TY - JOUR T1 - TREATMENT OF HELICOBACTER PYLORI (H. PYLORI) INFECTION IN CHILDREN: A PROSPECTIVE STUDY COMPA R ING TWO DIFFERENT THERAPEUTIC REGIMENS TT - JF - MJIRI JO - MJIRI VL - 12 IS - 2 UR - http://mjiri.iums.ac.ir/article-1-1016-en.html Y1 - 1998 SP - 119 EP - 121 KW - Chronic abdominal pain KW - children KW - endoscopy KW - urease test KW - H. pylori KW - antibiotic therapy. N2 - During a period of 10 months from May to February 1995, 120 children (72 girls, 48 boys) with an age range of 4-16 years (mean age 10.87, S.D.±2.7) with chronic abdominal pain who had an abnormal endoscopy (gastroduodenal mucosal defect) and positive urease test were treated for H. pylori. Patients were treated randomly with either metronidazole and amoxicillin (double therapy, group A) or metronidazole, amoxicillin and bismuth subsalicylate (triple therapy, group B), each for two weeks. 6-8 weeks after completion of treatment, patients were reevaluated by endoscopy and urease test. Endoscopy was normal in 75 cases (63 % ). Of the 45 cases with abnormal endoscopy, 37 patients (82%) were in group A and 8 patients (18%) in group B (p M3 ER -