Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1376
5
1
gregorian
1997
8
1
11
2
online
1
fulltext
en
VENTROMEDIAL HYPOTHALAMIC NUCLEI AND FEEDING BEHAVIOR
Physiology
Physiology
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
The role of the ventromedial nuclei of the hypothalamus (VMN) in food
behavior was studied in adult male rats, allocated in 3 groups: control, sham and
lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec).
Results revealed a significant decrease (p<O.05) in body weight (BW) and food
intake (FI) in the order of lesioned <sham <control during the fIrst week. However,
there were no significant differences in BW and FI between groups in the second
week after lesion induction. In the lesioned group, the fInikiness syndrome was
observed in the second week after lesioning. It was postulated that VMN lesions
produce the finikiness syndrome, and this in turn can cause hyperphagia and
hypothalamic obesity. Water intake (WI) was significantly lower in the lesioned
group in the first and second week after VMN lesion induction. It could be
postulated that disturbances in the regulation of WI is part of the VMN lesion
syndrome.
VMN lesion, food intake, water intake, finikiness.
127
131
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-376&slc_lang=en&sid=1
GD
NAYERI KAMAN
20031947532846005178
20031947532846005178
Yes
From the Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, and the *Department of Physiology, Tarbiat Modarress University, Tehran, Islamic Republic of Iran.
M
TAHERIAN FARD
20031947532846005179
20031947532846005179
No