AU - Aminimoghaddam, Soheila AU - Yarandi, Fariba AU - Nejadsalami, Forough AU - Taftachi, Farrokh AU - Noorbakhsh, Fereshteh AU - Mahmoudzadeh, Fatemeh TI - Human chorionic gonadotrophin as an indicator of persistent ges-tational trophoblastic neoplasia PT - JOURNAL ARTICLE TA - MJIRI JN - MJIRI VO - 28 VI - 1 IP - 1 4099 - http://mjiri.iums.ac.ir/article-1-2317-en.html 4100 - http://mjiri.iums.ac.ir/article-1-2317-en.pdf SO - MJIRI 1 AB  -   Background : Gestational trophoblastic neoplasia (GTN) disease is excessive and inappropriate proliferation of trophoblast after termination of the pregnancy. Many attempts have been made to improve follow-up procedures, but no studies have evaluated Human Chorionic Gonadotrophin (HCG) as a post treatment indicator. Thus we aimed to know β-HCG variability in post treatment pregnancies.   Methods: 40 Molar affected pregnancies were followed post-surgical treatment by serum β-HCG level in a tertiary level hospital. All subjects were treated by evacuation and followed by β-HCG every week for three weeks, then every month for six months.   Results: 30 women were normal (group I) and 10 (group II) diagnosed as GTN cases. Serum β-HCG which obtained serially shown significant differences between two groups (p=0.001). The quantity of β-HCG/week had significantly higher level than normal females ( p CP - IRAN IN - Tehran University of Medical Sciences, Tehran, Iran. LG - eng PB - MJIRI PG - 272 PT - Original Research YR - 2014