AU - MAKVANDI, ME AU - DIGHE, PY AU - KALANTARI, H TI - STUDIES ON HEPATITIS B VACCINES PT - JOURNAL ARTICLE TA - MJIRI JN - MJIRI VO - 4 VI - 2 IP - 2 4099 - http://mjiri.iums.ac.ir/article-1-1559-en.html 4100 - http://mjiri.iums.ac.ir/article-1-1559-en.pdf SO - MJIRI 2 ABĀ  - HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Green Cross Corporation, Osaka, Japan). We conclude that vaccine prepared by PEG-6000 precipitation gives better results. CP - IRAN IN - LG - eng PB - MJIRI PG - 125 PT - Original Research: Basic Science in Medicine YR - 1990