Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1377
8
1
gregorian
1998
11
1
12
3
online
1
fulltext
en
ALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
Oncology
Oncology
Original Research
Original Research
Eighteen patients, twelve men and six women, with aplastic anemia underwent
allogenic bone marrow transplantation (BMT) from HLA-matched siblings during
the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with
or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin
(ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis,
respectively. Eleven patients are alive (61 %) and seven (39%) died. Twelve patients
developed acute GVHD. We found an inverse relationship between the incidence of
acute GVHD and the number of units of transfused packed cells and platelets before
BMT (p<O.OI). We could not find an association between the incidence of chronic
GVHD and age or a positive history of acute GVHD. The time of cellular recovery
(WBC> 1000, PLT> 100000) after BMT was inversely related to the total number of
cells transplanted (p<0.05).
Aplastic anemia, Bone marrow transplantation
217
220
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-448&slc_lang=en&sid=1
P
NASSERI
20031947532846004756
20031947532846004756
Yes
From the BMT Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
A
GHAVAMZADEH
20031947532846004757
20031947532846004757
No
M
JAHANI
20031947532846004758
20031947532846004758
No
A
KHODABANDEH
20031947532846004759
20031947532846004759
No
I
BAYBORDI
20031947532846004760
20031947532846004760
No
M
MOHYEDDIN
20031947532846004761
20031947532846004761
No
G
GHAHREMANI
20031947532846004762
20031947532846004762
No