Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1368
8
1
gregorian
1989
11
1
3
3
online
1
fulltext
en
SERUM CONCENTRATIONS OF VARIOUS HORMONES FOLLOWING EXPOSURE TO CHEMICAL WEAPONS CONTAINING SULFUR MUSTARD
Endocrinology
Endocrinology
Original Research
Original Research
Serum concentration of FSH, LH, testosterone, prolactin, ACTH,
cortisol, TSH, T4, T3 and resin T3 uptake were measured in 146 men who
were exposed to vesicants used by the Iraqi regime a few days t04 weeks prior
to testing. Clinical and laboratory findings had confirmed the use of mustard
gas.
Mean serum concentrations of FSH, LH, TSH and prolactin were not
significantly different from normal values. Free T4 index (FT41) was
subnormal in 6 men, and its mean was somewhat decreased (7.4 ± 0.8 vs
normal 8.7 ± 1.2 P < 0.05). Free T3 index (FT31) was subnormal in 14 men,
and its mean was significantly lower than normal (92 ± 20 vs 130 ± 11 P <
0.001).
Serum testosterone concentration was subnormal in 42 men, and its
mean was significantly lower than normal (361 ± 254 vs 676 ± 273 ngldl P <
0.001). Serum cortisol was subnormal in 11 and above normal in 8 men, its
mean was not significantly different from normal values. There was an
increase in serum ACTH concentration.
We conclude that exposure to chemical weapons containing mustards
may cause severe alterations in serum concentrations of various hormones.
105
107
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-775&slc_lang=en&sid=1
F
AZIZI
20031947532846006532
20031947532846006532
Yes
From the Endocrine Research Center and the Department of Medicine, Shahid Beheshti University Of Medical Sciences, Tehran, Islamic Republic of Iran.
H
ELYASI
20031947532846006533
20031947532846006533
No
H
SOHRABPOUR
20031947532846006534
20031947532846006534
No
N
JALALI
20031947532846006535
20031947532846006535
No
M
NAFARABADI
20031947532846006536
20031947532846006536
No