Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1379
11
1
gregorian
2001
2
1
14
4
online
1
fulltext
en
ENVIRONMENTAL FACTORS AND POLYCYSTIC OVARIES
Gynecology & Obstetrics
Gynecology & Obstetrics
Original Research
Original Research
This study was designed to investigate the effect of environmental factors on
the appearance of polycystic ovaries (PCO) during the first two decades of life.
Ninety-four female-female twins who underwent a transabdominal ultrasound
at the Royal Hospital for Women were sent a questionnaire asking about their
birth details, feeding history as a baby, childhood illnesses and vaccination as
well as exercise patterns. Seventy-seven subjects returned the questionnaire. All
of the variables were studied in two groups of subjects those with ultrasound
evidence of polycystic ovaries (US-PCO, n= 37) and those with normal ovaries
(US-normal, n= 40). The data were also analyzed in a group of scan-discordant
twins (7 pairs) in whom one of the twins had US-PCO and the co-twin had normal
ovaries.
Analyzing the data from the whole database suggested that US-PCO subjects
had lower birth weight compared to US-normals. Vaccination against mumps
was also found to be significantly higher in the US-PCO group compared with
US-normals. Matched results for scan-discordant twins did not confirm these results.
Other environmental variables such as feeding history, type of delivery,
birth order and physical activity during the first 20 years of age did not seem to
have any significant influence on the prevalence of PCO. No significant difference
was found in childhood illnesses between the groups.
In conclusion, this study examined the effect of some environmental factors during
childhood and early adulthood. Analyzing the whole database and scan-discordant
twins failed to show any particular environmental factor associated with PCO.
Polycystic ovary, Twin study, Environmental factors.
337
342
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-287&slc_lang=en&sid=1
SHAYESTEH
JAHANFAR
20031947532846004273
20031947532846004273
Yes
From the School of Obstetrics and Gynecology, Royal Hospital for Women, Sydney, Australia
JOHNA
EDEN
20031947532846004274
20031947532846004274
No
N. S. W. University