Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1374
5
1
gregorian
1995
8
1
9
2
online
1
fulltext
en
EVALUATION OF DIRECT MICROSCOPY, CULTURE, AND POLYMERASE CHAIN REACTION FOR THE DIAGNOSIS OF TUBERCULOUS MENINGITIS
Microbiology and Anatomy
Microbiology and Anatomy
Original Research
Original Research
In view of the importance of early diagnosis of tuberculous meningitis
(TBM), the efficiency of the polymerase chain reaction (PCR), one of the most
reliable and sensitive DNA-based assays, was compared with conventional
methods (acid-fast microscopy and culture) for the detection of M. tuberculosis in
cerebrospinal fluid (CSF) specimens from patients suspected of TBM.
Of the 29 CSF specimens from highly probable TBM patients (based on
clinical features), 25 were positive by PCR (86.2%), was acid-fast microscopy (AFM) positive (3.4%), positive (17.2%).
No positive results were found by AFM, culture or PCR in the nontuberculous
control group. The results of this study indicate that application of
PCR should be extremely useful for the diagnosis of TBM.
107
110
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-537&slc_lang=en&sid=1
ABDOLNASSER
RAFI
20031947532846005908
20031947532846005908
Yes
From the Department of Medical Microbiology, University College London Medical School, University of London, London, England.
BABAK
BABAN
20031947532846005909
20031947532846005909
No