Volume 17, Issue 4 (2-2004)                   Med J Islam Repub Iran 2004 | Back to browse issues page

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AKHOONDIAN J, TALEBI S. HIGH-DOSE ORAL PYRIDOXINE FOR TREATMENT OF PEDIATRIC RECURRENT INTRACTABLE SEIZURES. Med J Islam Repub Iran 2004; 17 (4) :301-304
URL: http://mjiri.iums.ac.ir/article-1-1615-en.html
HIGH-DOSE ORAL PYRIDOXINE FOR TREATMENT OF PEDIATRIC RECURRENT INTRACTABLE SEIZURES
JAVAD AKHOONDIAN , SAEED TALEBI
From the Department of Pediatric Neurology, Ghaem General Hospital, Mashhad University of Medical , j-akhondian@mums.ac.ir
Abstract:   (4930 Views)
Intractable epilepsy is a common clinical problem in pediatrics and approximately 13% of children with epilepsy experience intractable seizures. To determine the efficacy of pyridoxine in treating seizures, 30 infants and children with recurrent seizures were enrolled in the present study. All of them were treated with high-dose oral pyridoxine (40 mg/kg/day), as an adjunct to antiepileptic drugs. Clinical efficacy criteria were based on the daily frequency of seizures after therapy was initiated during the following three weeks. The results indicated that the mean frequency of seizures decreased significantly from the first (16.2±11) to the fourth visit (7±6.2) (p
Keywords: Intractable seizure, Pyridoxine, Antiepileptic
Full-Text [PDF 233 kb]   (4231 Downloads)    
Type of Study: Original Research | Subject: Pediatric
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