eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
175
177
article
PRIMARY MALIGNANT LYMPHOMA OF THE BREAST
MANOOCHEHR M. LARI
1
ALI REZA TAVASSOLI
2
ABBAS TABATABAI YAZDI
3
SHIVA M. LARI
4
AHMAD KHOSRAVI
5
From the Department of Hematology, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran.
A case of primary malignant non-Hodgkin's lymphoma of the breast is
reported. This is the first well-documented case of breast lymphoma in our
institution and also in Iran. The diagnosis of primary breast lymphoma requires the
presence of lymphomatous infiltration in close ass, tissue in patients with neither previous lymphoma nor concurrent lymphoma in
another site. There is no definite clinical feature to distinguish patients with
lymphoma from those with malignant carcinoma. The median age at diagnosis is
reportedly in the mid-50's, but our patient was much younger.
http://mjiri.iums.ac.ir/article-1-1208-en.pdf
Breast lymphoma; Non-Hodgkin\'s lymphoma; Breast-incidence; Histiocytic lymphoma; Large cell
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
169
173
article
TWO CASES OF TYROSINEMIA TYPE II, AND ITS RARE OCCURRENCE IN TWO BROTHERS
MA JAVADI
1
SA MIRDEHGHAN
2
A BAGHERI
3
B EINOLLAHI
4
Y DOWLATI
5
From the Department of Ophthalmology, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran
the Center for Research and Education in Skin Disease and Leprosy, p.o. Box 14155-6383, Tehran, Islamic Republic of Iran
Tyrosinemia type II is a rare autosomal recessive disorder wich can present
itself with recurrent epithelial keratitis, hyperkeratotic skin lesions and mental
retardation.
This article reports the rare occurrence of this disease in both offsprings (two
brothers) of a family (consanguinous'marriage) who were managed with a lowprotein
diet and a special regimen.
http://mjiri.iums.ac.ir/article-1-1207-en.pdf
Richner-Hanhart syndrome
Tyrosinemia type II.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
165
167
article
A VERY RARE CASE OF FOREIGN BODY IN THE CORONARY ARTERY
FEREIDOON NOOHI
1
NADER GIVTAJ
2
MOHAMMADREZA SAIDI
3
From the Cardiovascular Research Center, Shahid Rajai Heart Hospital, Tehran, Islamic Republic of Iran.
A 56 year old man was admitted to our center for further evaluation of typical
chest pain of ten months' duration. Selective coronary angiography was done and
showed a sewing needle-like foreign body which was lying in very close proximity
to the anatomic location of the right coronary artery.
At operation two pieces of sewing needles were removed, one from the
coronary sinus and the other from the right coronary artery before the crux.
http://mjiri.iums.ac.ir/article-1-1206-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
159
163
article
GROWTH INHIBITION OF PATHOGENS BY LACTIC ACID BACTERIA PRODUCING INHIBITORY SUBSTANCES
FARROKH A. NAKHDJAVANI
1
NASRIN MOAZAMI
2
HASSAN LAMEA
3
From the Department of Microbiology, Medical Science Faculty, Tarbiat Modarres University, Tehran
, the Department of Biotechnology, Iranian Research Organization for Science and Technology, p.o. Box 15815-3338, Tehran
the Food Science and Technology Center, Postgraduate and Advanced Research Branch, Islamic Azad University, P.O. Box 19395-1775, Tehran, Islamic Republic of Iran.
71 samples of milk and dairy products were collected from 18 cities throughout
Iran. 93 strains of lactic acid bacteria (LAB) were isolated and assayed against four
opportunistic patho gens including E. coli, proteus and klebsiella as gram-negative
and S. aureus as a gram-positive organism. All indicators (organisms) were
hospital strains. Among isolated bacteria, lactobacilli (37 isolates) had stronger
activity against gram-negative pathogens. 37 isolates were lactococci out of which
9 strains were leuconostocs and seven strains were S.jaecalis. S. aureus was more
sensitive to lactococci than lactobacilli. Only one isolate of leuconostoc inhibited
the growth of gram-negative indicators, but five isolates inhibited S. aureus. The
use of bacteriocin-producing lactic acid bacteria in dairy products provides a
natural mean of preservation.
http://mjiri.iums.ac.ir/article-1-1205-en.pdf
Lactic Acid Bacteria
Bacteriocin
Growth Inhibition
Antibiosis.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
153
158
article
THE MORPHO-FUNCTIONAL STATE OF THE BRAIN UNDER CONDITIONS OF HYPOKINESIA AND ITS POSSIBLE PHARMACOLOGICAL CORRECTION BY GABA-ERGIC SUBSTANCES
VILEN P. HAKOPIAN
1
ALEXANDER S. KANAYAN
2
KARINE V. MELKONIAN
3
From the Department of Pharmacology, State Medical Institute, Yerevan, Republic of Armenia.
In this paper it has been shown that deterioration of the brain cortex capillary
system and negative dynamics of cerebral tissue morphology occur under conditions
of hypo kinesia. Simultaneously, gamma-aminobutyric acid (GABA) and piracetam
have been shown to favor the development of vasodilation and prevent further
worsening of the cerebral blood supply. During the experiment, it was also
established that among the substances investigated, the specific antagonist of
GABA-receptors-bicuculline-displays the strongest cerebroprotective effect in
early hypokinesia.
http://mjiri.iums.ac.ir/article-1-1204-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
149
152
article
PHARMACOLOGICAL EVALUATI ON OF MEDICINAL PLANTS FOR THEIR ANALGESIC ACTIVITY IN MICE
FAYYAZ AHMAD
1
RAFEEQ ALAM KHAN
2
SHAHID RASHID
3
From the Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
The selected parts of four medicinal plants, Achillea millefolium, Hibiscus
rosasinensis, Linum usitatissimum and Pluchea lanceolata were extracted in
absolute methanol to determine their analgesic activity. Analgesic activity was
assessed on intact mice by tail flick latency via the tail immersion method. The
analgesic activities of these plant extracts were compared with acetylsalicylic acid
(300 mg/kg) which was used as the standard drug. Extracts were given orally in
doses of 300,500 and 1000 mg/kg. 0.9% saline was administered to the control
group of animals. Results showed that Linum usitatissimum and Pluchea lanceolata
possessed highly significant analgesic activity, while Achillea millefolium and
Hibiscus rosasinensis did not show any significant effects.
http://mjiri.iums.ac.ir/article-1-1203-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
145
148
article
BACTERIAL CONJUNCTIVITIS IN ZAHEDAN
HA SHAHRIARI
1
KA GHAVIMI
2
MI QURESHI
3
From the Zahedan University of Medical Sciences, P.O. Box 98132-396, Zahedan, Islamic Republic of Iran.
The objective of this study was to determine the most common type of pathogen
causing conjunctivitis. Out of 495 patients who referred to the Zahedan Eye Clinic
from May 22, 199 1 to October 22, 1992,296 cases were diagnosed as nonbacterial
conjunctivitis. From the remaining number of cases, two patients had chlamydia and
six patients had Candida albicans, while the frequency of bacterial infection was as
follows: N. gonorrhoeae7 patients, Hemophilus aegyptius in 11 patients, M oraxella
lacunata in 6 patients, Streptococcus pneumoniae in 57 patients, E. coli in 5 patients,
Staphylococcus aureus in 5 patients, Proteus mirabilis in 5 patients, Pseudomonas
aeruginosa in 8 patients, Gardnerella vaginalis in 4 patients, and providencia
species in one patient. Bacterial agents were isolated by Gram staining and culturing.
In conclusion our results show that the most common cause of conjunctivitis is
nonbacterial, but the most common cause of bacterial conjunctivitis is S. pneumoniae.
Furthermore, our incidence of chlamydia and N. gonorrhoeae was also more than
that in the literature.
http://mjiri.iums.ac.ir/article-1-1202-en.pdf
Bacterial conjunctivitis
conjunctivitis
ophthalmia neonatorum.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
137
143
article
MUSCARINIC RECEPTOR SUBTYPES IN SMOOTH MUSCLE FROM THE BODY OF HUMAN STOMACH
SLOBODAN M JANKOVIC
1
DUSAN B. BELESLIN
2
From the Department of Pharmacology, Medical Faculty, Kragujevac, Serbia, FR Yugoslavia
Up to date, there are four pharmacologically characterized subtypes of
muscarinic receptors (M1, M2, M3 and M4). In our study we have investigated
muscarinic receptor subtypes in smooth muscle layers of human stomach. Isolated
preparations of longitudinal and circular muscle layers from human stomach were
used. Acetylcholine, bethanechol, carbachol, pilocarpine and AHR -602 produced
concentration-dependent tonic contractions of isolated preparations of both
longitudinal and circular muscle layers. Only pilocarpine increased the amplitude
of spontaneous contractions of circular muscle preparations.
Atropine, trihexyphenidyl, pirenzepine, telenzepine, hexocyclium, gallamine
and scopolamine butylbromide concentration-dependently blocked tonic
contractions of isolated preparations of both circular and longitudinal muscle
layers caused by acetylcholine. Pancuronium did not block tonic contractions
caused by acetylcholine, while para-fluoro-hexahydro-sila-difenidol (pFHHSiD)
produced weak concentration-dependent blockade of tonic contractions caused by
acetylcholine in circular muscle preparations only. The most potent antagonists
were M1 selective antagonists: trihexyphenidyl, telenzepine and hexocyclium.
These results suggested a predominance of the M1 muscarinic receptor subtype in
smooth muscle of the human stomach.
http://mjiri.iums.ac.ir/article-1-1201-en.pdf
Muscarinic receptor subtypes
stomach
body
human.
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
125
132
article
PREVALENCE, PATIENT AWARENESS AND CONTROL RATES OF HIGH BLOOD PRESSURE IN THE ADULT POPULATION OF TEHRAN: A REPORT FROM THE TEHRAN BLOOD PRESSURE S TUDY, 1990-19911
SEYED HASSAN AREFI
1
MOHAMMAD H. BASTAN HAGH
2
MORTEZA NAGHAVI
3
SEYED EBRAHIM KASSAIAN
4
SEYED SINA MARASHIE
5
FARIBORZ MORTAZAVI
6
GITA GIDASI
7
From the Cardiovascular Research Center, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
The "Tehran Blood Pressure Study" (TBPS) is an observational cross-sectional study
performed on men and women aged 15 years or more during the years 1990-1991. The study
has been designed and performed by the Tehran University of Medical Sciences'
Cardiovascular Research Center, with the primary objective of determining the prevalence
and distribution of high blood pressure in Tehrani adults. In addition, awareness levels,
control rates, and the prevalence of other cardiovascular risk factors among those with high
blood pressure, as well as associations between blood pressure (BP) levels and certain
epidemiologic and anthropometric factors have been studied. The study population comprised
10180 male and female inhabitants of Tehran aged above 15, selected by random sampling
in 50 districts of the city.
The mean and the 95% confidence interval for systolic blood pressure (SBP) and
diastolic blood pressure (DBP) were 123 (122.8-123.4) and 75.4 (75.2-75.6), respectively.
The prevalence of high blood pressure (SBP≥ 140 mmHg or DBP> 90 mmHg or drug
consumption) was 17.6% in males, 17.9% in females, and 17.7% in generaL
About 47% of the patients with high DBP readings were aware of their condition. In
20% of these, control of hypertension had been achieved by drug therapy in 11 %, drug
therapy had failed to control hypertension, and 16% were not receiving treatment despite
their awareness. High body mass index and a history of diabetes were more frequent in those
with high BP readings than the general population. Of those with high BP readings, most
had only mild elevations of BP (90≤ DBP≤99 or 140≤SBP≤159). Isolated high systolic
blood pressure (SBP ≥140 mm Hg and DBP< 90 mmHg) was found in 36% of females and
30% of males aged above 64.
The noticeable prevalence of high BP, the remarkable prevalence of isolated high
systolic blood pressure in the elderly, the very low level of patient awareness and low control
rates all necessitate the adoption of appropriate personal and community health policies.
http://mjiri.iums.ac.ir/article-1-1200-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
117
124
article
THE EFFECTS OF DEPRESSION ON ENDOICRINE AND IMMUNE SYSTEMS
MH GHAHRAMANI
1
M NAZARI
2
SZ TABEI
3
J AHMADI
4
SN RAFATI
5
MA GHALAMBOR
6
From the Schools of Paramedical Sciences , Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
From the Schools of Paramedical Sciences , Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
From the Schools of Medicine, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
From the Schools of Medicine, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
From the Schools of Paramedical Sciences , Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
To study the effect of depression on the endocrine and immune systems, 557
male freshman and sophomore medical students (20-30 years old) were given
Beck's Depression Inventory. Students with marks 5 or above were selected as the
control (n=26) and those with marks of 20 or higher were chosen as the test group
(n=27). All of the students were subjected to the following tests: CBC, differential,
total cholesterol (TC), triglycerides (TG), HDL-c, VLDL-c, fibrinogen (Fibr),
cortisol (Cort), prolactin (PRL), testosterone(Test), triiodothyronine (T3), thyroxine
(T4), total serum immunoglobulins (Ig), IgA, IgG, IgM, creatine kinase (CK),
and C3 and C4 components of the complement system.
Results indicated statistically significant increases of the following parameters
in the test group as compared with the controls: TC (P < 0.05), LDL-c (P <
0.05), CK (P < 0.025), Fibr (P < 0.0 1), Test (P < 0.05), Cort (P < 0.025), IgG (P
< 0.025) and Ig (P < 0.025). The results were in accordance with the anticipated
hormonal and cell-mediated immunity alterations caused by depression, which
affected both cytokines and endorphin levels.
In spite of the limited number of subjects used in this study and lack of the
dexamethasone suppression test (DST), the overall approach of this study is
encouraging nevertheless, further studies using a 1zrger sample are required.
http://mjiri.iums.ac.ir/article-1-1199-en.pdf
Depression
behavioral diseases
affectional abnormalities and schizophrenia
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
113
115
article
A NEW MODIFIED SURGICAL APPROACH IN LYMPHEDEMA OF THE PENIS AND SCROTUM
H HODJATI
1
AA KHEZRI
2
From the Department of Surgery, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
A 14 year old boy suffering from marked penoscrotal lymphedema is
reported. Reduction scrotoplasty was done and the neoscrotum was made by
combining the anterior suprapubic and posterior scrotal V-shaped flaps. A split-thickness
skin graft from the thigh was placed over the denuded penis. No
complication was encountered and the cosmetic result was satisfactory
http://mjiri.iums.ac.ir/article-1-1198-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1996-08
10
2
99
111
article
PERFORATION OF THE ESOPHAGUS A 12-YEAR EXPERIENCE
V MONTAZERIE
1
From the Department of Thoracic Surgery, Imam Khomeini Hospital, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of. lran.
Esophageal perforation continues to be a difficult diagnostic and management
problem. Recommendations regarding treatment remain controversial. 17 patients
with perforation of the esophagus were retrospectively reviewed at the Thoracic
Surgery Unit of Imam Khomeini Hospital between 1981 and 1992. The majority
of the injuries involved the thoracic esophagus (10 or 59%), followed by the
cervical (6 or 35%), and the intra-abdominal esophagus (1 or 6%). Perforations
caused by external trauma constituted most of the injuries (47%), followed by
ingested foreign bodies (29%), iatrogenic causes (18%), and spontaneous perforation
(6%). Excluded from this study were patients with tracheoesophageal
fistulas, postoperative esophageal anastomotic leaks, and perforations due to
esophageal carcinoma. Esophageal radiographic contrast studies with either
Gastrografin or barium were performed in 11 patients with 2 (18%) false-negative
results. Fever, chest pain, dysphagia, dyspnea and crepitus were common clinical
findings. 2 patients (12%) were treated conservatively, 3 (18%) by primary repair
and drainage, and 12 (70%) by drainage and diversion with or without exclusion.
The author puts great emphasis on mediastinal drainage and irrigation in addition
to diversion in late diagnosed cervical or thoracic esophageal perforations with
pleural and mediastinal contamination.
http://mjiri.iums.ac.ir/article-1-1197-en.pdf