Volume 22, Number 4 (2-2009)                   Med J Islam Repub Iran 2009 | Back to browse issues page


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Froutan Pishbijari, H, Assefi Rad, M, Baghi, I. Gastric Cancer in people below and above 40 is it different?. Med J Islam Repub Iran. 2009; 22 (4) :170-174
URL: http://mjiri.iums.ac.ir/article-1-14-en.html

Professor of Gastroenterology Department of Gastroenterology, Imam Khomeini Hospital, , Froutan@ams.ac.ir
Abstract:   (3208 Views)

  Abstract

  Background: Gastric cancer is the second most common cancer and also the second

  cancer related death all over the world. In recent years recorded data for tumor

  has shown a rise in the incidence of gastric cancer in young individuals. The present

  study was designed to compare some of the epidemiologic characteristics of individuals

  suffering from gastric cancer aged below and above forty years.

  Methods: This cross-sectional study was performed on 389 patients suffering

  from gastric cancer referred to a referral private clinic in Tehran during the years

  1991 and 2001. The patients were divided into two groups, those older than 40 years

  and the younger ones. The demographic information, the tumor type and location as

  well as the prevalence of the H. pylori infection was compared in the two groups. The

  collected data were entered in SPSS version 13 and analyzed using chi-square and

  fisher exact test.

  Results: Fifty patients (12.9%) were reported to be lower than 40 years. The mean

  age of the patients in this group was 32.1±6.8years while the number was calculated

  to be 63.23 ± 9.7 years in the other group. The male to female ratio in the group

  younger and older than 40 years was 1.9: 1 and 2.6:1, respectively. Adenocarcinama

  and lymphoma compromised 70% and 12% of the individuals younger than 40 years

  whereas they were reported in 89.3% and 3.2% of the patients in the other group.

  While cancer in the middle third of stomach was the most frequent type in both

  groups, the prevalence of upper third gastric cancer was considerably higher in those

  younger than 40 years old (19.9% vs. 5%). H. pylori infection was seen in 23.2% of

  the younger group, while more than 56% of the older group suffered from H. pylori

  infection. There was a statistically significant difference between the two groups

  (P<0.017).

  Conclusion: gastric cancer is not rare among the individuals younger than 40

  years old. The disease is reported to be seen in the absence of H. pylori infection in

  the majority of these cases. There is a considerable difference between the prevalence

  of malignant lymphoma in this group of patients compared with the older patients.

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Type of Study: Original Research | Subject: Endoscopy

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