TY - JOUR JF - MJIRI JO - Med J Islam Repub Iran VL - 12 IS - 1 PY - 1998 Y1 - 1998/5/01 TI - THE EFFECT OF C ALCIUM SUPPLEMENTATION IN THE PREVENTION OF HYPERTENSIVE DISORDERS OF PREGN ANCY IN NULLIPAROUS WOMEN TT - N2 - The purpose of this prospective study was to determine the effect of calcium supplementation in the incidence of hypertensive disorders of pregnancy (gestational hypertension and pre-eclampsia) in nulliparous and high risk women. 300 pregnant women in the 24th week of gestation at the beginning of the study were entered into a double-blind randomized trial. 143 of them who had a positive roll-over test and hypocalciuria at the 28-32nd week of gestation were enrolled for the study. Subjects were assigned to receive 2 g per day of elemental calcium (52 women) or placebo (61 women) from the 28-32nd week of pregnancy until delivery. Results showed that 11.4% of calcium-treated subjects developed gestational hypertension, compared to 31.2% of the placebo group. The rate of hypertensive disorders of pregnancy was also higher in the placebo group (35.6% vs 11.4%, p SP - 11 EP - 14 AU - BABADIZAVANDY, ESMAT AU - SEYYEDI ALAVI, GHODSIH AU - CORDI, MASOMEH AD - From the Department of Nursery and Midwifery, Mashhad University, Mashhad, Islamic Republic of Iran. UR - http://mjiri.iums.ac.ir/article-1-1039-en.html ER -