Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1377
11
1
gregorian
1999
2
1
12
4
online
1
fulltext
en
ANTI-TETANUS IMMUNOGLOBULIN ISOTYPES IN WOMEN OF CHILDBEARING AGE
Immunology
Immunology
Original Research
Original Research
Neonatal tetanus (NT) is a leading cause of neonatal mortality in many parts of
the world. Tetanus is a vaccine-preventable disease and is second only to measles
worldwide as a cause of childhood mortality. In this study the various irnrnunoglobulin
classes of anti-tetanus antibody in the sera of 105 Iranian women of childbearing age
(13-45 years) were titrated by enzyme linked immunosorbent assay (ELISA). Our
results demonstrate that the majority of women (96.29%) had protective anti-tetanus
toxoid antibody. All women were negative for 19E. 92.39%, 91.43% and 80.96% of
women were found to be positive for IgG, IgA and IgM, respectively. Therefore, with
respect to lack of protective anti-tetanus antibody in a minority of women, our results
suggest that this group might be at risk of tetanus disease and if they get pregnant,
need to be vaccinated against tetanus in order to produce sufficient Ab for their own
protection and to provide their fetuses with anti-tetanus antibody.
Antibody, tetanus, mother, fetus.
319
323
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-432&slc_lang=en&sid=1
K
AHMADI
20031947532846004715
20031947532846004715
Yes
From the Department of Immunology, Baghiatollah University of Medical Sciences, Tehran
MB
ESLAMI
20031947532846004716
20031947532846004716
No
the School of Public Health, Tehran University of Medical Sciences, Tehran, I.R. Iran.