TY - JOUR JF - MJIRI JO - Med J Islam Repub Iran VL - 11 IS - 3 PY - 1997 Y1 - 1997/11/01 TI - EFFECT OF FIVE ALPHA DIHYDROTESTOSTERONE (5α-DHT) ON CYTOKINE PRODUCTION BY PERITONEAL MACROPHAGES OF NZB/BALBc MICE TT - N2 - One of the mechanisms involved in the regulation of the immune system by steroid hormones could be the monocytic-macrophage system. In this study the effect of the male hormone 5a-DHT on cytokine release by peritoneal macrophages (mΦ) of male and female NZB/BALBc mice was investigated. Macrophages from male mice activated with LPS produced a greater amount of IL-1β (21.8%) (p SP - 223 EP - 228 AU - AHMADI-RENANI, KAZEM AU - McCRUDEN, ALAN B. AD - From the Department of Immunology, Faculty of Medicine Baghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran KW - Macrophage KW - Sex hormone KW - 5α-DHT KW - Cytokine. UR - http://mjiri.iums.ac.ir/article-1-1095-en.html ER -