eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
279
280
article
THE STUDY OF CLASS I HLA TYPES IN PATIENTS WITH ULCERATIVE COLITIS AND ITS COMPARISON WITH HEALTHY PERSONS
MOHAMMAD EBRAIDM EBRAHIMZADEH
ebrahimzadeh_me@yahoo.com
1
Department of Clinical Biochemistry, Faculty of Medical Sciences, Tabriz University of Medical Sciences,
http://mjiri.iums.ac.ir/article-1-591-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
275
278
article
PRIMARY LIPOSARCOMA OF THE STOMACH: A RARE MESENCHYMAL TUMOR
NOUSHIN AFSHAR MOGHADDAM
afsharmoghadam@med.mui.ac.ir
1
MANSOUR SAFAEI
2
Pathology Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, l.R. Iran.
Gastric liposarcoma is very rare such that only a few cases have been reported to
date.
We present a case of a 62 - year - old diabetic man who presented with epigastric
pain, vomiting, constipation and melena. The physical examination was unremarkable.
By computed tomography (CT), a large mass with low attenuation value was
seen in the left abdominal cavity. Histologic examination of a gastric biopsy was
nondiagnostic. The patient underwent subtotal gastrectomy. On microscopic examination,
the tumor showed features of a benign lipoma but with a distinctive capillary network
and dense fibrotic areas. In immunohistochemial staining, positive S 100 and negative
CD 117 reactions were seen, and less than 1 % Ki67 positive cells could be found.
These findings suggested a highly differentiated gastric liposarcoma.
http://mjiri.iums.ac.ir/article-1-590-en.pdf
Gastric
Mass
Lipoma
Well differentiated liposarcoma
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
271
274
article
CELIAC ARTERY ANEURYSM: A NEW METHOD IN THE MANAGEMENT OF AN OLD PROBLEM
M.R KALANTAR MOTAMEDI
kalmotam@yahoo.com
1
F AGHAEE MEYBODI
2
F MALEKPOUR GHORBANI
3
S SASANI
4
Department of Trauma and Vascular Surgery, Shohada Tajrish Medical Center, Shahid Beheshti
Celiac artery aneurysm is a rare visceral aneurysm, comparising only 4 % of them.
In this article, an innovative surgical method is presented for the treatment o f such
aneurysms.
A 53 year old female referred to our center with epigastric pain and a mass in the
region, which was diagnosed as a case of celiac artery aneurysm by using different
imaging techniques. During the operation, according to the firm adherence of the mass
to the aorta and a short celiac artery stump, we omitted aortic clamping and took
control of entrance and exit sites to the aneurysm using a Foley and a Fogarthy catheter
respectively. Using the normal part of the aneurysm's wall, the damaged part was trimmed
and patched with a PTFE vascular patch.
The patient was discharged satisfactorily in two days and did not have any problem
in her follow-up. There was no need for extracorporeal oxygenation and total time
of the procedure and vascularization was shortened.
This surgical method obviates extracorporeal oxygenation due to reduction of
aortic clamping time. Total procedure time and revascularization time will be shortened.
It is proposed as an alternate method in cases when a short stump restricts proximal
clamping, and also since there is little risk of renal and visceral ischemia.
http://mjiri.iums.ac.ir/article-1-589-en.pdf
Celiac artery
Visceral aneurysm
Clamping time
PTFE patch repair
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
267
270
article
PREVALENCE OF ROTAVIRALDIARRHEA IN AHVAZ ABUZAR HOSPITAL
A.R SAMARBAF-ZADEH
samarbafa@yahoo.com
1
E MAZAHERI-TEHRANI
2
Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapoor University of Medical
Introduction: In developing countries, rotaviral diarrhea is the cause of death of
many children, and is the main etiology of gastroenteritis in children under 2 years old.
Determination of the prevalence of rotaviral infection can reveal the impact of this infection
in this group of the population and provides clues as to the strategies for prevention
and treatment protocols for children suffering from diarrhea.
The aim of this study was to determine the prevalence of group A rotavirus in
diarrheic children in Ahvaz, Iran.
Methods: For this purpose, 200 stool samples were collected from diarrheic
children under 2 years old who were referred to Ahvaz Abuzar Hospital. The samples
were examined by electron microscope and the electropherotype of extracted RNA of
the virus were also studied.
Results: The results showed that 59 samples (29.5%) were rotavirus positive.
Conclusion: These results suggest that the prevalence of this virus in diarrheic
children is moderately high in comparison with some reports from other developing
countries.
http://mjiri.iums.ac.ir/article-1-587-en.pdf
Rotavirus
EM
Electropherotype
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
255
265
article
IDENTIFICATION, ISOLATION, CLONING AND SEQUENCING APARTIALANNEXIN GENE FROM AUREOBASIDIUM PULLULANS
A KAZEMI
hassan5628@yahoo.com
1
G.D ROBSON
2
D.W DENNING
3
Immunology and Parasitology Department , School of Medicine, Tabriz University of Medical Sciences, Tabriz, I.R. Iran
Background and Objectives: Annexin is the common name for genes and proteins
that were identified as calcium-dependent phospholipid-binding proteins. Recently
a more complex set of functions has been recognized for this superfamily of proteins
including in vesicle trafficking, cell division, apoptosis, calcium signalling, mineralization,
crystal nucleation inside the extracellular organelles-matrix vesicles (MY s) and growth
regulation.
Methods: In the present work Aureobasidium pullulans strain PRAFS8 genomic
DNA was extracted. Using designed primers from a highly conserved region of
annexin genes of Aspergillus Jumigatus and Aspergillus niger a 800 bp PCR product
was obtained from degenerated PCR. The 800 bp PCR product was gel purified and
cloned into E. coli using the suitable plasmid and standard cloning procedures. From
grown transformed E. coli, plasmid was extracted and the presence of expected insert
in the plasmid, was confirmed by digestion of plasmid by Eco RI restriction enzyme.
Results: Gel purified 800 bp band was sequenced and submitted at NCBI gene
bank with accession No.: AY848856. A phylogenetic tree for obtained partial gene of
annexin was drawn using bioinformatic software in order to understand the evolutionary
relationship of annexin genes between some microrganisms. Also southern analysis
of800 bp PCR product using digoxigenin (DIG) labeled probe demonstrated the probability
of two copies of annexin genes existence in the A. pullulans genome.
Conclusion: This study for the first time presented the presence of annexin gene
in yeast-like fungi and this result is important due to the existence of this superfamily of
genes in moulds but not in yeasts.
We emphasize for future additional work to clone and sequence the full length of
annexin gene(s) from A. pullulans and also additional studies for this gene expression
and annexin mRNA transcription to understand the effective factors for expression of
annexin.
http://mjiri.iums.ac.ir/article-1-584-en.pdf
Annexin
Gene
Sequencing
Aureobasidium pullulans
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
251
254
article
SYNERGISM BETWEEN 1-MEGAHERTZ THERAPEUTIC ULTRASOUND PL US CEFTAZ-IDIME ON GROWTH OF PSEUDOMONASAERUGINOSA
NASIM KASHEF
kashefn@modares.ac.ir
1
QORBAN BEHZADIAN NEJAD
2
Department of Bacteriology and the 2Department of Medical Physics, Tarbiat Modares
Objective: The effect of ceftazidime on Pseudomonas aeruginosa, with or without
application of 1 MHz therapeutic ultrasound, was studied.
Method: An aqueous suspension of microorganisms in a sterile, sealed plate was
placed in an ultrasonic tank operating at 1 MHz. Different power outputs were used.
After desired time of exposure to the ultrasound, each sample was plated separately
and after incubation, the number of colonies was counted.
Results: Results showed that ultrasound in combination with sMICs of ceftazidime
was much more lethal to this bacterium than either of the treatments alone. The mechanism
by which ultrasound enhances antibiotic action is due to the induction of uptake of
antibiotic by perturbing or stressing the membrane.
Conclusion: This application of ultrasound may be useful for expanding the number
of drugs available for treating localized infections by rendering bacteria susceptible
to normally ineffective antibiotics.
http://mjiri.iums.ac.ir/article-1-583-en.pdf
Ceftazidime
Pseudomonas aeruginosa
Ultrasound
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
247
250
article
EVALUATION OF PATIENTS WITH HEMIPLEGIC MIGRAINE IN MACKENZIE HEADACHE CLINIC
KAVIAN GHANDEHARI
kavianghandehari@yahoo.com
1
ASHFAQ SHUAIB
2
Department of Neurology, Southern Khorasan University of Medical Sciences, Birjand, Iran
Background: The sporadic type of Hemiplegic Migraine (HM) is sometimes
observed among migrainous patients (MP) and mimics ischemic strokes.
Methods: In an evaluation of two-hundred consecutive adult MP in the Mackenzie
headache clinic, Canada during 2004 , 9% of the patients met the criteria established
by the International Headache Society for sporadic HM. Female to male sex ratio,
family history of migraine, frequency of epileptic seizures, migraine status and migraine
aura without headache were investigated in the HM group and compared with other
MP. The relationship between side of hemiplegia and distribution of head pain was also
evaluated.
Results: All of these clinical dimensions were significantly more common in the
HM group than in the other MP. All of the patients with HM had other types of aura.
Hemiplegia was often ipsilateral to the side of the headache. These results highlight the
importance of documenting the side of hemiplegia in relation to the headache side, as
well as determining the history of seizures in HM patients.
Conclusion: This study supports the argument that migraine is a disease which
may appear with different or mixed presentations in each episode.
http://mjiri.iums.ac.ir/article-1-581-en.pdf
Hemiplegic
Migraine
Sporadic
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
241
245
article
CEREBROSPINAL FLUID FINDINGS IN NEONATAL BACTERIAL MENINGITIS
Ali ZAMANI
1
FATEMEH ZAMANI
2
Pediatric Department, Vali-Asr Hospital, Valises Reproductive Health Research Center, Tehran, I.R. Iran.
Background : Meningitis is more common during the neonatal period than other
periods of life and has a prevalence of one in 1000 live births. The similarity of its
clinical manifestations with other infectious diseases makes it difficult to diagnose. The
aim of the current study was to determine the relationship between age, sex, clinical
signs and symptoms and laboratory test results of newborns in which bacterial meningitis
had been confirmed by positive CSF culture.
Methods: This cross-sectional study was performed by a non-randomized simple
sampling method, in which the medical files of neonates hospitalized between March
1994 and Oct. 1999 were reviewed.
Results: A total of294 files (16 boys, 127 girls 54 preterm, 240 full-term infants)
were reviewed. Fifteen newborns (8 girls, 7 boys) had positive CSF culture
results. A significant statistical relationship was not found between sex and pre-term
cases with meningitis. The most common results in newborns with positive CSF culture
were poor feeding, lethargy and hyperthermia, followed by seizures, jitteriness, hypothermia
and vomiting. Blood culture was positive in only 6 (40%) of the 15 neonates
with positive CSF cultures. Leukocytosis (3 cases, 20%), thrombocytopenia (2 cases,
13 .3%) and positive direct CSF smear (9 cases, 60%) were also present. Group B
Streptococcus (GBS), E. coli and gram-negative bacteria were the leading causes of
neonatal sepsis and meningitis. A significant difference was found in the WBC count,
CSF protein and glucose levels with bacterial meningitis. A significant relationship was
also found to exist between CSF glucose-simultaneous blood glucose ratio and neonatal
meningitis.
Conclusion: There was a significant difference between CSF protein and glucose,
WBC count and bacterial meningitis. A significant relationship was also found
between CSF and blood glucose ratio ( CG ) and neonatal bacterial meningitis
http://mjiri.iums.ac.ir/article-1-580-en.pdf
Neonatal
meningitis
CSF
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
237
240
article
LAPAROSCOPIC OVARIAN DRILLING INCLOMIPHENE RESISTANT PCO PATIENTS: A PREFERRED METHOD OF TREATMENT
J ZOLGHADRI
jzolghad@yahoo.com
1
S MOTAZEDIAN
2
S DEHBASHI
3
Z TAVANA
4
Gynecology Endoscopy Ward, Shiraz University of Medical Sciences, Shiraz, Iran.
Objective: To determine the efficacy of ovarian drilling in PCO patients who
failed to achieve pregnancy with medical treatment.
Methods and Main Results: 75 patients with a diagnosis of PCO of whom
48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene
resistant. The other methods like bromocriptin, gonadotropins, GnRH -a and
metformin had been given to these patients for infertility treatment without benefit. After
ovarian drilling, pregnancy was achieved in 41 patients (54.6%), 30(40%) in group I
(primary infertile group) and 11 (14.6%) in group II (secondary infertile group). During
the operation adhesiolysis was necessary in 14( 18.6%) and removal of endometriotic
lesions was indicated in 5(6.6%) in both groups.
Conclusion: Ovarian drilling is an ideal technique in PCO patients with failure of
medical treatment, considering the benefit of also performing other necessary surgical
interventions.
http://mjiri.iums.ac.ir/article-1-579-en.pdf
Clomiphene resistant PCO- laparoscopic ovarian cauterization
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
231
236
article
EVALUATION OF CRANIALIZATION TECHNIQUE IN T HE TREATMENT OF FRONTAL SINUS FRACTU RES
I LOTFINIA
1
G SHOKOUHI
2
F SALEHPOOR
3
S BABOLI
4
J TOTONGEE
5
Departments of Neurosurgery and Otolaryngology, Tabriz University 0f Medical Sciences,
Frontal sinus fractures are of surgical importance because of the microbial flora
covering the frontal air sinus and it's proximity with the duramater and brain. There is an
increased risk of meningitis when fracture of the posterior wall of the frontal sinus is
associated with a dural tear. In this condition, communication occurs between the contaminated
space of the air sinus and the intracranial space, which may be concurrent
with cerebrospinal fluid (CSF) leakage.
Non-depressed fracture of the posterior wall of the frontal sinus per se generally
doesn't warrant surgical repair, but in some cases when conservative therapy fails to
manage CSF leakage and when there is severe injury to the posterior wall of the sinus
or to the sinus drainage duct, surgical treatment is warranted.
Cranialization is the surgical procedure for such patients in whom communication
between the frontal air sinus and outside space is cut off and the air sinus space is
integrated with the intracranial space. In this study, we evaluated 29 patients with frontal
region fracture who underwent cranialization performed by a single surgery team. Of
these patients, 89.7% were male and 10.3 % were female. The most common cause of
injury was found to be vehicle accident trauma (65.5%). These patients were also seen
to have concurrent iJ1iuries involving the brain parenchyma, cranial nerves (II and III),
and pneumocephalus. Post-operative complications included rhinorrhea, CSF leakage
from the wound, meningitis and superficial infection of the site of surgery. All these
complications improved with conservative therapy.
In general, in cases of severe injuries to the posterior wall of the frontal air sinus
with nasofrontal duct injury, cranialization is an appropriate procedure. In these patients,
in order to reduce complications it is essential that particular attention be paid to
the repair of the damaged duramater and to the closure of the nasofrontal duct.
http://mjiri.iums.ac.ir/article-1-578-en.pdf
Cranialization
Frontal sinus
Traumatic rhinorrhea.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
223
230
article
ANGIOPLASTY AND STENTING OF CAROTID ARTERY STENOSIS WITH EMBOLIC PROTECTION DEVICES
ALI MOHAMMAD HAJI ZEINALI
ali_ zeinali_cardio@yahoo.com
1
DAVOOD KAZEMI SALEH
2
Interventional Department of Tehran Heart Center; Tehran University of Medical Sciences, Tehran, Iran.
Background: Carotid artery stenting (CAS) has recently been recommended as
an alternative to carotid endarterectomy (CEA) by some clinicians.
Objective: This study was designed to evaluate the success rate and in-hospital
and 30-day adverse events in our first experiences in Iran for CAS with protection
devices, to document our results and guide further use of CAS.
Methods: From December 2003 to December 2004 we performed 21 consecutive
CAS procedures. 16 were men and 5 were women with mean age of 62 years
(range 46-78 years). Indications for CAS included primary lesions in all patients with
stenosis >50% in symptomatic and stenosis >80% in asymptomatic patients.
Results: CAS was technically successful in a1l 21 patients. Mean severity of
stenosis before CAS was 85%+14% compared with 15%+10% after CAS. No
periprocedural death occurred. No in-hospital and 30-days minor or major stroke/
death was seen.
Conclusion: Our data suggest that percutaneous stenting of the carotid artery
when a cerebral protection device is used is feasible and effective but not without
technical difficulties and potential complications. We recommended CAS for high-risk
patients for carotid endarterectomy, but this technique has a learning curve for those
willing to perform the procedure with a low rate of complications.
http://mjiri.iums.ac.ir/article-1-577-en.pdf
Carotid Stenosis
Stenting
IRAN
Protection Device
Angioplasty
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
219
221
article
RELATIONSHIP BETWEEN KNEE MALALIGNMENT AND QANGLE WITH AGE AT ONSET OF DISEASE IN 260 CHONDROMALACIA PATELLA PATIENTS
I SALEHI
1
R JAMALI
2
S KHAZAELI
3
A JAMSHIDI
4
M AKBARIAN
5
F GHARIBDOOST
6
F DAVATCHI
7
Rheumatology Research Center, Amir A 'lam Hospital, Tehran University of Medical Sciences,
Background: Chondromalacia patella is the most common cause of mechanical
knee pain in young women. Q angle and knee alignment are important clinical parameters
for biomechanics of the patellofemoral joint.
Objective: To identify the prevalence of knee malalignment and to find out if there
is a correlation between knee mal alignment and Q angle with age at onset of disease.
Methods: All patients under 40 years old complaining of mechanical knee pain
with positive shrug sign and normal knee radiography who were referred to Amir A'lam
Rheumatology Clinic during the period of September 2000 to September 2002 were
included in this study. The patients were examined by a rheumatologist for measuring Q
angle and detection of knee malalignment. Age at onset of disease was defined as
initiation of knee pain according to the patient's history.
Results: The cases were 260 with 189 females. Prevalence of knee mal alignment
was 32.4%. The mean age at onset of disease was 22.8 ± 7.08 years. The mean age at
onset in patients with knee mal alignment (21.41 ± 5.66 years) was significantly lower
than the mean age at onset in those without knee malalignment (23.6 ± 7.43 years) (p=
0.002). There was a positive correlation between Q angle and age at onset of disease
(r=0.17,p= 0.006).
Conclusion: It seems reasonable to identify knee malalignment in chondromalacia
patella patients and perform proper management to postpone progression of disease.
There are many other factors that influence age at onset of disease, so further
investigation is recommended.
http://mjiri.iums.ac.ir/article-1-575-en.pdf
Q angle
Knee malalignment
Chondromalacia patella
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
213
217
article
A COMPARATIVE STUDY OF LATERAL APPROACH VERSUS P OSTERIOR APPROACH FOR THE SURGICAL TRE ATMENT OF SUPRACONDYLAR FRACTURES OF THE HUMERUS IN CHILDREN
A ENSAFDARAN
ensaf@yahoo.com
1
M.J EMAMI
2
M BORGHEI
3
Department of Orthopedic Surgery, Shiraz University of Medical Sciences, Shiraz, I.R. Iran
Background: Supracondylar fracture of the humerus is the second most common
fracture in children. For most cases closed reduction and percutaneous crossed
pinning is recommended. Those patients who had previously undergone an unsuccessful
closed reduction trial need open reduction and pin fixation, but the best surgical
approach is questionable. Most surgeons apply the technique of posterior or lateral
approach.
Methods: To compare the results of these two classical techniques, in a prospective
study, 40 pure closed noncomplicated supracondylar fractures of the humerus
(under 10 years old ), after failure of closed reduction, were randomized into 2
groups, 20 cases in each series, and operated by a single surgeon. The first group was
operated by posterior approach. There were 12 boys and 8 girls, with average age of
5 years (range 3-10). Their fractures were reduced and fixed by two crossed pins. The
second group was operated by lateral approach. There were 14 boys and 6 girls, with
average age of 6 years (range 4-10), whose fractures were reduced and fixed by two
lateral pins. Both groups were immobilized in a long arm posterior slab in 80 degrees of
elbow flexion. The sutures were removed after 2 weeks, and the pins were removed
after 3 weeks and active motion begun. Then after 6 months follow up, the results were
determined according to Lagrange - Rigault range of motion.
Results: In group 1: 70% (14 patients) were excellent, 20% (4 patients) good,
10% (2 patients) poor results. In group 2: 85% (17 patients) were excellent, 15% (3
patients) good, and no poor or bad results. There was a significant difference between
groups 1 and 2 (p<0.05) for post-operation range of motion. There was no deep
infection, myositis ossificans or compartment syndrome.
Conclusion: The lateral approach appears to provide good long-term functional
results.
http://mjiri.iums.ac.ir/article-1-574-en.pdf
Supracondylar fractures
Humerus
Surgical approach
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
207
211
article
EFFECTS OF EPIDURAL ANALGESI A WITH LOW-DOSE BUPIVACAINE AND FENTANYL ON THE PROGRESS OF LABOR AND MODE OF DELIVERY
S ATASHKHOII
siminatashkhoii@yahoo.com
1
M JAFARI SHOBEIRI
2
S NEGARGAR
3
Departments of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, l.R. Iran.
Background and Objective: Epidural analgesia (EA) has been used to relieve
labor pain in many obstetric units, yet controversy persists about its effect on progress
and outcome in labor. The purpose of the current study was to evaluate the effect of EA
on the rate of cervical dilation and myometrial contractility.
Methods: In a 6-month period, 36 women who received standardized EA were
matched with the next two delivering women of72 patients of the same parity who did
not receive EA. The outcome variables were uterine activity, rate of cervical dilation,
oxytocin therapy, and operative deliveries.
Results: Intermittent EA with bupivacaine and fentanyl did not result in a change
in myometrial contractility and the rate of cervical dilation. Oxytocin therapy was significantly
higher in the epidural group than in the nonepidural group (p0.0S).
Conclusion: After intermittent low-dose bupivacaine and fentanyl EA, myometrial
contractility and the ability of the uterus to dilate the cervix are maintained with
oxytocin. Despite prolongation of the second stage of labor, cesarean delivery was not
common in the epidural group.
http://mjiri.iums.ac.ir/article-1-573-en.pdf
Labor
Epidural analgesia
Bupivacaine
Fentanyl
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
201
206
article
PYOGENIC LIVER ABSCESS: REVIEW OF 54 CASES
MOHAMMAD GHAEMI
Ghaemi@mums.ac.ir
1
Department of Surgery, Imam Reza Hospital, Mashad University of
Background: Historically open surgical drainage has been the treatment of choice
for pyogenic liver abscess. The records of 54 patients with pyogenic liver abscess were
reviewed to determine whether earlier diagnosis with current imaging tests and definitive
treatment with antibiotics and aspiration drainage was an effective alternative to
surgery.
Methods: The clinical features, laboratory tests, imaging, and microbiologic findings,
management strategy and final outcome were studied.
Results: Twenty-nine patients were treated with broad-spectrum antibiotics and
diagnostic aspiration. Twenty-three (79%) recovered uneventfully, and six required
catheter or operative drainage. Twenty-three patients (including five who failed aspiration)
underwent drainage with percutaneusly placed catheters. Nineteen (83%) recovered,
four required open drainage, and of seven patients who required open drainage,
six recovered. One (2%) of the 54 patients died following failed aspiration and catheter
and surgical drainage. Four patients were successfully treated with antibiotics alone
without aspiration.
Conclusion: This study confirms that pyogenic liver abscess can be successfully
treated with broad spectrum antibiotics and aspiration or percutaneous catheter drainage.
Open surgical drainage is reserved for patients in whom treatment fails or who
require celiotomy for concurrent disease.
http://mjiri.iums.ac.ir/article-1-570-en.pdf
Liver
Abscess
Pyogenic
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
195
199
article
ENDOSCOPIC NODULAR GASTRITIS: AN INDICATOR OF HELICOBACTER PYLORI INFECTION IN CHILDREN
MEHRI NAJAFI SANI
mehrinajafi@hotmail.com
1
HAMID REZA KIANIFAR
2
AHMAD KHODADAD
3
MAHMOUD AHMADI
4
TAHEREH FALSAFI
5
GHOLAMREZA KHATAMI
6
the Departments of Pediatric Gastroenterology and Pathology, The Children's Medical Center;
Objective: To investigate the importance of endoscopic nodular gastritis associated
With Helicobacter pylori infection in children.
Methods: In this prospective study, 220 consecutive patients (age range 2 to 15
years, mean age 9. 02 ±3 .3 ), 118 of them males (53. 6%) underwent upper endoscopy
during evaluation of chronic abdominal pain. The appearance of nodular gastritis was
observed during endoscopy by the author. Culture, rapid urease test and staining were
carried out on gastric mucosal biopsies. With histological examination the presence of
Helicobacter pylori and the nature of inflammation was assessed.
Results: H. pylori infection was identified in 110 (50%) patients. Endoscopic
nodular gastritis was seen in 100 patients ( 45.5% ), and was significantly associated
with active chronic gastritis.
Nodularity in the stomach showed a sensitivity of72. 7% and a specificity of81.8%
and a ppv of 80% for the diagnosis of H. pylori infection and was observed in 80
(72. 7% of) H. pylori positive cases. Antral nodularity was associated with increasing
risk of infection with H. pylori (OR=12, 95% CI: 6.3-22.7).
Conclusion: Endoscopic findings of antral nodularity in children may suggest the
presence of H. pylori infection.
http://mjiri.iums.ac.ir/article-1-569-en.pdf
Helicobacter pylori
nodularity
gastritis
children
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2005-11
19
3
189
193
article
THE EFFECT OF ENDOMETRIAL PATTERN AND THICKNESS ON PREGNANCY RATE IN CONTROLLED OVARIAN HYPERSTIMULATION-INTRAUTERINE INSEMINATION
S ALBORZI
alborzis@sums.ac.ir
1
M MOMTAHAN
2
J ZOLGHADRI
3
M.E PARSANEZHAD
4
The Division of Infertility and Reproductive Endocrinology, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Objective: In order to evaluate the endometrium by ultrasound in patients undergoing
controlled ovarian hyperstimulation (COH) with clomiphene citrate (CC) and
human menopausal gonadotropin (HMG) with intrauterine insemination (IUI) to determine
the relationship between endometrial pattern and thickness on pregnancy rate
(PR).
Methods: In this prospective study, 108 infertile couples underwent COH with
CC and HMG. The patients were categorized in 4 groups according to etiology. Overall261
COH -IUI cycles with CC-HMG were evaluated. Thickness of the endometrium
was measured and its pattern was classified according to its echogenicity.
Results: In the homogenous group the pregnancy rate (PR)/cycle was 16. 7%,
and in the trilaminar group it was 15 .5%. This difference was not statistically significant
(p>0.05). The mean endometrial thickness in trilaminar and homogenous groups was
8.92+ 1.18 mm, and 8. 72+ 1.56 rnrn respectively. In cycles in which conception occurred,
the mean endometrial thickness was significantly higher in trilaminar and homogenous
groups (p<0.001).
In patients with a trilaminar pattern, the pregnancy was equal with those who had
a homogenous pattern. The endometrial thickness was a major factor in determining
PRs. There was no significant difference between PRs in cycles with trilaminar and
homogenous patterns according to the etiology of infertility
http://mjiri.iums.ac.ir/article-1-567-en.pdf
Transvaginal sonography
Endometrial pattern
Endometrial thickness
pregnancy rate