Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1390
2
1
gregorian
2011
5
1
25
1
online
1
fulltext
en
Lead toxicity: a probable cause of abdominal pain in drug abusers
Internal Medicine & Gastroenterology
Internal Medicine & Gastroenterology
Original Research
Original Research
<p> <strong> Abstract </strong></p><p> <strong> Background: </strong>Lead toxicity is caused by ingestion, inhalation, or contact with particles or vapors containing lead. It can present with nonspecific signs and symptoms such as abdominal pain, constipation, irritability, difficulty concentrating, and anemia. In this study, we have tried to find a relationship between lead poisoning and drug abuse. </p><p> <strong> Methods: </strong>In a cross sectional study, drug addicts presenting with abdominal pain referring to GI center of </p><p> Imam Khomeini hospital in 2008 were observed. Patients having occupational contact with lead were excluded from the study. Required data included age, sex, clinical findings, Para clinic results and blood lead level. Results were analyzed through SPSS-15 software. </p><p> <strong> Results: </strong>42 patients (all male) with average age of 46.9 ± 10.1 years were included in the study. Average </p><p> blood lead level was 51.17±27.96µg/dl. 22 patients (52.6%) had lead toxicity. A significant relation was found between lead toxicity and mode of opium drug use however relation between lead toxicity and duration of addiction was not significant. Similarly, a meaningful relation was found between lead toxicity and abnormal liver function test, urine tests, ECG, presence of basophilic stippling and hyperuricemia. </p><p> <strong> Conclusion: </strong>There seems to be a significant relation between opium drug abuse and lead toxicity. Further </p><p> studies with more cases and ethnicities are needed. </p><p> </p>
Lead toxicity, opium, drug abusers, abdominal pain
16
20
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-139&slc_lang=en&sid=1
Hossein
Froutan
froutan@ams.ac.ir
20031947532846001527
20031947532846001527
Yes
Department of Gastroenterology, Imam Khomeini Hospital, Tehran University of Medical Sciences. Tehran; Iran
Alireza
Kashefi Zadeh
20031947532846001528
20031947532846001528
No
Department of Gastroenterology, Imam Khomeini Hospital, Keshavarz Blv. Tehran, Iran
Mohammad
Kalani
20031947532846001529
20031947532846001529
No
Department of Gastroenterology, Imam Khomeini Hospital, Keshavarz Blv. Tehran, Iran
Yasir
Andrabi
20031947532846001530
20031947532846001530
No
Department of Gastroenterology, Imam Khomeini Hospital, Keshavarz Blv, Tehran, Iran