Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1375
2
1
gregorian
1996
5
1
10
1
online
1
fulltext
en
PREPARATION AN D CLINICAL EVALUATION OF SOME ANTI-ANORECTAL DISEASE DRUGS OBTAINED FROM MEDICINAL PLANTS
Pharmacology
Pharmacology
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
The hydroalcoholic extracts of dried ligulate florets of Calendula officinalis
L., dried leaves of Plantago major L., and dried aerial parts of Vinca major L. were
prepared and used as the main active ingredients of two types of anti-anorectal
disease ointments and suppositories. Benzocaine was used in one of the
formulations, while a mixture of belladonna dry extract and ephedrine sulfate was
used in the other. The effects of both prepared formulations were investigated in
patients suffering from anorectal diseases, using relevant placebos for
comparison.
The results indicated that the prepared drugs were significantly effective in the
treatment of anorectal diseases. Formulations containing benzocaine proved to be
more effective in patients suffering from hemorrhoids, while formulations containing
belladonna dry extract and ephedrine sulfate were more effective in anal
fissure and proctitis.
Anti-Anorectal Disease Plants; Calendula officinalis; Plantago major; Vinca major.
73
77
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-468&slc_lang=en&sid=1
SULEIMAN
AFSHARYPOUR
20031947532846005474
20031947532846005474
Yes
From the Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan
KlANDOKHT
SHAFII
20031947532846005475
20031947532846005475
No
From the Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan
MOHAMMAD ESMAIL
AKBARY
20031947532846005476
20031947532846005476
No
the School of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran
MOHAMMAD REZA
ZARGARZADEH
20031947532846005477
20031947532846005477
No
From the Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan