AU - BABADIZAVANDY, ESMAT AU - SEYYEDI ALAVI, GHODSIH AU - CORDI, MASOMEH TI - THE EFFECT OF C ALCIUM SUPPLEMENTATION IN THE PREVENTION OF HYPERTENSIVE DISORDERS OF PREGN ANCY IN NULLIPAROUS WOMEN PT - JOURNAL ARTICLE TA - MJIRI JN - MJIRI VO - 12 VI - 1 IP - 1 4099 - http://mjiri.iums.ac.ir/article-1-1039-en.html 4100 - http://mjiri.iums.ac.ir/article-1-1039-en.pdf SO - MJIRI 1 ABĀ  - The purpose of this prospective study was to determine the effect of calcium supplementation in the incidence of hypertensive disorders of pregnancy (gestational hypertension and pre-eclampsia) in nulliparous and high risk women. 300 pregnant women in the 24th week of gestation at the beginning of the study were entered into a double-blind randomized trial. 143 of them who had a positive roll-over test and hypocalciuria at the 28-32nd week of gestation were enrolled for the study. Subjects were assigned to receive 2 g per day of elemental calcium (52 women) or placebo (61 women) from the 28-32nd week of pregnancy until delivery. Results showed that 11.4% of calcium-treated subjects developed gestational hypertension, compared to 31.2% of the placebo group. The rate of hypertensive disorders of pregnancy was also higher in the placebo group (35.6% vs 11.4%, p CP - IRAN IN - LG - eng PB - MJIRI PG - 11 PT - Original Research YR - 1998