%0 Journal Article %A BABADIZAVANDY, ESMAT %A SEYYEDI ALAVI, GHODSIH %A CORDI, MASOMEH %T THE EFFECT OF C ALCIUM SUPPLEMENTATION IN THE PREVENTION OF HYPERTENSIVE DISORDERS OF PREGN ANCY IN NULLIPAROUS WOMEN %J Medical Journal of the Islamic Republic Of Iran %V 12 %N 1 %U http://mjiri.iums.ac.ir/article-1-1039-en.html %R %D 1998 %K %X The purpose of this prospective study was to determine the effect of calcium supplementation in the incidence of hypertensive disorders of pregnancy (gestational hypertension and pre-eclampsia) in nulliparous and high risk women. 300 pregnant women in the 24th week of gestation at the beginning of the study were entered into a double-blind randomized trial. 143 of them who had a positive roll-over test and hypocalciuria at the 28-32nd week of gestation were enrolled for the study. Subjects were assigned to receive 2 g per day of elemental calcium (52 women) or placebo (61 women) from the 28-32nd week of pregnancy until delivery. Results showed that 11.4% of calcium-treated subjects developed gestational hypertension, compared to 31.2% of the placebo group. The rate of hypertensive disorders of pregnancy was also higher in the placebo group (35.6% vs 11.4%, p %> http://mjiri.iums.ac.ir/article-1-1039-en.pdf %P 11-14 %& 11 %! Prevention of PIH with Calcium Supplementation %9 Original Research %L A-10-298-489 %+ From the Department of Nursery and Midwifery, Mashhad University, Mashhad, Islamic Republic of Iran. %G eng %@ 1016-1430 %[ 1998