TY - JOUR T1 - IMPACT OF IODIZED OIL INJECTION DURING PREGNANCY ON THYROID FUNCTION TESTS OF OFFSPRINGS TT - JF - MJIRI JO - MJIRI VL - 17 IS - 4 UR - http://mjiri.iums.ac.ir/article-1-665-en.html Y1 - 2004 SP - 277 EP - 283 KW - Iodized oil KW - Pregnancy KW - Neonates KW - Thyroid function N2 - Previous studies have shown that injection of iodized oil in pregnant women can be used as a prophylactic strategy for iodine deficiency disorders and may improve the growth indices of their offspring. Since administration of pharmacological doses of iodine may lead occasionally to large goiter and rarely to hypothyroidism, in the present study the thyroid function tests of neonates and infants born to women who had received 480 mg iodized oil intramuscularly during pregnancy were assessed and compared to those of a control group. Of 277 cord blood samples obtained from Mazandaran and Khohkiluyeh-Boyerahmad provinces, 125 made up the case (injected) and 152 the control (noninjected) group. Of 1026 blood samples of the neonates and infants from Mazandaran province, 544 made up the case and 482 the control group. Serum T4, T3 and TSH concentrations were measured with RIA kits. In the cord blood samples, mean serum T4 in cases who had received iodized oil was lower than that of the control group: 140±32 vs. 149±33 nmol/L, respectively p M3 ER -