Volume 23, Issue 1 (5-2009)                   Med J Islam Repub Iran 2009 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghanei E, Homayouni S M, Nasrollahi A. Two cases of pseudoxanthoma elasticum with renal involvement. Med J Islam Repub Iran. 2009; 23 (1) :53-57
URL: http://mjiri.iums.ac.ir/article-1-46-en.html

Assistant professor Department of Internal Medicine of Shohada Hospital Shahid Beheshti University of Medical Sciences , dr-e-ghanei@yahoo.com
Abstract:   (3320 Views)

  Abstract

  Pseudoxanthoma elasticum is a rare, hereditary, multisystemic disease affecting

  the skin, eye, and cardiovascular system. Renal involvement is uncommon.

  We describe two cases of pseudoxanthoma elasticum (PXE) in two women with

  distinctive skin lesions and nephrocalcinosis that renal ultrasonography showed a

  characteristic pattern of dotted increased echogenicity in the corticomedullary junction.

  One of them had IgA nephropathy that was proven by kidney biopsy. Skin biopsy

  and fundus examination confirmed the diagnosis. Early diagnosis of PXE is important

  for minimizing systematic complications and informing the other family

  members through genetic counseling. Our case with PXE and IgA nephropathy is the

  first case report.

Full-Text [PDF 138 kb]   (899 Downloads)    
Type of Study: case report | Subject: Internal Medicine

Send email to the article author