Volume 17, Number 4 (2-2004)                   Med J Islam Repub Iran 2004 | Back to browse issues page


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AKHOONDIAN J, TALEBI S. HIGH-DOSE ORAL PYRIDOXINE FOR TREATMENT OF PEDIATRIC RECURRENT INTRACTABLE SEIZURES. Med J Islam Repub Iran. 2004; 17 (4) :301-304
URL: http://mjiri.iums.ac.ir/article-1-1615-en.html

From the Department of Pediatric Neurology, Ghaem General Hospital, Mashhad University of Medical , j-akhondian@mums.ac.ir
Abstract:   (1771 Views)
Intractable epilepsy is a common clinical problem in pediatrics and approximately 13% of children with epilepsy experience intractable seizures. To determine the efficacy of pyridoxine in treating seizures, 30 infants and children with recurrent seizures were enrolled in the present study. All of them were treated with high-dose oral pyridoxine (40 mg/kg/day), as an adjunct to antiepileptic drugs. Clinical efficacy criteria were based on the daily frequency of seizures after therapy was initiated during the following three weeks. The results indicated that the mean frequency of seizures decreased significantly from the first (16.2±11) to the fourth visit (7±6.2) (p
Full-Text [PDF 233 kb]   (960 Downloads)    
Type of Study: Original Research | Subject: Pediatric

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