Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1396
11
1
gregorian
2018
2
1
32
1
online
1
fulltext
en
Citalopram and group psychotherapy in breast cancer patients: A randomized clinical trial
Surgery
Surgery
Original Research
Original Research
<p><strong> </strong><strong> Background: </strong>Depression is a common psychiatric disorder in breast cancer patients. This study was designed to evaluate the clinical efficacy of group psychotherapy on breast cancer patients with depressive disorder who took citalopram.<br>
<strong> Methods:</strong> This clinical trial was conducted on 40 breast cancer patients with depressive disorder. The control group received citalopram 20-40 mg/ day for 12 weeks and the intervention group participated in 8 sessions of group psychotherapy in addition to the same dose of citalopram. At the baseline and 3, 6, and 12 weeks after treatment, patients were followed- up. Treatment outcomes and quality of life were compared between the 2 groups.<br>
<strong> Results:</strong> Overall, the depression score of Hospital Anxiety and Depression Scale (HADS) at baseline with the mean of 11.6±1.6 was signed in the range of clinical depression and after intervention it declined to 8.8±3.6 (in the 3rd week), 7.1±3.9 (6th week), and 5.9±4.5 (12th week). Furthermore, HADS anxiety score at baseline with the mean of 12.6±2.6 was signed in the range of clinical anxiety and after intervention it declined to 9.1±3.0, 7.3±4.1, and 6.0±4.0, respectively. This improvement was significantly more in the combined therapy intervention group (p<0.001). The mean score of quality of life based on WHO QOL-BREF questionnaire increased by 1.85 fold in the case group, improved from 44.09 to 81.70, while the slight change was observed in the control group (p<0.001). During the treatment, no significant adverse drug event was observed in the 2 groups (p>0.05).<br>
<strong> Conclusion:</strong> Group psychotherapy has a significant effect on improving depression, anxiety, and quality of life in breast cancer patients.<br>
</p>
Breast cancer, Depression, Anxiety, Citalopram, Group psychotherapy
394
399
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-3401-1&slc_lang=en&sid=1
Novin
Nikbakhsh
novinsu@hotmail.com
200319475328460039250
200319475328460039250
No
Cancer Research Center, Babol University of Medical Sciences, Babol, Iran.
Sussan
Moudi
sussan.mouodi@gmail.com
200319475328460039251
200319475328460039251
Yes
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Sara
Alvarzandi
sarazand87@yahoo.com
200319475328460039252
200319475328460039252
No
Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Maede
Niazifar
mae.nzf@gmail.com
200319475328460039253
200319475328460039253
No
Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Nazila
Farnoush
nazilafarnoush@gmail.com
200319475328460039254
200319475328460039254
No
Department of Surgery, Babol University of Medical Sciences, Babol, Iran.
Ali
Bijani
alibijani@yahoo.com
200319475328460039255
200319475328460039255
No
SDH Research Center, Babol University of Medical Sciences, Babol, Iran.
Marjan
Moudi
marjan_mouodi@yahoo.com
200319475328460039256
200319475328460039256
No
Department of Internal Medicine, Babol University of Medical Sciences, Babol, Iran.