Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1399
10
1
gregorian
2021
1
1
35
1
online
1
fulltext
en
Risk factors of erosive esophagitis and barrett’s esophagus in patients with reflux symptoms
Gastroenterology
Gastroenterology
Original Research
Original Research
<strong>Background: </strong>Gastroesophageal reflux disease (GERD) is a prevalent condition. Erosive esophagitis (EE) and Barrett’s esophagus (BE) are the two important complications of GERD. We aimed to study the prevalence of EE and BE in a group of Patients with reflux symptoms who were referred for endoscopy. The relationship between reflux symptoms and endoscopic findings was also examined.<br>
<strong>Methods:</strong> We enrolled 139 consecutive patients with characteristic symptoms of GERD. Demographic and clinical characteristics of the patients including duration and severity of reflux symptoms, were recorded. Endoscopic findings of EE were identified and classified according to the Los Angeles classification, while BE was confirmed by histopathology examination. The Fisher’s exact test and the two-sample 𝑡-test were used to test the association of esophageal lesions (BE and/or EE) with the patients' clinical and endoscopic data.<br>
<strong>Results:</strong> Forty seven and 13 patients were found to have EE and BE, respectively. Multivariate analysis showed that older age (p=0.001) and hiatal hernia (p=0.004) was significantly related risk factors for erosive esophagitis and BE. While an increase in BMI (p=0.004) was related to EE, patients with BE were more likely to have severe reflux symptoms than others (p=0.002).<br>
<strong>Conclusion:</strong> In patients with GERD, the presence of hiatal hernia may be strong risk factor for erosive esophagitis and BE, as does older age. For Barrett’s esophagus, severe reflux symptoms are more likely.
Barrett’s esophagus, Reflex esophagitis
586
590
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-5957-1&slc_lang=en&sid=1
Rabah
Asreah
rabahasreah@comed.uobaghdad.edu.iq
200319475328460063164
200319475328460063164
Yes
Department of Medicine, College of Medicine, University of Baghdad, Baghdad, Iraq
Ali
Abdullhameed
alawi3838@gmail.Com
200319475328460063165
200319475328460063165
No
Department of Medicine, Baghdad Teaching Hospital, Baghdad, Iraq