Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1375
5
1
gregorian
1996
8
1
10
2
online
1
fulltext
en
THE MORPHO-FUNCTIONAL STATE OF THE BRAIN UNDER CONDITIONS OF HYPOKINESIA AND ITS POSSIBLE PHARMACOLOGICAL CORRECTION BY GABA-ERGIC SUBSTANCES
Pharmacology
Pharmacology
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
In this paper it has been shown that deterioration of the brain cortex capillary
system and negative dynamics of cerebral tissue morphology occur under conditions
of hypo kinesia. Simultaneously, gamma-aminobutyric acid (GABA) and piracetam
have been shown to favor the development of vasodilation and prevent further
worsening of the cerebral blood supply. During the experiment, it was also
established that among the substances investigated, the specific antagonist of
GABA-receptors-bicuculline-displays the strongest cerebroprotective effect in
early hypokinesia.
153
158
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-448&slc_lang=en&sid=1
VILEN P.
HAKOPIAN
20031947532846005403
20031947532846005403
Yes
From the Department of Pharmacology, State Medical Institute, Yerevan, Republic of Armenia.
ALEXANDER S.
KANAYAN
20031947532846005404
20031947532846005404
No
KARINE V.
MELKONIAN
20031947532846005405
20031947532846005405
No