TY - JOUR JF - MJIRI JO - Med J Islam Repub Iran VL - 14 IS - 3 PY - 2000 Y1 - 2000/11/01 TI - HLA-DRBI ALLELE FREQUENCY IN MYAS THENIA GRAVIS PATIENTS FROM SOUTHERN IRAN TT - N2 - HLA-DRB1 allele frequencies of 28 myasthenia gravis (MG) patients, residents of southern Iranian provinces, were studied using PCR-SSP method. The control group consisted of 100 healthy individuals of the same ethnic group. The allele HLA-DRB1 * 16 (RR= 2.04, p= 0.028) was found to be significantly increased in MG patients compared to the control group, whereas HLADRB1 * 15(RR= 0.17 p= 0.043) and HLA-DRB1 *07 (p= 0.036) were found to be significantly increased in the control group compared to the patients, and seem to be negatively associated with the disease. SP - 223 EP - 225 AU - GHADERI, A AU - SHOSHTARI, J AU - FARJADIAN, S AU - YOUSEFI-POUR, GH AU - AMIRZARGAR, A AD - From the Departments of Immunology and Neurology, Unit of Internal Medicine, Medical School, Shiraz University of Medical Sciences, Shiraz, I.R. Iran KW - Myasthenia gravis KW - HLA-DRBl KW - PCR-SSP UR - http://mjiri.iums.ac.ir/article-1-857-en.html ER -