Volume 14, Number 3 (11-2000)                   Med J Islam Repub Iran 2000 | Back to browse issues page


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GHADERI A, SHOSHTARI J, FARJADIAN S, YOUSEFI-POUR G, AMIRZARGAR A. HLA-DRBI ALLELE FREQUENCY IN MYAS THENIA GRAVIS PATIENTS FROM SOUTHERN IRAN. Med J Islam Repub Iran. 2000; 14 (3) :223-225
URL: http://mjiri.iums.ac.ir/article-1-857-en.html

From the Departments of Immunology and Neurology, Unit of Internal Medicine, Medical School, Shiraz University of Medical Sciences, Shiraz, I.R. Iran , immunol@sums.ac.ir
Abstract:   (1695 Views)
HLA-DRB1 allele frequencies of 28 myasthenia gravis (MG) patients, residents of southern Iranian provinces, were studied using PCR-SSP method. The control group consisted of 100 healthy individuals of the same ethnic group. The allele HLA-DRB1 * 16 (RR= 2.04, p= 0.028) was found to be significantly increased in MG patients compared to the control group, whereas HLADRB1 * 15(RR= 0.17 p= 0.043) and HLA-DRB1 *07 (p= 0.036) were found to be significantly increased in the control group compared to the patients, and seem to be negatively associated with the disease.
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Type of Study: Original Research | Subject: Immunology

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