Volume 26, Number 2 (5-2012)                   Med J Islam Repub Iran 2012 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mehrpour M, Khuzan M, Najimi N, Motamed M R, Fereshtehnejad S. Serum uric acid level in acute stroke patients. Med J Islam Repub Iran. 2012; 26 (2) :66-72
URL: http://mjiri.iums.ac.ir/article-1-499-en.html

MD., MPH Assistant professor Stroke center, Firoozgar General Hospital, Tehran universityof Medical Sciences. , m-mehrpour@tums.ac.ir
Abstract:   (3497 Views)

 Background: The role of uric acid as a risk factor for vascular disease and acute stroke is controversial and there is little information about it. In this study, we determined serum uric acid levels in patients with acute stroke and assessed its relationship with cerebrovascular risk factors.

 Methods: In this cross sectional study, we assessed patients with acute stroke who were admitted in Firoozgar Hospital from September 2010 to March 2011. Clinical records of patients and their serum uric acid level was investigated. Finally, collected data were analyzed using SPSS software Ver.16.

 Results: Fifty five patients with acute stroke were evaluated who 25 of these patients (45.5%) were female and 30 of them (54.5%) were male. The mean age of patients was 67±14 years. Mean serum uric acid levels in the patients studied 5.94±1.70 mg/dl, and about half of the patients (47.3%) were hyperuricemic. There was a significant negative correlation between age of patients and their serum uric acid level (p=0.04, R =-0.27). Uric acid level was significantly higher in men than women (p=0.03). Hyperuricemia was associated with increased amounts of triglycerides and Low-density lipoprotein (LDL) cholesterol (p=0.03, p=0.02). In patients with acute stroke, there was no significant association between serum uric acid level and diabetes mellitus, hypertension, history of ischemic heart disease, smoking, prescription rTPA, and type of stroke.

 Conclusion: Due to the high prevalence of hyperuricemia in patients with acute stroke, and its accompanying increase in triglyceride and LDL cholesterol levels, it can be considered as a risk factor for acute stroke.

Full-Text [PDF 188 kb]   (1233 Downloads)    
Type of Study: Original Research | Subject: Neurology

Send email to the article author