Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1391
5
1
gregorian
2012
8
1
26
3
online
1
fulltext
en
Effect of three different sanitizing solutions on the contaminated bone: an experimental study in the rabbit
Orthopedic Surgery
Orthopedic Surgery
Original Research
Original Research
<font size="3" face="Times New Roman"> </font><font face="Calibri"><font size="3"><b>Background:</b> To determine the efficacy of three different antiseptic solutions (Control group (I), Antibiotic solution – Neomycin and polymyxin (II), Chlorhexidine 0.4% (III), and povidone – iodine 10% (IV)) in disinfecting contaminated bone fragments.<p></p></font></font><font size="3" face="Times New Roman"> </font><p style="TEXT-ALIGN: justify MARGIN: 0in 0in 10pt" class="MsoNormal"><font face="Calibri"><font size="3"><b>Methods:</b> Under sterile conditions, the femora of 12 rabbits were removed and cut into six millimeter pieces. A total of 200 bone specimens were obtained. All 200 specimens were dropped on the operating room floor for fifteen seconds and assigned to one of four experimental groups. Group I samples were cultured after immersion in normal saline solution (Control group). In other three groups, prior to culture the samples, they were washed with normal saline for ninety seconds and placed in an antibiotic solution (Neomycin & Polymyxin) (group II), Chlorhexidine 0.4% (group III), and povidone-iodine 10% (group IV) respectively.<p></p></font></font></p><font size="3" face="Times New Roman"> </font><font face="Calibri"><font size="3"><b>Results:</b> In group I, 22 of 50 specimens had positive cultures. Of 50 specimens of group II and IV, positive cultures were found in 3 and 2 grafts respectively after 10 days whereas no positive cultures were detected in any samples of group III.<p></p></font></font><font size="3" face="Times New Roman"> </font><p style="TEXT-ALIGN: justify MARGIN: 0in 0in 10pt" class="MsoNormal"><font size="3"><font face="Calibri"><b>Conclusion:</b> Chlorhexidine 0.4% seems to be the best antiseptic solution for discontaminating the contaminated bone samples although it did not have any significant difference with povidone-iodine and other antibiotic solution.<p></p></font></font></p><font size="3" face="Times New Roman"> </font>
Sanitizing solutions, Contaminated bone.
114
117
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-315&slc_lang=en&sid=1
Hamidreza
Yazdi
dr.yazdi88@yahoo.com
20031947532846007450
20031947532846007450
No
Tehran University of Medical Sciences, Tehran, Iran.
Mehdi
Ramezan Shirazi
mehdi.shirazi@yahoo.co.uk.
20031947532846007451
20031947532846007451
Yes
15th Khordad Hospital, Gonabad University of Medical Sciences, Gonabad, Khorasan, Iran.
Omid
Momen Shouli
momenshouli@yahoo.com
20031947532846007452
20031947532846007452
No
Gilan University of Medical Sciences, Gilan, Iran.
Farzad
Yazdi
farzad.yazdi@yahoo.com
20031947532846007453
20031947532846007453
No
Shahrekord Azad University, Iran.
Alireza
Moslem
alirezamoslem@gmail.com
20031947532846007454
20031947532846007454
No
Gonabad University of Medical Sciences, Khorasan, Iran.