Volume 4, Issue 1 (2-1990)                   Med J Islam Repub Iran 1990 | Back to browse issues page

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From the' Department of Histology, Tarbiat Modarres University
Abstract:   (3156 Views)
Twenty-two recipients of HLA-nonidentical living related and nonrelated renal allografts were studied for alterations in the relative percentage of OKT4-positive peripheral blood T-cells after transplantation. Characteristic shifts in the ratio of T-helper to T -suppressor/cytotoxic cells (TH/TS-C), but not absolute cell numbers, were demonstrated to correspond with the status of the allograft. Our results are indicative of a correlation between rejection episodes and the increase in OKT4:0KT8 ratios, that were characterized by a significant rise in the percentage of OKT4-positive cells (P=0.001), and a decrease in the percentage of OKT8-positive cells (P=0.001).
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