eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
243
243
article
RAMADAN AND CARDIOVASCULAR DRUG USE
MJ ZIBAEENEZHAD
1
O BARATI
2
From the Cardiovascular Research Centel; School of Medicine, Shiraz University of Medical Sciences, Shiraz,I.R. Iran
http://mjiri.iums.ac.ir/article-1-740-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
240
242
article
NEPHROPATHY CAUSED BY CHINESE HERBS IN IRAN
B EINOLLAHI
1
From the Department of Nephrology and Internal Medicine, Baghiatallah Medical Center, Tehran, l.R. Iran.
http://mjiri.iums.ac.ir/article-1-739-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
239
240
article
The RELATIONSHIP BETWEEN ABO BLOOD GROUPS AND SUSCEPTIBILITY TO DIARRHEA IN INFANTS DURING THE FIRST YEAR OF LIFE
JP MASOUMI
1
D YADEGARINIA
2
S MOZONI
3
From the Educational Development Center, Shaheed Beheshti University of Medical Sciences, Tehran, I.R. lran.
From the Educational Development Center, Shaheed Beheshti University of Medical Sciences, Tehran, I.R. lran.
From the Educational Development Center, Shaheed Beheshti University of Medical Sciences, Tehran, I.R. lran.
http://mjiri.iums.ac.ir/article-1-1625-en.pdf
Blood groups
Infantile diarrhea
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
235
237
article
LIPOSARCOMA OF THE CECUM
SA JALALI
1
From the Department of Surgery, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, I.R. Iran.
Liposarcoma of the digestive tract is very rare only a few cases of liposarcoma
of the stomach have been reported so far.
In this article a 29-year-old woman is presented with a history of long-standing
mid-abdominal pain and various treatments for anemia and peptic ulcer disease
which did not improve her symptoms until a barium-enema revealed a filling
defect in the cecum. Under laparotomy a lobulated lipoma-like tumor with
yellowish color was seen which measured 3x4cm. A right hemicolectomy was
performed. The pathology reported a liposarcoma of the cecum with no mesenteric
lymph node involvement. The patient is free of disease 1.5 years after surgery.
As far as we know, this is the first reported case of liposarcoma of the large
bowel in the world.
http://mjiri.iums.ac.ir/article-1-738-en.pdf
Liposarcoma
intestine.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
231
233
article
PROLONGED PARALYSIS AS AN UNUSUAL PRESENTATION OF RENAL TUBULAR ACIDOSIS
A DERAKHSHAN
1
GB HASHEMI
2
From the Division of Pediatric Nephrology, Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, I.R. Iran.
From the Division of Pediatric Nephrology, Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, I.R. Iran.
A case of renal tubular acidosis (RTA) who had gradual onset of paralysis of
lower extremities and persisted for a long time is presented. His primary workups
were mistaken for muscular dystrophy. Eventually, an abdominal ultrasonography
revealed small stones in both of the kidneys and his workup for the stones
were in favor of distal renal tubular acidosis and advanced rickets with hypokalemia.
He had a dramatic response to alkaline therapy. There are many reports of
periodic paralysis in RTA but no report of prolonged paralysis is found in the
literature.
http://mjiri.iums.ac.ir/article-1-1622-en.pdf
renal tubular acidosis
paralysis
rickets
hypokalemia
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
227
230
article
TUMOR ASSOCIATED OSTEOMALACIA IN NEUROFIBROMATOSIS: CASE REPORT AND LITERATURE REVIEW
M SOVEID
1
From the Department of Internal Medicine, Endocrinology and Metabolism Unit, Shiraz University of Medical Sciences, Shiraz, I.R. Iran.
The association of osteomalacia with neurofibromatosis is a very rare
entity. Here a 34 year old man, a known case of neurofibromatosis, is reported
who presented with bone pain, hypophosphatemia, rena] phosphorus wasting,
multiple Looser's pseudofractures, and low bone density. Treatment with high
dose calcitriol and phosphate resulted in temporary treatment. Permanent cure
was achieved after removal of two large superficial neurofibromas.
http://mjiri.iums.ac.ir/article-1-737-en.pdf
hypophosphatemia
osteomalacia
neurofibromatosis
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
221
225
article
THEORETICAL MODELS FOR DETERMINING THE VELOCITY OF ULTRASOUND IN BONE AND BONE SAMPLES
MB TAVAKOLI
1
From the Department of Medical Physics and Medical Engineering, School of Medicine, Isfahan
Currently available non-invasive clinical methods for diagnosing osteoporosis
are mainly associated with ionizing radiation. Ultrasonic assessment of bone disease
is a more recent technology. A theoretical explanation for the relationship between
ultrasonic parameters and bone structure is necessary.
Thus, two types of bone samples of perspex (HAP) and perspex-glass beads
were produced. Each type was made with a different fraction of constituents. The
ultrasonic properties of these samples were measured.
The results of velocity measurement showed rise of velocity in the samples
when the volume fraction of the HPA or glass beads increased with a different
trend.
A theoretical model for the velocity in a composite material was developed
and the results of the two samples were used to test the model. The results showed
a good agreement for the perspex-glass bead sample at different volume fraction,
while the agreement between perspex-HAP was not as good as the other sample.
http://mjiri.iums.ac.ir/article-1-736-en.pdf
ultrasound
velocity
attenuation
bone sample.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
213
220
article
ISOLATION OF MYELIN BASIC PROTEIN AND DETECTION OF I TS IMMUNOL\'OGICAL PROPERTIES
F MOKHTARI
1
S RAFEIE
2
E KEYHANI
3
From the Center of Researches for Biology and Microbiology, Institute of Standard and Industrial Research of Iran, Karaj,
theDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences,Tehran
the Institute of Biochemistry and Biophysics, Tehran University, Tehran, I.R. Iran.
Multiple sclerosis (MS) is an inflammatory disease of the central nervous
system of presumed autoimmune etiology. One of the best animal models of demyelinating
diseases is experimental autoimmune encephalomyelitis (EAE), which
can be induced in a variety of animals by injection of a target antigen such as
myelin basic protein (MBP). The immune responses against the target amino acids
cause tissue damages such as demyelination in the CNS.
In this study, after isolation of myelin basic protein from bovine cord, we
examined its purity and molecular weight by SDS-PAGE and in order to investigate
its immunological properties, two varieties of guinea pigs were injected with
different amounts of the isolated protein.
Clinical signs of EAE and also histological changes were detected. Delayed
type hypersensitivity, and anti-MBP antibodies to the isolated MBP were also
investigated. Another form of EAE which has been called chronic-relapsing EAE
(CR-EAE), was induced by injection of cord homogenate. EAE and CR-EAE are
the best models for MS investigations.
http://mjiri.iums.ac.ir/article-1-735-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
209
212
article
PATT ERN OF RESIS TANCE TO BETA-LACTAMS IN E.COLI ISOLATED FROM URINARY TRACT INFECTIONS IN IRAN
SM HOSSEINI-MAZINANI
hosseini@nrcgeb.ac.ir
1
H JAFAR-NEJAD
2
S GHANDILI
3
From the National Research Center for Genetic Engineering and Biotechnology, Tehran, l.R. Iran.
A total of 385 urine specimens from suspected urinary tract infections were
subjected to bacteriological analysis and susceptibility testing at a major university
hospital laboratory in Tehran.
A battery of eight beta-Iactam antibiotics, commonly prescribed in Iran, and
three third-generation cephalosporins (ceftazidime, ceftriaxone and ceftizoxime)
that are usually reserved for limited use in the hospital setting were tested against
E.coli urine isolates, using Kirby-Bauer disk diffusion method.
E. coli was the most common isolate from both the inpatient (37.8%) and
outpatient (30.5%) populations. The susceptibility testing revealed a high degree
of resistance to oxacillin, ampicillin, amoxycilIin, carbenicillin and cephradine.
Furthermore, a marked difference in the sensitivity/resistance ratio between the
inpatient and outpatient populations was observed.
The E.coli isolates exhibited the highest rate of resistance to oxacillin, ranging
from 49.4% in the outpatients to 81.6% in the inpatients. The frequency of the
isolate resistance to first-generation cephalosporins was less widespread. Despite
the absence of resistance to third-generation cephalosporins among the outpatient
isolates, a significant resistance to ceftazidime (9.6%) and ceftriaxone (8.8%)
was observed among the outpatient bacterial isolates. The susceptibility testing of
the E.coli isolates to a combination of amoxycillin and clavulanic acid revealed
6.9% resistance among outpatient and 12.5% among inpatient isolates.
These results are particularly significant in that this study was performed
immediately before the introduction of Co-amoxyclav to the Iranian drug market
and can be served as a basis for monitoring the spread of resistance to this drug in Iran.
http://mjiri.iums.ac.ir/article-1-734-en.pdf
antibiotic resistance
clavuianic acid
third-generation cephalosporins
urinary tract infection.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
205
208
article
REGRESSION OF LEFT VENTRICULAR HYPERTROPHY AFTER SUCCESSFUL RENAL TRANSPLANTATION AMONG UREMIC PATIENTS
SMH ADEL
h-adel@aums.ac.ir.h_adei41@hotmail.com.
1
H SHAHBAZIAN
2
From the Department of Cardiovascular Diseases and Kidney Transplantation, Golestan Hospital,Ahwaz University of Medical Sciences, Ahwaz, I.R. Iran.
Recognition of the natural history and responsible leading factors for regression
of left ventricular hypertrophy after successful renal transplantation are very
important. The aim of this study was to assess the regression of left ventricular
hypertrophy after successful renal transplantation among uremic patients. In this
study 27 uremic patients (18 males and 9 females) with an average age of 38.5
years were randomly selected. Left ventricular mass index (LVMI) was calculated
before and after renal transplantation at the beginning, and at 4, 6 and 8 months.
The means of LVMI before and after transplantation were 180±19.3 g/m2
and 133.8±16.8 g/m2 respectively (p<0.00l ). The means of regression after transplantation
at 0,4,6 and 8 months of follow up were 1919/m2, 157.3 g/m2, 147.8 g/
m2 and 138.8 g/m2 respectively. There was a significant difference between the
means of hemoglobin concentration and blood pressure before and after transplantation
(p<0.00l). For instance the means of hemoglobin concentration and
blood pressure was 7.2±0.4 and 13.1±0.7 g/dL, 154±6 / 97±4.4, and 135±6.3/
89±3.8 mmHg respectively.
This study showed that maximum left ventricular hypertrophy regression
occurred 4 months after transplantation, then decreased to a minimum level of
147.8 and 135.8 g/m2 at 6 and 8 months after transplantation respectively. Restoration
of hemoglobin concentration and blood pressure to normal levels may be
recognized as a main cause of left ventricular hypertrophy regression.
http://mjiri.iums.ac.ir/article-1-733-en.pdf
Left Ventricular Mass Index (LVMI)
Regression
Left Ventricular Hypertrophy(LVH)
Renal
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
199
203
article
NEURAL TUBE DEFECTS IN NEWBORNS IN THE SOUTH-EAST OF THE CASPIAN SEA BORDER (GORGAN, IRAN 1998-2000)
MJ GOLALIPOUR
mjgolalipour@yahoo.com
1
MA VAKILI
2
B ARYA
3
From the Department of Embryology and Histology Golestan University of Medical Sciences, Gorgan, I.R. Iran
the Department of Health Golestan University of Medical Sciences, Gorgan, I.R. Iran
the Department of Surgery, Golestan University of Medical Sciences, Gorgan, I.R. Iran
Neural tube defects (NTD) are one of the most important malformations of
newborns. The aim of this research is to determine the rates of NTD, anencephaly
and spina bifida cystica and the relations of these abnormalities to the factors
including sex, race, ethnicity, maternal age and familial marriage in the south-east
of the Caspian Sea border.
A three-year descriptive-analytic and cross-sectional study was carried out on
19545 newborns deliverd in Dezyani hospital in Gorgan during 1998-2000.
From the total sample population (19545), the NTD rate was 3.12 per 1000
deliveries. In males the rate was 2.49 per 1000, in females 3.79 per 1000, and the
female to male ratio was l.44: l. The rate of anencephaly and spina bifida was
l.25 per 1000 and l.74 per 1000 respectively. In regard to different races the
NTD rate was 7.48 per 1000,9.5 per 1000, and 2.35 per 1000 among Turkmans,
Sistanis and Parses, respectively.
It can be concluded that there is a higher rate of NTD in this region that may be
due to the race-ethnicity and the ecological variations.
http://mjiri.iums.ac.ir/article-1-732-en.pdf
neural tube defects
anencephaly
spina bifida cystica
Iran.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
193
197
article
THE EFFECT OF ELECTROSTIMULATION ON CALORIC-INDUCED NYSTAGMUS: A PRELIMINARY STUDY
M POURSADEGH
1
LV MOSTAAN
2
From the Department of Otorhinolaryngology, Imam Reza Hospital, Mashad University of Medical Sciences, Mashad, I.R. Iran
The objective of this study was to describe the role of electrical stimulation
in controlling peripheral vertigo.
In a prospective study on 13 healthy volunteers, nystagmus was induced with
caloric stimulation and the interval of nystagmus disappearance was recorded.
This time indicates the basal response of vestibular end-organ. After caloric irrigation,
pulsed signal was applied for each person through retroauricu1ar transcutaneous
electrodes and the interval of nystagmus disappearance was measured,
secondarily. In second examination on three new volunteers, simultaneous caloric
warm water irrigation in one ear and electrical induction in the other ear
were done for a long period.
There was a significant decrease in the duration of nystagmus with electrical
stimulation in the first stage (p<O.05), and in the second not only was there no
rotational feeling, but also at the end of irrigation no strong nystagmus was seen.
Regarding the results of this study we conclude that electrical stimulation
has a beneficial effect on vestibulosuppression.
http://mjiri.iums.ac.ir/article-1-731-en.pdf
caloric irrigation
galvanic stimulation
transcutaneous electrode
peripheral veltigo.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
189
191
article
AN INNOVATIVE SURGIC AL TECHNIQUE FOR CONTINUOUS SUTURING OF PROSTHESIS IN MITR AL VALVE REPL A CEMENT
M MASOUMI
aalihospital@kums.ac,ir
1
From Emam Ali Heart Center, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.
Mitral valve replacement (MVR) is usually performed in two methods of
running and interrupted suturing. In running method, the suturing of the valve is
usually with some traction on the annulus and also there is a risk of aortic valve
injury. This study was conducted to evaluate a new technique for suturing to avoid
these complications and decrease the time of cardiac arrest. One hundred and
seventy-seven cases undergoing isolated MVR or MVR with other valve replacements
were operated by the new method and compared with 77 cases of routine
method, as control group. The patients were followed up 1-4 years. In the control
group, one case of mortality occurred due to heart failure. In both groups one case
of late mortality was observed not related to surgical operation. No paravalvular
leakage or aortic valve injury was observed.
The highlights of this technique are the simplicity of operation, short
period of valve implantation and aortic clamp time, which indicated 6 and
11 minutes decrease in average time, respectively. This method is recommended
for all cases of rheumatic mitral valve disease, especially for those
having a small atrium.
http://mjiri.iums.ac.ir/article-1-730-en.pdf
heart valve prosthesis
mitral valve surgery.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
2003-02
16
4
183
187
article
THE DILEMMA OF HEMODYNAMIC INSTABILITY DURING INDUCTION OF ANESTHESIA: CAN MIDAZOLAM SERVE AS A SUITABLE SUBSTITUTE FOR THIOPENTONE?
Z HUSSAIN KHAN
1
H SABERI
2
MA BITARAF
3
Associate professor
Assistant professor
Assistant professor
Both midazolam and thiopental sodium are being used as induction agents
and for maintenance of anesthesia. In contrast to other benzodiazepines such
as diazepam, midazolam has a rapid onset of action and fast distribution and
causes few cardiovascular or respiratory effects. Being water soluble,
midazolam is also associated with a low incidence of venous irritation.
The purpose of this study was to see whether midazolam is a suitable
substitute for thiopental sodium as an induction agent. To compare the hemodynamic
changes associated with midazolam and thiopental sodium as induction
agents, this study was conducted in two groups each comprising of 30
patients. No significant hemodynamic changes regarding heart rate and blood
pressure could be noticed in the two groups (p<0.05). All patients in the
midazolam group exhibited anterograde amnesia but in the thiopental group,
20% of the patients had recall for operative events one hour after completion
of surgery.
To arrive at more conclusive results, preferably multi-center studies involving
large numbers of cases are recommended.
http://mjiri.iums.ac.ir/article-1-729-en.pdf
Hemodynamic instability
Induction of Anesthesia
Midazolam
Thiopental sodium.