Volume 7, Number 4 (2-1994)                   Med J Islam Repub Iran 1994 | Back to browse issues page


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FARHOUDl A, ESLAMI M, SHAKURNIA A. EVALUATION OF SERUM IgG SUBCLASS LEVELS IN ASTHMATIC AND ATOPIC CHILDREN WITH RECURRENT INFECTION. Med J Islam Repub Iran. 1994; 7 (4) :221-225
URL: http://mjiri.iums.ac.ir/article-1-1411-en.html

From the Department of Immunology and Allergy, Children's Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract:   (1491 Views)
Serum IgG subclass levels were measured using an indirect immunoenzymatic assay (ELISA) with monoclonal antibodies in 16 children with asthma and 13 children with atopy who had mostly recurrent infections. Seven of the asthmatic children had marked low or low normal levels of IgG4, six had marked low or low normal levels of IgG 3, two had marked low normal levels of both IgG2, and IgG 3 and one had low levels of IgG2 " IgG3, and IgG4 •. All these patients suffered from recurrent sinopulmonary infections. There were low percentages of IgG3, and IgG4. defects (about 15%) in the atopic patients, while a significant increase in the serum IgG4. levels were observed (six patient out of 13 patients, 46.2%).
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Type of Study: Original Research | Subject: Immunology