Volume 31, Number 1 (1-2017)                   Med J Islam Repub Iran 2017 | Back to browse issues page




DOI: 10.18869/mjiri.31.19

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Khalessi N, Mazouri A, Bassirnia M, Afsharkhas L. Comparison between serum magnesium levels of asphyxiated neonates and normal cases . Med J Islam Repub Iran. 2017; 31 (1) :110-112
URL: http://mjiri.iums.ac.ir/article-1-3418-en.html

Ali-Asghar Children’s Hospital, Iran University of Medical Science, Tehran, Iran.
Abstract:   (396 Views)

Background: Asphyxia is one the most important causes of neonatal mortality and morbidity. It is suggested that magnesium may have a protective role against cellular damage during hypoxic brain insult, or change effect post-asphyxia consequences. Our study was performed for comparison of serum magnesium in neonates with and without asphyxia.

   Methods: This study was done in Neonatal Ward of Ali-Asghar hospital, from January 2010 to 2011 in Tehran, Iran. Serum magnesium levels of seventy-six cases with a diagnosis of asphyxia grade 2 were compared with 76 normal newborns. Collected data including gestational age, sex, birth weight and serum magnesium levels were analyzed by SPSS software.

  Results: Of 152 neonates, 81 (53.3%) were male. Mean gestational age was 37.9 ± 1.07 weeks. Mean birth weights were 3172.9± 411.20 grams. Mean serum magnesium levels were compared in asphyxiated and normal neonates and between two groups significant difference was found (p=0.01). The odds ratio was 2.188 (with lower1.826, upper 2.626 and confidence interval 95 percent) which suggested a significant correlation between asphyxia and hypomagnesemia. 

  Conclusion: This study showed that serum magnesium levels in neonates with asphyxia was significantly lower than normal neonates and asphyxia can lead to hypomagnesemia.

Keywords: Asphyxia, Magnesium, Neonate
Full-Text [PDF 377 kb]   (138 Downloads)    
Type of Study: Original Research | Subject: Neonatal