Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1388
2
1
gregorian
2009
5
1
23
1
online
1
fulltext
en
Two cases of pseudoxanthoma elasticum with renal involvement
Internal Medicine
Internal Medicine
case report
case report
<p> <strong> Abstract </strong></p><p> Pseudoxanthoma elasticum is a rare, hereditary, multisystemic disease affecting </p><p> the skin, eye, and cardiovascular system. Renal involvement is uncommon. </p><p> We describe two cases of pseudoxanthoma elasticum (PXE) in two women with </p><p> distinctive skin lesions and nephrocalcinosis that renal ultrasonography showed a </p><p> characteristic pattern of dotted increased echogenicity in the corticomedullary junction. </p><p> One of them had IgA nephropathy that was proven by kidney biopsy. Skin biopsy </p><p> and fundus examination confirmed the diagnosis. Early diagnosis of PXE is important </p><p> for minimizing systematic complications and informing the other family </p><p> members through genetic counseling. Our case with PXE and IgA nephropathy is the </p><p> first case report. </p>
Pseudoxanthoma Elasticum - nephrotic syndrome - IgA nephropathy
53
57
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-41&slc_lang=en&sid=1
Esmat
Ghanei
dr-e-ghanei@yahoo.com
20031947532846001783
20031947532846001783
Yes
Department of Internal Medicine of Shohada Hospital Shahid Beheshti University of Medical Sciences
Seyyed Mohammad
Homayouni
20031947532846001784
20031947532846001784
No
,Department of Internal Medicine of Shohada Hospital. Shahid Beheshti University of Medical Sciences,
Alireza
Nasrollahi
20031947532846001785
20031947532846001785
No
,Department of Internal Medicine of Shohada Hospital. Shahid Beheshti University of Medical Sciences,