The method has a sensitivity of 15 pg and detection limit of 2.1 µg AI/L. The aluminium contents of the main water supply, be-distilled water and dialysis fluid were 52, I, and 44 µg/L respectively. The mean value for normal serum aluminium in Isfahan was 3.6 µg/L. Serum aluminium concentration in chronic renal failure was measured in pre- and post-dialysis samples. The mean values for the serum aluminium levels pre- and post-dialysis were 30.5 and 71.08 µg/L with a range of 9-60 and 21-123 µg/L, respectively. Pre- and post-dialysis serum aluminium values in female patients were within the range of 1-42 and 12- 66 µg/L with mean values of 18.25 and 40.5 µg/L, respectively. Instrumental settings and sample handling are discussed.
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