Volume 6, Issue 1 (5-1992)                   Med J Islam Repub Iran 1992 | Back to browse issues page

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From the Institute of Biochemistry and Biophysics, University of Tehran, Islamic Republic of Iran.
Abstract:   (3551 Views)
In this study the nature of chromosomal proteins, his tones and nonhistone in resident alveolar macrophages was investigated in comparison to peritoneal neutrophils and calf thymus proteins. Cells were obtained by lavaging the lung and after purity determination they were subjected to fractional extraction procedures. Proteins were then analysed on SDS polyacrylamide gels and densitometric scans were obtained. The results show that in macrophages, the pattern of histone and nonhistone proteins were similar to thymus proteins, two distinct and specific proteins HIĀ° and HMGI4b and also a protein with a molecular weight of I2kd (Hx) were present. These data suggest a different chromatin protein pattern in pulmonary alveolar macrophages.
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