eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
169
173
article
NEUTROPHIL CHEMOTACTIC DEFECT IN 60 PATIENTS WITH RICKETS
A FARHOUDI
1
MORADINEJAD
2
T SEPEHRZAD
3
From the Immunology and Allergy Dept., Children s Medical Center, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Neutrophil mobility in 60 patients with vitamin D-deficient rickets is
studied, and the patients are followed after therapy by 600,000 units vitamin
D. 28 of 60 patients (46%), had low chemotaxis for neutrophils before
vitamin D injection (migration), and 36 of 60 (60%) had low random
mobility. The results showed a significant improvement after vitamin D
therapy furthermore, the level of calcium and phosphorus reached normal
levels after treatment of the patients as well. We have previously studied
neutrophil mobility in 10 patients with rickets2 This report serves to
complement our previous preliminary report.
http://mjiri.iums.ac.ir/article-1-1585-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
165
168
article
EFFECT OF GLUCOSINOLATE AUTOLYSIS PRODUCTS ON RAT SERUMT3 AND T4 CONCENTRATIONS
SULEIMAN AFSHARYPOUR
1
ALI HAERY
2
From the Faculty of Pharmacy, and the School of Medicine, Department of Pharmacology, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.
The glucosinolate autolysis products of crushed seeds of DesclIrainia
sophia L. (khakeshi) and Brassica napus L. (shelghem) were administered
orally to rats in doses representing 8,16 and 32 gm seeds/kg body weight/day
at intervals of 10, 20 and sometimes 30 days. Serum T3 and T4 concentrations
were reduced in 10 day•autolysate treated animals in a similar fashion to that
found with methimazole. The antithyroid effect persisted until day 20, but
was weaker than that seen with methimazole. By day 30, serum T3 and T4
concentrations returned to normal in plant treated animals.
http://mjiri.iums.ac.ir/article-1-1584-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
157
164
article
PURIFICATION AND PROPERTIES OF RAT GASTROCNEMIUS MUSCLE N-ACETYL-I3-DGLUCOSAMINIDASE A AND B.
JA KHAN
1
MHR LEWIS
2
From the Department of Biochemistry, Medical Biology Center, Queen s University of Belfast, BT97BL, Northern Ireland, United Kingdom
N-acetyl-B-D-Glucosaminidase was purified by affinity and ionexchange
chromatography. Two major, A and B, and three minor intermediate
forms were isolated and characterized. NAG-A and NAG-B
were purified 440 and 1200 fold with final yields of 16 and 23 percent
respectively. Each activity was represented by a single protein band. After 70
min preincubation at 55°C a loss of70% activity of NAG-A and 30% activity
of NAG-B respectively was observed. Divalent metal ions had no significant
effect on either enzyme activity. N-acetyl-D-glucosamine was determined to
be a competitive inhibitor for both activities. The method of purification
reported here will be of significance in providing larger quantities for the
better understanding of both Tay-Sach's and Sandhoff's diseases.
http://mjiri.iums.ac.ir/article-1-1583-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
151
155
article
ESTIMATION OF POTASSIUM, CALCIUM, AND MAGNESIUM IN BLOOD AND MYOCARDIAL TISSUE, AND DIAGNOSTIC IMPORTANCE OF URINARY MAGNESIUM EXCRETION IN EXPERIMENTALLY-INDUCED MYOCARDIAL INJURY
KASHAV ANAND
1
ABRAR ALI KHAN
2
RAJENDRA KUMAR GUPTA
3
From the Department of Physiology, Department of Anatomy, and Department of Pathology, School of Medicine, Kerman University of Medical Sciences, Kerman, Islamic Republic of Iran.
The results obtained in the present investigations point to a definite
correlation between the onset of myocardial injury, electrocardiographic
changes and biochemical changes. Changes in the electrocardiogram and
elevated serum levels were paralleled by an increased excretion of magnesium
in urine as early as one hour. Serum calcium and serum potassium levels
did not show any significant result, but in coming days these ions including
serum magnesium might help clinicians diagnose myocardial infarction. In
this study, increased urinary magnesium excretion was found to coincide
with elevated serum transaminases, and it is suggested that in addition to the
other establised diagnostic criteria, estimation of serum as well as urinary
magnesium may be used as an additional index of myocardial infarction.
http://mjiri.iums.ac.ir/article-1-1582-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
143
149
article
A STUDY OF ONYCHOMYCOSIS IN TEHRAN
MAHIN MOGHADDAMI
1
MOHAMMAD REZA SHIDFAR
2
From the Dept. of Medical Micology, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
The main purpose of this original investigation is to report the results of
the study on the frequency and type of the fungi that cause onychomycosis in
Tehran.
In a mycological study of patients with onychopathy during a period of
18 months, mycotic infection of the nail plate in 268cases outof927 examined
persons were noticed. The causative agents were candida (66.04%), dermatophytes
(32.1 %), and mold (1.86%).
Candida onychomycosis was more common in women than men. The
most frequently occurring species was C. albicans (66.6%). T. unguium was
predominant in the males and T. rubrwl1 was the most frequently isolated
fungus being present in 50% isolates. Nondermatophytic onychomycosis
was seen in toe nails in all cases. The etiologic agents were Aspergillus 4 and
penicillium species 1
http://mjiri.iums.ac.ir/article-1-1581-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
139
141
article
LAP AROSCOPIC OVARIAN ELECTROCAUTERIZATION (LEC)
HORMOZ DABIRASHRAFI
1
YAHYA BEHJATNIA
2
KAZEM MOHAMAD
3
NASRIN MOGHADAMI-TABRIZI
4
Seventeen patients with polycystic ovarian disease (peOD) were
treated by laparoscopic ovarian electrocauterization (LEC). Ten were
admitted to hospital for infertility, four for hirsutism, two for severe scalp
hair loss, and one for abnormal uterine bleeding. Four of the patients were
virgins. We had 50% (5 of 10) pregnancies and 88% (15 of 17) showing a
decline in testosterone levels after this operation. 87% of the patients
showed regularity in menstruation. 80% (8 of 10) of infertile patients
ovulated after LEe. We think the use of LEe for the treatment of severe
scalp hair loss and in virginal peo patients are new ideas in our article. The
rate of pelvic adhesion after LEe was 0% in our series. A 6-to-24 month
follow-up showed that many of these patients had normal clinical and
laboratory findings.
http://mjiri.iums.ac.ir/article-1-1580-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
129
138
article
NEOPLASTIC CAUSES OF SPINAL CORD AND CAUDA EQUINA COMPRESSION IN ADULTS: PATHOLOGICAL AND STATISTICAL FEATURES
MOHAMMAD R. ARDEHALI
1
From the Department of Neurological Surgery, Nemazee Hospital, Shiraz University of Medical Sciences. Shiraz. Islamic Republic of lran.
This presentation analyses the histological types, relative incidences,
age, sex and anatomical distributions of one hundred and seventy-nine
biopsy proven tumors of the spinal canal from a general hospital in Iran.
Particular attention is paid to differences in the relative incidence of these
tumors compared with that in various published reports and the statistics
from several eastern countries are compared with those from the West.
In the patients studied, secondary tumors were the most frequent causes
of spinal cord and cauda equina compression (39.6%), followed by nerve
sheath cell tumors (24.5%), meningiomas (20%) and neuroepithelial tumors
(10%). Among the secondary tumors, the most common metastatic tumor
was the lymphoma and the most common vertebral column neoplasm was the
myeloma, each accounting for 8.9% of the entire series, an unusually high
proportion for the myeloma.
http://mjiri.iums.ac.ir/article-1-1579-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
125
128
article
PROGRESSIVE NEUROLOGICAL DEFICIT DUE TO NEGLECTED DURAL REPAIR IN WAR CASUALTIES
MAZIAR AZAR
1
From the Department of Neurosurgery, Amiralmomenin Hospiral, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
One hundred patients underwent elective cranioplasty for high velocity
missile injury of the head during a 30-month-period study and investigation
in Amiralmomenin Hospital affiliated to Iran University of Medical Sciences.
Deep penetrating wounds were the most frequent injuries seen during
this study. Three patients presented with massive bone defects and progressive
neurological deficit and during the operation it was noted that dural
repair had not been done. It was suggested that intermittent brain herniation
was the probable cause of progressive brain damage.
http://mjiri.iums.ac.ir/article-1-1578-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
119
124
article
SACROCOCCYGEAL TERATOMA
MH KHERADPIR
1
K MUELLER
2
From the Department of Pediatric Surgery, Children s Hospital Medical Center, University Clinic of Tehran and Zurich, Iran/ Switzerland.
31 cases of sacrococcygeal teratoma from the Children's Hospital of
Ziirich and 25 cases from the Children's Hospital of Tehran are evaluated
and compared. In seven cases the tumors were organized. They contained
parts of organs or rudimentary extremities. According to general experience
the malignancy of tumors is higher in children who are operated on after their
second to fourth month of life (35% versus4.5% in Ziirich, 37% versus 0% in
Tehran).
Our experience emphasizes the importance of an early extirpation of
sacrococcygeal teratoma, even in cases with a relatively small looking
external tumor. Because of the risk of a tumor recidive the coccyx should be
removed in all cases.
http://mjiri.iums.ac.ir/article-1-1577-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
113
117
article
VITRECTOMY IN CHRONIC UVEITIS
HAMID AHMADIEH
1
HAMID SAJJADI
2
MOHSEN AZARMINA
3
HOOSHANG FAGHIHI
4
From the Department of Ophthalmology, Labbafinejad Mwdical Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Vitrectomy was performed on 25 eyes in 21 patients with chronic uveitis
from various etiologies. Postoperative follow up averaged 22.8 months with
visual improvement in 24 of 25 eyes.
In this retrospective study, the techniques employed and the beneficial
effect of vitrectomy alone or vitrectomy combined with cataract surgery
(Iensectomy in most cases) on improving vision and decreasing the number
and severity of recurrent attacks of uveitis are reviewed. Also, the indications
of surgery, the effect of the surgical procedure on intraocular pressure,
the prognostic factors and the management of complications are discussed.
http://mjiri.iums.ac.ir/article-1-1576-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
109
112
article
ARTILLERY SHELL FRAGMENTS IN THE HEART: DIAGNOSIS AND MANAGEMENT
MA SADR-AMELI
1
M MOHAJERI
2
A MOHEBI
3
From Shahid Rajai Heart Hospital, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Delayed evaluation and management of penetrating cardiac injuries
especially mortar fragments were performed in 30 war victims in the Shahid
Rajai Heart Hospital, Tehran. All were men with a mean age of 20.7 years.
Pleuritic chest pain was the most common symptom (53.3%), while physical
examination was negative in the majority of cases (66.8%). 50 percent of the
cases had pericardial effusion on the echocardiogram. The right ventricle
was the most frequent site of involvement (26.6%) followed by the left
ventricle (16.6% ), right atrium, left atrium, aorta (each 13.3%), pulmonary
trunk (10%), and inferior surface of the heart (6.6%). More than half of the
cases had associated hemothorax. Shell fragments were removed in all cases
but two. Fragments larger than one centimeter in the vicinity of the heart
structures in the pericardium are recommended to be removed.
http://mjiri.iums.ac.ir/article-1-1575-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-11
3
3
105
107
article
SERUM CONCENTRATIONS OF VARIOUS HORMONES FOLLOWING EXPOSURE TO CHEMICAL WEAPONS CONTAINING SULFUR MUSTARD
F AZIZI
1
H ELYASI
2
H SOHRABPOUR
3
N JALALI
4
M NAFARABADI
5
From the Endocrine Research Center and the Department of Medicine, Shahid Beheshti University Of Medical Sciences, Tehran, Islamic Republic of Iran.
Serum concentration of FSH, LH, testosterone, prolactin, ACTH,
cortisol, TSH, T4, T3 and resin T3 uptake were measured in 146 men who
were exposed to vesicants used by the Iraqi regime a few days t04 weeks prior
to testing. Clinical and laboratory findings had confirmed the use of mustard
gas.
Mean serum concentrations of FSH, LH, TSH and prolactin were not
significantly different from normal values. Free T4 index (FT41) was
subnormal in 6 men, and its mean was somewhat decreased (7.4 ± 0.8 vs
normal 8.7 ± 1.2 P < 0.05). Free T3 index (FT31) was subnormal in 14 men,
and its mean was significantly lower than normal (92 ± 20 vs 130 ± 11 P <
0.001).
Serum testosterone concentration was subnormal in 42 men, and its
mean was significantly lower than normal (361 ± 254 vs 676 ± 273 ngldl P <
0.001). Serum cortisol was subnormal in 11 and above normal in 8 men, its
mean was not significantly different from normal values. There was an
increase in serum ACTH concentration.
We conclude that exposure to chemical weapons containing mustards
may cause severe alterations in serum concentrations of various hormones.
http://mjiri.iums.ac.ir/article-1-1574-en.pdf