%0 Journal Article %A Nikbakhsh, Novin %A Moudi, Sussan %A Alvarzandi, Sara %A Niazifar, Maede %A Farnoush, Nazila %A Bijani, Ali %A Moudi, Marjan %T Citalopram and group psychotherapy in breast cancer patients: A randomized clinical trial %J Medical Journal of the Islamic Republic Of Iran %V 32 %N 1 %U http://mjiri.iums.ac.ir/article-1-4426-en.html %R 10.14196/mjiri.32.68 %D 2018 %K Breast cancer, Depression, Anxiety, Citalopram, Group psychotherapy, %X Background: Depression is a common psychiatric disorder in breast cancer patients. This study was designed to evaluate the clinical efficacy of group psychotherapy on breast cancer patients with depressive disorder who took citalopram. Methods: This clinical trial was conducted on 40 breast cancer patients with depressive disorder. The control group received citalopram 20-40 mg/ day for 12 weeks and the intervention group participated in 8 sessions of group psychotherapy in addition to the same dose of citalopram. At the baseline and 3, 6, and 12 weeks after treatment, patients were followed- up. Treatment outcomes and quality of life were compared between the 2 groups. Results: Overall, the depression score of Hospital Anxiety and Depression Scale (HADS) at baseline with the mean of 11.6±1.6 was signed in the range of clinical depression and after intervention it declined to 8.8±3.6 (in the 3rd week), 7.1±3.9 (6th week), and 5.9±4.5 (12th week). Furthermore, HADS anxiety score at baseline with the mean of 12.6±2.6 was signed in the range of clinical anxiety and after intervention it declined to 9.1±3.0, 7.3±4.1, and 6.0±4.0, respectively. This improvement was significantly more in the combined therapy intervention group (p<0.001). The mean score of quality of life based on WHO QOL-BREF questionnaire increased by 1.85 fold in the case group, improved from 44.09 to 81.70, while the slight change was observed in the control group (p<0.001). During the treatment, no significant adverse drug event was observed in the 2 groups (p>0.05). Conclusion: Group psychotherapy has a significant effect on improving depression, anxiety, and quality of life in breast cancer patients. %> http://mjiri.iums.ac.ir/article-1-4426-en.pdf %P 394-399 %& 394 %! %9 Original Research %L A-10-3401-1 %+ Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. %G eng %@ 1016-1430 %[ 2018