eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
317
319
article
A CASE REPORT OF MADUROMYCOSIS (PSEUDALLESCHERIA BOYDII) INFECTION TREATED WITH KETOCONAZOLE
M MOGHADDAMI
1
M VALIKHANI
2
From the Department of Medical Mycology, School of Public Health and Institute of Public Health Research and Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
A case of mycetoma of the arm caused by Pseudallescheria boydii in a 56-
year-old woman is described. Response to oral administration of ketoconazole
was successful.
http://mjiri.iums.ac.ir/article-1-1242-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
313
316
article
REPORT OF FOUR CASES OF FAMILIAL IDIOPATHIC PULMONARY FIBROSIS
PARVIZ VABEDI
1
From the Mashad University of Medical Sciences, Mashad, Islamic Republic of Iran.
A 25 year old male and his 46 year old aunt presented with shortness of
breath and a dramatic response to steroids. The other two patients are sisters
with more advanced disease. One of these responded partially to steroids,
while the other died within 4 months of treatment. The genetic basis and
pathogenesis are discussed.
http://mjiri.iums.ac.ir/article-1-1241-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
305
311
article
PENDRED\'S SYNDROME REVISITED
M DJALILIAN
1
M FARHADI
2
F NAZEM
3
From the Department of Otorhinolaryngology, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Pendred's syndrome is defined as a triad of congenital perceptive
hearing loss, goiter, and abnormal perchlorate test.
Three brothers with Pendred's syndrome [P.S.] are reported. The
oldest brother has hearing loss (he has been deaf and mute since childhood)
and has a large goiter. A thyroid scan revealed euthyroid multinodular goiter
and a perchlorate test was performed, and reported abnormal.
His brother had the same manifestations but with less severity and after
subtotal thyroidectomy, the pathology report revealed follicular carcinoma.
The youngest brother had hearing loss since childhood but a normal
sized thyroid. We report three patients and compare the frequency of their
symptoms with that reported in the literature.
http://mjiri.iums.ac.ir/article-1-1240-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
297
304
article
EFFECTS OF DIFFERENT MEDIATORS ON FIBROBLAST PROLIFERATION
AME NOURI
1
IM LEIGH
2
J MANGERA
3
A SHAMSA
4
H FESTENSTEIN
5
From the Department of Immunology and Experimental Dermatology, The London Hopital, London EI 2A D
the 'Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran
In this study, we have investigated the proliferative response of human
dermal fibroblasts isolated from normal and psoriatic individuals to different
cytokines. We found that IL-1, TNF (α) and EGF are stimulatory whereas
IFN « and 1 both showed inhibitory activity on fibroblast proliferation.
IL-6 a more recently described cytokine, showed no detectable effects on cell
proliferation. Investigating the combined effects of these mediators on
fibroblasts, we found that while EG F has additive effects on IL-1 orTNF (α)
activated cells, both IFNs showed suppressive activity on the cell proliferation.
There was no statistical difference in proliferative response of fibroblasts
isolated from normal and psoriatic individuals. The significance of these
findings is discussed,
http://mjiri.iums.ac.ir/article-1-1239-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
293
296
article
PRODUCTION AND CHARACTERIZATION OF HUMORAL IMMUNE RESPONSE AGAINST MUSTARD GAS
R REZAEIPOOR
1
G BUNGIE POOR
2
From the Immunology Department, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
One of the promising aspects of the immunological research on
chemical war gas is to investigate the immunogenicity of some hazardous
compounds such as mustard gas.
Mustard gas is categorized as a "hapten" based on its physical and
chemical properties. Haptenic chemicals which do not possess immunogenicity
could be immunogenic experimentally when conjugated with
a suitable protein carrier. To do so, mustard gas was coupled to a protein
carrier and injected to an animal model (rabbit). After hyperimmunization,
specific antibodies were obtained through special purification procedures
and used in different immunological tests. It was observed that there are two
different groups of antibody populations, one against the haptenic group and
the other towards the protein carrier.
http://mjiri.iums.ac.ir/article-1-1238-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
287
292
article
EFFECTS OF CATECHOLAMINES ON DOPAMINE AND SEROTONIN SYNTHESIS IN RAT BRAIN STRIATAL SYNAPTOSOMES: THE ROLE OF PRESYNAPTIC RECEPTORS AND THE SYNAPTOSOMAL REUPTAKE MECHANISM.
M MESSRIPOUR
1
JB CLARK
2
From the Biochemistry Department, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran
the Biochemistry Department, St. Bartholomew's Hospital Medical College, University of London, London ECIM 6B2.
The regulation of dopamine and serotonin synthesis in rat brain striatal
synaptosomes has been studied using HPLC methods. Noradrenaline was
shown to markedly inhibit both the synthesis of dopamine and serotonin.
The response of the synaptosomes to the concentrations of noradrenaline
appeared to be biphasic, a very effective inhibition occurring at low
concentrations (1-5 µm) and a relatively ineffective further inhibition
occurring at high concentrations (up to 100 µM). The inhibition of dopamine
and serotonin synthesis by noradrenaline was also studied in the presence of
phenoxybenzamine (alpha adrenergic receptor blocker) and imipramine
(reuptake inhibitor). Phenoxybenzamine changed the pattern of inhibition
of both dopamine and serotonin synthesis by noradrenaline by preventing
the very effective inhibition previously seen at low (1-5 µM) noradrenaline
concentrations. Imipramine, whilst showing marked inhibition of dopamine
synthesis on its own, prevented any inhibition by noradrenaline. In the case
of serotonin synthesis, however, imipramine alleviated some of the inhibition
seen in the presence of noradrenaline alone. The results are discussed
with respect to the role that presynaptic receptors and reuptake mechanisms
play in the regulation of catecholamine and serotonin synthesis at the nerve
ending.
http://mjiri.iums.ac.ir/article-1-1237-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
283
285
article
A DECREASE IN THE INCIDENCE OF SYPHILIS IN IRAN AND THE EFFECT OF ISLAMIC RULES IN CONTROLLING SEXUALLY TRANSMITTED DISEASES
NASSER SIMFOROOSH
1
From the Department of Urology, Shahid Beheshti University of Medical Sciences. and the Iranian Blood Transfusion Center. Tehran, Islamic Republic of Iran
Venereal diseases are still a common problem in today's world. Even
though tremendous advances are being made in medicine and large budgets
are being spent to control sexually transmitted diseases (STD), especially in
western countries, these diseases are still yet very common, and today AIDS
has been added to the threats posed by STD to human life. The status of
syphilis was evaluated in Iran in the years before and after the Islamic
Revolution by comparing RPR test results in blood specimens obtained for
transfusions from all groups of the society. RPR positivity was 0.6% for the
years 1974-76, while it was only 0.2% for the years 1985-87, demonstrating a
sharp decline. Divine laws, especially those offered by Islamic rules, are
much more effective than present expensive medical measures to control
venereal diseases, and can return sexual health to the human society.
http://mjiri.iums.ac.ir/article-1-1236-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
279
282
article
PERFORMANCE OF IRANIAN CHILDREN ON THE DRAW-A-MAN TEST
E NADERI
1
M SEIFNARAGHI
2
From the School of Education and Psychology, Tarbiat Moallem University
the Allameh Tabatabai University, Tehran, Islamic Republic of Iran
In this study, the Draw-A-Man Test was administered to 183 Iranian
children, 96 boys and 87 girls from age of 36 to 119.5 months. The subjects
were selected randomly from middle-class families in Tehran. The results
show that younger Iranian children scored higher than the older ones. In
addition to the age differential on performance, sex differences on drawing a
man were tested by means of the T -test for each age group. The results show
that enviroment affects the children's drawings. Also, some comparisons of
the findings of this study with others confirm the cultural effects on children's
performance on the DAM test.
http://mjiri.iums.ac.ir/article-1-1235-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
275
278
article
RUBELLA IMMUNITY IN JUNIOR HIGH SCHOOL GIRLS IN URBAN AND RURAL REGIONS OF TONKABON DISTRICT, MAZANDARAN PROVINCE, ISLAMIC REPUBLIC OF IRAN
MM SEMSAR-YAZDI
1
R NATEGH
2
H MALEKAFZALI
3
P KAMALI
4
A BINIAZ
5
N SABOURI
6
T MOKHTARI-AZAD
7
P REZAI
8
OSSIA
9
From the School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, and the Ministry of Health and Medical Education, Tehran, Islamic Republic of Iran.
In this report, a seroepidemiological survey was performed to determine
the prevalence of rubella immunity and antibody titer in 11-16 year old
girls in urban and rural areas of Tonkabon district in northern Iran. The
results and conclusion are presented.
http://mjiri.iums.ac.ir/article-1-1234-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
269
174
article
PROPHYLACTIC ANTIBIOTICS IN CESAREAN SECTION: A DOUBLE BLIND AND RANDOM STUDY ON 210 IRANIAN WOMEN
H DABIRASHRAFI
1
K MOHAMAD
2
M MOHAMADI
3
N MOGHADAMI TABRIZI
4
N MOSLEMIZADEH
5
P MALEKDAR
6
From the Department of Obstetrics and Gynecology, Mirza Kouchek Khan (Zanan) Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
210 Iranian women participated in a study in two main categories
(comprising six subgroups) for comparison of prophylactic antibiotic prescription
by the intravenous route with the irrigation method together with
control subgroups. Interesting results from our study were:
1- There was no significant statistical difference between subgroups with
regard to infectious morbidity.
2- The rate of early infectious morbidity in our patients was lower than in
American studies.
3- Late infections were more common than early infections in our study.
4- The rate of late endometritis in the irrigation subgroup under category of
labor lasting less than six hours was significantly lower than the irrigation
subgroup in the category of labor lasting more than six hours.
We think that the results of a particular study investigating the
usefulness of prophylactic use of antibiotics at cesarean section from one
country is not necessarily relevant for another country having a different
culture and customs.
http://mjiri.iums.ac.ir/article-1-1233-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
265
267
article
A SURVEY OF 200 DCR OPERATIONS
H RAZMJOO
1
From the Department of Ophthalmology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.
In a prospective survey, 200 cases of operated chronic dacryocystitis
were divided into three groups according to the kind of operation, and the
respective results are as follows:
Group I includes 100 cases in whom the lacrimal bone was removed
(8mm x 8mm) and a 6mm diameter catheter was used (as a duct between the
lacrimal sac and nasal cavity). The recurrence rate within one year was 24 % .
Group II consists of 50 patients in whom a hole about 17mm x 17mm
was made (in the lacrimal sac area at the orbit), an 8mm diameter catheter
was installed and anterior mucosal flaps were repaired. This technique led to
95% recovery.
Group III consists of 50 cases who underwent the same technique as
group II without using the catheter and by repairing both anterior and
posterior mucosal flaps. The result was 98% successful. In conclusion, the
following are suggested as the major factors determining successfulness of
DCR operations.
1. Removing the bone around the lacrimal sac about 17 x 17mm,
2. Releasing the lacrimal sac from the adjacent bone,
3. Making an incision at the third inferior part of the lacrimal sac,
4. Identifying the lacrimal sac exactly, and
5. Making free direct communication between the nasal cavity and the
lacrimal sac.
http://mjiri.iums.ac.ir/article-1-1232-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
263
264
article
F.A.B.CLASSIFICATION OF CHILDHOOD LEUKEMIA IN IRAN
AA POURFATHOLLAH
1
M RAKHSHAN
2
M AHMADI
3
M IZADYAR
4
From the Tarbiat Modarres University', Department of Pathology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences
and the Departments of Pathology and Hematology, Children's Medical Center. Tehran University of Medical Sciences
Bone marrow specimens from leukemic patients were studied in a 5 year
period beginning in 1982 in Children's Medical Center of Teheran,a teaching
and referral center for pediatric medicine. The slides were stained by
Giemsa-Wright stains, read by at least two persons experienced in bone
marrow pathology and classified according to F.A.B. recommendations.
Peroxidase or Sudan black-B and P.A.S. reaction were used fordifferentiation
of myeloblasts from lymphoblasts when required. Acute lymphoblastic
leukemia is the most prevalent childhood leukemia in Iran, as it is in other
countries, but the incidence is relatively lower compared to western
countries. The percentage of all leukemic subtypes are almost similar to
other reports except for L2, Ml and M2 where L2 has a relatively lower
occurrence with Ml and M2 being more prevalent.
http://mjiri.iums.ac.ir/article-1-1231-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
259
261
article
IMMUNOLOGICAL PHENOTYPING OF ACUTE LYMPHOBLASTIC LEUKEMIA ( ALL) IN UNIVERSITY AFFILIATED HOSPITALS: A PRELIMINARY REPORTON 50 PATIENTS
SZ TABEI
1
Z AMIRGHOFRAN
2
From the Department of Pathology, Shiraz University of Medical Sciences, School of Medicine, Shiraz, Islamic Republic of Iran'
the Tarbiat Modarres University
The peripheral blood and bone marrow samples from 50 patients with
ALL were investigated by indirect immunofluorescent technique. The most
common type of ALL was common-ALL (82%) and the least common was
T-ALL (2%). Other subtypes of ALL were unclassified by our technique
(8%), B-ALL (4%), and pre B-ALL (4%). The correlation between
immunophenotype, clinical condition and hematological profile is discussed.
http://mjiri.iums.ac.ir/article-1-1230-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
255
258
article
BIRTH AND DEATH INDICATORS IN THE ISLAMIC REPUBLIC OF IRAN IN 1984 AND 1986
H MALEK-AFZALI
1
From the Council for Expansion of Education and Research, Ministry of Health and Medical Education, Tehran, Islamic Republic of Iran.
Birth and death indicators were examined through retrospective
surveys conducted in 1985 and 1987 in the Islamic Republic of lran, reviewing
1984 and 1986 events, to obtain infant mortality rate (IMR) and other
necessary indicators for health planning and evaluation.
Comparison between 1985 and 1987 surveys revealed:
1. No major change in crude death rate ( 6.3 per 1000 in 1987 survey) had
occurred.
2.IMR was 51 per 1000 live births in 1987 survey.
3. The proportion of death rate in children under 5 year to total death has
dropped in rural areas from 55 per 100 to 48, and in towns froms 32 to 29.
4. Still about 20 and 22 per 100 deaths in urban and rural areas respectively in
under 5 children are due to diarrhea the percentage of those due to infectious
diseases in the same areas and age group, is 30 and 32 per 100.
5. Birth rate has dropped from 40.4 to 37.7 per 1000 as a result, natural
growth of population has decreased from 3.40 per 100 in the 1985 survey to
3.14 in 1987.
6. Maternal mortality rate has dropped considerably in rural areas, from 23
per 10,000 live births to 18.
http://mjiri.iums.ac.ir/article-1-1229-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-02
2
4
249
254
article
A NEW APPROACH TO VESICOURETERAL REFLUX PERSISTING AFTER POSTERIOR URETHRAL VALVE ABLATION USING GIL-VERNET ANTIREFLUX TECHNIQUE
NASSER SIMFOROOSH
1
From the Department of Urology, Shahid Labbafi Nejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
Classic anti reflux procedures on children with a history of posterior
urethral valve does not usually yield good results and often ends up with
ureteral obstruction and even permanent urinary diversion.
From 1981 through 1988,21 boys with history of posterior urethral valve
(PUV) underwent evaluation for vesicoureteral (VU) reflux 17 boys had
VU reflux. Following valve ablation, reflux disappeared in nine cases. Eight
boys continued to have reflux (average follow up after valve ablation was 17
months). The grade of refluxes was IV or higher in all of the cases. Gil-Vernet
anti reflux procedure was performed in these boys. VU reflux disappeared in
11 of 12 refluxing ureters in these eight boys postoperatively. An excellent
success rate (91.7% ) was seen without upper tract deterioration in any of the
cases. Average follow up was six months with the longest being 13 months.
This is the first report of the application of Gil-Vernet antireflux technique
in persistent reflux following valve ablation and seems a breakthrough in
managment of PUV refluxes, eliminating the need for preliminary diversion
as performed in the past.
We recommend this simple, highly effective approach as the procedure
of choice in managment of VU refluxes following valve ablation in children
with PUV.
http://mjiri.iums.ac.ir/article-1-1228-en.pdf