Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1396
11
1
gregorian
2018
2
1
32
1
online
1
fulltext
en
Depressive symptoms among metabolically healthy and unhealthy overweight/obese individuals: a comparative study
Psychiatry
Psychiatry
Original Research
Original Research
<strong>Background: </strong>Although a growing body of evidence suggests an association between obesity and depressive disorder, the association remains inconclusive. Metabolically healthy obese (MHO) phenotype, defined by favorable lipid profile, and normal insulin sensitivity, blood pressure, may be considered as a possible explanation for these inconsistencies. Accordingly, this study aimed to compare depression score among metabolic unhealthy obese (MUO) and age- and sex-matched healthy controls.<br>
<strong> Methods:</strong> In this comparative study including 157 Iranian adults, we assigned participants into three groups (non-obese metabolic healthy group, MHO and MUO) according to the BMI cutoff and MetS criteria. Depressive symptoms were assessed by Beck Depression Inventory. Analysis was done using SPSS version 14.0. All variables are expressed as means ± SD. One-way ANOVA and Multiple linear regression were used for data analysis.<br>
<strong>Results:</strong> After adjustment for sex, marital status and educational level, MUO participants had significantly higher Beck depression score (P= 0.036) compared to MHO and non-obese metabolic healthy groups. After adjustment for demographic variables, there was a significant association between waist circumference (β = 0.142, p=0.023), BMI (β= 0.347, p= 0.037), FBS (β= 0.096, p< 0.001), and the number of MetS components (β= 1.71, p= 0.002) with depression score.<br>
<strong> Conclusion:</strong> MHO was a benign phenotype in relation to depression.<br>
<br>
Depressive symptom, MetS, Obesity
549
552
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-2083-4&slc_lang=en&sid=1
Somaye
Yosaee
s_yousai2006@yahoo.com
200319475328460041196
200319475328460041196
No
School of Public Health, Iran University of Medical Sciences, Tehran & School of Health, Larestan University of Medical Sciences, Larestan, Iran
Kurosh
Djafarian
kdjafarian@tums.ac.ir
200319475328460041197
200319475328460041197
No
School of Nutrition Sciences, Tehran University of Medical Sciences, Tehran, Iran
Alireza
Esteghamati
esteghamati@tums.ac.ir
200319475328460041198
200319475328460041198
No
Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
Abbas
Motevalian
amotevalian@yahoo.com
200319475328460041199
200319475328460041199
No
School of Public Health, Iran University of Medical Sciences, Tehran, Iran
Farzad
Shidfar
farzadshidfar@yahoo.com
200319475328460041200
200319475328460041200
No
Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology & Metabolism, & School of Public Health, Iran University of Medical Sciences, Tehran, Iran
Mehdi
Tehrani-Doost
tehranid@sina.tums.ac.ir
200319475328460041201
0002-9134-7178, Esteghamati A, 0000-0001-5114-3982
No
Department of Psychiatry School of Medicine, Roozbeh Psychiatry Hospital Tehran University of Medical Sciences, Tehran, Iran
Shima
Jazayeri
sh_jaz@yahoo.com
200319475328460041202
200319475328460041202
Yes
Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology & Metabolism, & School of Public Health, Iran University of Medical Sciences, Tehran, Iran