Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1378
11
1
gregorian
2000
2
1
13
4
online
1
fulltext
en
EFFECT OF INTRAOCULAR POVIDONE-IODINE SOLUTION IN PREVENTION OF BACTERIAL ENDOPHTHALMITIS IN A RABBIT MODEL
Ophthalmology
Ophthalmology
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
In order to determine the effects of intraocular 0.05% povidone-iodine
preparation in the prevention of bacterial endophthalmitis in a rabbit model, 28
albino rabbits were randomly assigned to 4 equal groups. A concentration of 5x
108 organisms (0.03 mL) in logarithmic growth phase of S. epidermidis, S. aureus,
Proteus mirabilis and Pseudomonas aeruginosa, were injected separately in the
anterior chamber of right and left eyes of each group. Then 0.03 mL of 0.05%
povidone-iodine solution was injected in the left eyes. Eye examinations were
performed with a slit-lamp daily for two weeks following injection.
From 28 eyes injected with bacteria and povidone-iodine, 20 cases did not
develop endophthalrnitis, one developed mild, one developed moderate, and 6
developed severe endophthalmitis. In comparison, from 28 eyes injected with
bacteria and balanced salt solution, 9 cases developed mild, 10 developed
moderate and 9 developed severe endophthalmitis (p<0.00 1) .
Povidone-iodine solution is therefore effective in prevention of bacterial
endophthalmitis, although its efficacy has a direct relationship to the bacteria type
and species.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-380&slc_lang=en&sid=1
HA
SHAHRIARI
20031947532846004561
20031947532846004561
Yes
From the Dept. of Ophthalmology, Zahedan University of Medical Sciences, Dr Shariati Ave, Zahedan, 98134, I.R. Iran.
A
SALEHI
20031947532846004562
20031947532846004562
No