Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1392
5
1
gregorian
2013
8
1
27
3
online
1
fulltext
en
Comparison of pre-operative bilirubin level in simple appendicitis and perforated appendicitis
Surgery
Surgery
Original Research
Original Research
<p> <strong> Background: </strong>Delay in diagnosis and treatment of perforated appendicitis may cause life-threatening complications. The aim of this study was to determine and compare pre-operative total and direct bilirubin levels in cases of simple and perforated acute appendicitis in order to improve the clinical decision making. </p><p> <strong> Methods: </strong>This prospective observational study included eighty patients who underwent open appendectomy, during a one-year period from March 2010 to March 2011 in the surgical department of Hazrat-e-Rasool Akram Hospital, an academic teaching hospital in Tehran- Iran. Pre-operative total and direct levels of bilirubin were compared in two groups of histologically proved appendicitis (simple and perforated), each including 40 patients. </p><p> <strong> Results: </strong>Eighty patients who underwent open appendectomy including 70% men and 30% women with a mean age of 34±11 years in Group I (perforated appendicitis) and 47.5% women and 52.5% men with a mean age of 33±14 in Group II (simple appendicitis) were included in this study. The mean bilirubin levels were higher for patients with perforated acute appendicitis compared to those with a non-perforated simple appendicitis (1.04±05 mg/dl vs 0.7±0.1 mg/dl) and this difference is highly significant (p<0.01). </p><p> <strong> Conclusion: </strong>Assessment of preoperative total bilirubin is useful for the differential diagnosis of perforated versus acute simple appendicitis and total bilirubin should be used as an independent parameter in the early diagnosis of appendix perforation. </p>
Appendicitis, Bilirubin, Hyperbilirubinemia, Perforated appendicitis.
109
112
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-581&slc_lang=en&sid=1
Mohammad
Vaziri
dr_m_vaziri@yahoo.com
20031947532846008494
20031947532846008494
No
Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Abdolreza
Pazouki
apazouki@yahoo.com
20031947532846008495
20031947532846008495
No
Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Zeinab
Tamannaie
zeinab_tamannaie@yahoo.com
20031947532846008496
20031947532846008496
Yes
Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farshid
Maghsoudloo
maghsoudlou.f@yahoo.com
20031947532846008497
20031947532846008497
No
Mohadeseh
Pishgahroudsari
mo.pishgah@yahoo.com
20031947532846008498
20031947532846008498
No
Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Shahla
Chaichian
shahlachaichian@yahoo.com
20031947532846008499
20031947532846008499
No
Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran. & Islamic Azad University, Tehran Medical Branch, Tehran, Iran.