Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1375
8
1
gregorian
1996
11
1
10
3
online
1
fulltext
en
PRACTICAL PROBLEMS AND THE EFFICACY OF INTRAOSSEOUS INFUSION: SOLVING THE PROBLEMS BY EMPLOYING AN ANIMAL MODEL
Pediatric
Pediatric
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
In critically ill infants and children, intravascular (IV) access is sometimes
very difficult. In such cases intraosseous (IO) infusion should be used as the
method of choice. However, in practice, different problems are experienced with
this procedure. To overcome the practical problems and to confirm the efficacy of
IO infusion in reversing hypovolemic shock, an animal model was used by
employing three rabbits. In rabbit I, after insertion of a 14-gauge bone marrow
aspiration needle in the proximal tibia, the flow rate of normal saline was very slow
by gravity, but pressure infusion devices including manual pushing with a syringe,
blood pressure cuffs, or infusion pumps all increased the flow rate remarkably. In
rabbit II, the circulation time of a dye given by IO route was very short therefore
drugs are expected to appear in the systemic circulation shortly after IO injection.
In rabbit III, hypovolemic shock was induced by withdrawing blood and then,
rapidly and successfully treated by IO infusion of normal saline.
Intraosseous infusion, hypovolemic shock, animal model.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-433&slc_lang=en&sid=1
PEDRAM
NIKNAFS
20031947532846005358
20031947532846005358
Yes
From the Departments of Pediatrics Kerman University of Medical Sciences and Health Services, Kerman, Islamic Republic of Iran.
ALlREZA
SOTUDEHNEJAD
20031947532846005359
20031947532846005359
No
From the Departments of Surgery Kerman University of Medical Sciences and Health Services, Kerman, Islamic Republic of Iran.
HAMID
TABRIZCHI
20031947532846005360
20031947532846005360
No
From the Departments of Pathology, Kerman University of Medical Sciences and Health Services, Kerman, Islamic Republic of Iran.