eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
97
101
article
INTRAMURAL TRACHEOBRONCHIAL REMNANTS: A MISDIAGNOSED CAUSE OF CONGENITAL ESOPHAGEAL STENOSIS
R.K GUPTA
1
M.H DAIE PARIZI
2
H TABRIZCHEE
3
From the Department of Pathology Kerman University of Medical Sciences, Kerman, Islamic Republic of Iran.
From Pediatrics, Kerman University of Medical Sciences, Kerman, Islamic Republic of Iran.
From the Department of Pathology Kerman University of Medical Sciences, Kerman, Islamic Republic of Iran.
In cases of congenital esophageal stenosis due to tracheobronchial
remnants, symptoms of partial esophageal obstruction appear at the time of
weaning or during early childhood. In the absence of esophagitis, esophagram
combined with cinefluoroscopy demonstrates fixed stenosis of distal
esophagus and appears to be diagnostic. Dilatation of rigid stenosis is
invariably unrewarding and surgical resection is mandatory. Pathologically,
the presence of cartilage or respiratory seromucinous glands in the
esophageal wall are pathognomonic features. Other congenital anomalies
may be encountered in some cases (30%).
http://mjiri.iums.ac.ir/article-1-1610-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
91
96
article
MITRAL STENOSIS COMPLICATED BY RENAL ARTERY EMBOLISM
M ZAMIRIAN
1
A.M HANDJANI
2
N GHAHRAMANI
3
From the Department of Medicine, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
Six patients with mitral stenosis complicated by renal artery
embolism studied prospectively are presented. In five patients there was
unilateral and in one patient bilateral renal artery involvement. The
diagnosis was confirmed by intravenous pyelography, retrograde
pyelography, renal angiography, renal scan or a combination of these. All
had atrial fibrillation, proteinuria and elevated LDH levels. Two had
developed hypertension at the initial presentation. All patients were
treated with anticoagulants and other supportive measures. One developed
reversible acute renal failure and the others had an uneventful
hospital course. Subsequent IV.P. and scans revealed nonfunctioning
shrunken kidney in just one patient with complete obstruction of the main
renal artery. We conclude that anticoagulation is an adequate substitute to
embolectomy. The main role of surgery is in occasional patients who
remain anuric despite medical therapy and in those whose angiography
reveals complete occlusion of the main renal artcry.
http://mjiri.iums.ac.ir/article-1-1609-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
87
89
article
RIGHT ATRIAL MYXOMA
A.R NIKYAR
1
From the Shahid Chamran Heart Hospital, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.
A case of right atrial myxoma in a 5 year old male is presented. The
Patient was admitted in the pediatric department with systemic manifestations.
Myxoma was incidentally diagnosed.
http://mjiri.iums.ac.ir/article-1-1608-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
83
86
article
RECONSIDERATION OF THE CAT EYE SYNDROME: RECIPROCAL TRANSLOCATION T(1l,22) LEADING TO PARTIAL TRISOMY OF llq AND 22.
R KARIMI-NEJAD
1
M GHOFRANI,
2
A NAJAFI
3
M.H KARIMI-NEJAD
4
From the Department of Pathology and Genetics, Iran University of Medical Sciences
the •• Departments of Pediatrics and Opthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
From the Departments of Pediatrics and Opthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
From the Department of Pathology and Genetics, Iran University of Medical Sciences,Tehran, Islamic Republic of Iran.
We are reporting a case of 47 chromosome complement with an extra
rearranged chromosome 22pter→22qll:: llq23 → llqter in a child with
multiple malformations whose mother has a balanced reciprocal translocation
t(1l,22) with a history of two previous abortions. We emphasize the
importance of family study in such cases.
http://mjiri.iums.ac.ir/article-1-1607-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
79
81
article
RHABDOMYOSARCOMA OF THE MIDDLE EAR IN AN ADULT
D SAVIC
1
D DJERIC
2
G STOJCIC
3
From the Clinic of Otorhinolaryngology, University Clinical Center, Pasterova 2, Belgrade 11000, Yugoslavia.
The authors present a case of embryonal rhabdomyosarcoma of the
middle ear in an adult patient. Computerized tomography indicated a
malignant tumor and the diagnosis was confirmed by pathological analysis.
http://mjiri.iums.ac.ir/article-1-1605-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
75
78
article
INHIBITION OF HUMAN ERYTHROCYTE GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY BY DEHYDROEPIANDROSTERONE AND RELATED STEROIDS.
B HAGHIGHI
1
M ANI
2
S ZAKERI
3
From the Department of Biochemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Islamic Reupublic of Iran.
The inhibitory effects of several steroids on G6PD activity using intact
erythrocytes are reported. Incubation of whole blood with dehydroepiandrosterone
(DHEA) resulted in 42% and 12% inhibition in the enzyme
activity in the presence and absence of oxygen, respectively. Addition of
epinephrine and/or aminophylline into the incubation medium caused
further enzyme inhibition suggesting a possible involvement of cAMP in the
mechanism by which G6PD activity is inhibited in the system used. The
activity of the enzyme was also inhibited by testosterone propionate (11 %),
progesterone (25%), and estradiol (15%) at their physiological concentrations.
The data obtained provides further evidence for the possible regulatory
effects of steroids, particulary DHEA, on G6PD activity.
http://mjiri.iums.ac.ir/article-1-1604-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
69
74
article
ANTI-ENDOTHELIAL CELL ANTIBODIES AND CIRCULATING IMMUNE COMPLEXES, A POSSIBLE PROGNOSTIC TOOL IN IDDM ANGIOPATHY
S RAFIEI
1
N MOSAFA
2
From the Department of Immunology and Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
52 patients suffering from ID D M (insulin-dependent diabetes mellitus)
were studied for anti-endothelial cell antibodies (AEA) and circulating
immune complexes (CIC).
20 had a high CI C level, and eight demonstrated AEA, of whom five had
retinopathy and three did not show any obvious vascular complication. It has
been shown that C3, C4 and CH50 levels were also decreased. AEA were
evaluated by indirect immunoflourescent technique, using rat pancreas
tissue as the antigen. To estimate the CIC level, PEG precipitating method
was used.
It was suggested that bydemonstratingAEJ', we will be able o evaluate
the prognosis ofIDDM, especially the long standing phase, with no vascular
complication.
http://mjiri.iums.ac.ir/article-1-1603-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
57
67
article
TETRA-N-BUTYLAMMONIUM FLUORIDE AS A NOVEL REAGENT FOR THE PREPARATION OF ACYCLO-NUCLEOSIDES. THE SYNTHESIS OF 9- [(2-HYDROXYETHOXY) METHYL] ADENINE, BITAMYCIN.
G.H HAKIMELAHI
1
F MOHANAZADEH
2
A KHALAFINEZHAD
3
M ZAKERINIA
4
From the Department of Chemistry' Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
From the Department of Internal Medicine
The synthesis of the title compound, bitamycin, by means of BU4NF
is described. This new antiviral drug was found to be one of the most powerful
and least toxic substances for antiviral therapy in man. The physical and
chemical behavior as well as the antiviral activities and clinical properties of
this compound were found to be significantly different from that reported by
Schaeffer, et al. Although the latter was claimed to have structure 1, we
found it to possess structure 2. BU4NF was proved to be an effective reagent
for the exclusive preparation of N(9)-alkylated products of purines. Condensation
reactions and deprotection of the acyl-protecting groups to yield
acyclo - nucleoside analogues were performed in a one step reaction.
http://mjiri.iums.ac.ir/article-1-1601-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
51
56
article
THE ROLE OF ALVEOLAR MACROPHAGES IN THE PRODUCTION OF COLONY –STIMULATING FACTOR BY THE LUNG
B GOLIAEI
1
A RABBANI
2
From the Institute of Biochemistry and Biophysics, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
The role of alveolar macrophages in the production of granulocyte/
macrophage colony-stimulating factor(s) by the rat lung was investigated.
Lavaged lungs, when incubated at proper weight per volume of culture
medium, produced the same amount of colony-stimulating factor as
unlavaged ones. Both lavaged and unlavaged lungs produced similar types
of colony-stimulating factor (s). Prolonged incubation of lavaged and
unlavaged lung tissues did not result in higher levels of activity beyond that
produced by 48 hrs of incubation. Alveolar macrophages recovered from the
lung did not produce colony-stimulating factors when they were cultured
unstimulated and under similar conditions as lung conditioned medium. The
results indicated that alveolar macrophages did not play a significant role in
colony stimulating factor (s) production by the lungs and when unstimulated,
they did not produce colony-stimulating factors directly.
http://mjiri.iums.ac.ir/article-1-1600-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
47
50
article
A SURVEY OF THE VIEWS OF IBN HINDU BASED ON RESEARCH ABOUT THE PROGRAMS OF MEDICAL INSTRUCTION
M FARHADI
1
From the Department of Otolaryngology, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
http://mjiri.iums.ac.ir/article-1-1599-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
43
45
article
THE DISTRIBUTION OF CLASS I HLA ANTIGENS IN 1000 NORMAL INDIVIDUALS IN KHORASAN PROVINCE
R FARID
1
H BARADARAN
2
B NIKBIN
3
I DAYHIMI
4
J TAVAKOLI
5
H AMINA
6
From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
From the" Department of Immunology. Faculty of Medicine, Tehran University of Medical Sciences, Tehran
From the" Department of Immunology. Faculty of Medicine, Tehran University of Medical Sciences, Tehran
From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
In this paper, the antigen and gene frequencies of class I HLA antigens
were evaluated in 1000 individuals in Khorasan province in northeast Iran,
and compared with statistics of other countries. The results and a general
discussion are presented.
http://mjiri.iums.ac.ir/article-1-1598-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
37
41
article
FREE USE OF LAPAROSCOPY IN THE MODERN MANAGEMENT OF ECTOPIC PREGNANCY
H DABIRASHRAFI
1
M BIGDELI
2
K MOHAMAD
3
A GHASSEMI NEJAD
4
S VAKILI
5
N MOGHADAMI TABRIZI
6
From the Endoscopy Clinic, Mirza Kouchek Khan Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Regarding the false negative results of culdocentesis, it is believed that
the protocol of B-hCG, sonography, D;C and free use of laparoscopy gives
more reliable information to the physician than the protocol of B-hCG,
sonography and culdocentesis. We used the former protocol on 50 patients
suspected of having ectopic pregnancy. The most common diagnoses were
EP (48%) and PID (16%), respectively. It seems, in contrary to reports from
abroad, among differential diagnosis of EP, ovarian cyst is not very common
in Iranian patients. One of the objectives of our protocol was to determine if
the use of laparoscopy with laparotomy causes an increase in the rate of
postoperative infection and elongates the stay of the patient in hospital. Thus
we compared our new protocol with the old protocol (gravindex, culdocentesis,
laparotomy) of management ofEPin our hospitaifrom the point of: 1- the
length of stay in hospital before and after laparotomy, and 2- the rate of
laparotomy infection. There was no statistical difference between the two
groups. The results of this comparison proved that laparoscopy when used
with laparotomy does not cause increased morbidity for the patients. The
most prominent feature of our special new protocol was the free use of
laparoscopy.1t is believed that the free use of laparoscopy has the following
advantages:
1- Elimination of false negative results of culdocentesis and encourage the
surgeon to perform essential laparotomies.
2- Identification of some cases of EP that can be managed conservatively.
3- Identification of the non-EP cases that should not be operated on.
http://mjiri.iums.ac.ir/article-1-1597-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
31
36
article
EXPERIENCE WITH 41 CASES OF RUPTURE OF URINARY BLADDER IN SHIRAZ
AA KHEZRI
1
From the Department of Urology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
41 patients with trauma to the urinary bladder are reviewed. 70 percent
were injured as a result of blunt trauma and 63 percent of patients had an
associated fracture of the pelvis. 82 percent of extra peritoneal ruptures were
associated with fracture of the pelvis. The most common cause of trauma was
car accident (56 percent), followed bywar injury (25 percent). The incidence
of intra and extra peritoneal rupture was nearly equal. The most common
presentation was abdominal pain and tenderness (48 percent), followed by
gross hematuria (37 percent). In 16 patients diagnosis was made by
retrograde cystography and in another six by intravenous pyelography. The
remaining patients were diagnosed by physical examination and diagnostic
laparotomy. All of the patients were treated by surgical repair . Mortality rate
was two percent.
http://mjiri.iums.ac.ir/article-1-1596-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
27
29
article
ENDEMIC GOITER IN BOYER-AHMAD
M KIMIAGAR
1
M.B YASSAI
2
M.T NAFARABADI
3
B SAMIMI
4
F AZIZI
5
From the Institute a/Nutrition and Endocrine Research Center, School a/Medicine, Shaheed Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
In order to investigate goiter prevalence in Boyer-Ahmad, an Iranian
tribal province, 87 families were randomly selected in Yasuj township and
Doruhan county. Clinical examination of the subjects disclosed 95% of
females and 87% of males over 6 years of age to be goitrous. Grade 2 goiter
had the highest prevalence among females. In males grade 1 b was the most
prevalent. Hormonal studies on a subsample did not show major abnormalities
but free T 3 index was increased significantly in subjects with grade 3
goiter compared to the goitrous and grade 2 groups (p < 0.01). Mean urinary
iodine excretion was33.9 ± 30.1 fLg/gcreatinine in Yasuj and23.95 ± 16.6 1 in
Ddruhan, indicating moderate to severe iodine deficiency. This study
documents goiter hyperendemicity in a Southern province not previously
acknowledged by national or international authorities.
http://mjiri.iums.ac.ir/article-1-1595-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
21
25
article
MAST CELLS IN THE TYMPANIC PART OF THE FACIAL NERVE IN CHRONIC OTITIS MEDIA WITHOUT ASSOCIATED FACIAL PARALYSIS
D DJERIC
1
2
From the Clinic of Otorhinolaryngology, University Clinical Center, Pasterova 2, 11000 Belgrade, Yugoslavia
The occurrence of mast cells is studied in the normal facial nerve and in
the facial nerve post mortem exam of patients with chronic suppurative otitis
media without associated facial paralysis. A small number of mast cells were
found in the normal facial nerve. These cells were usually located in close
proximity to the endoneural and epineural blood vessels. The number of
mast cells was increased in some areas of the facial nerve in the majority of
examined cases with chronic otitis media. In these cases, although the facial
nerve showed some signs of neuropathy, its function was normal.
http://mjiri.iums.ac.ir/article-1-1594-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
13
20
article
A SURVEY ON BREAST FEEDING IN THE ISLAMIC REPUBLIC OF IRAN
H MALEKAFZALI
1
E JAMSHID BEIGI
2
From the Department of Biostatistics and Epidemiology, School of Public Health, Tehran University of MedicalSciences' and the Ministry of Health and Medical Education, Tehran, Islamic Republic of Iran
In this paper breastfeeding was studied among 10240 urban and 10794
rural mothers, whose children were 18 to 23 months of age. The sample size
for rural and urban areas was equal, butin each province the cluster sampling
method was used proportional to the population of each district. The results
ofthe study show that between 17% to 28% of urban mothers in the provinces
have deprived their children from the minimum period of breastfeeding
namely 4 months. The results also show that between 51 % to 68% of mothers
have breastfed their children for at least one year. The percentage of mothers
who have breastfed their children for at least 1.5 years was in the range of
36% to 50%. On the other hand, 11 % to 22% of mothers residing in rural
areas have never breastfed their children or if so, the period has been less
than 4 months. The percentage of mothers who have breastfed their children
for at least one year is in the range of 61 to 79 percent. The percentage for
mothers who have breastfed their children for 1.5 years is between 47 to 66
percent.
The overall conclusion is that:
_ Rural mothers have more willingness to breastfeed their children than
urban mothers.
_ In all urban areas and in some rural areas, illiterate mothers have a higher
percentage of breastfeeding.
_ In some rural areas, literate mothers breastfed their sons more than their
daughters.
http://mjiri.iums.ac.ir/article-1-1593-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
9
12
article
EARLY COMPLICATIONS FOLLOWING RENAL TRANSPLANTATIONS
M HABERAL
1
From the Turkish Transplantation and Burn Foundation Hospital, Ankara-Turkey.
In this report, early complications (defined as those occurring within
one month post-operatively) following renal transplantation were evaluated
in 373 kidney transplantations in our department. The most common
complications as well as their relative frequency and method of management
are discussed.
http://mjiri.iums.ac.ir/article-1-1592-en.pdf
eng
Iran University of Medical Sciences
Medical Journal of The Islamic Republic of Iran (MJIRI)
1016-1430
2251-6840
1989-08
3
1
1
7
article
BACTERIAL ETIOLOGIES AND ANTIBIOTIC RESISTANCE IN SINUSITIS: A STUDY OF 264 CASES
M FARHADI
1
G BEHZADIAN NEJAD
2
B FATHOLLAHZADEH
3
N MOAZAMI
4
K HOLAKOEI
5
From the Department of Otolaryngology, Shaheed Rahnamon Hospital, Iran University of Medical Sciences, and the Tarbiat Modarres University, Tehran, Islamic Republic of Iran
Although inflammatory processes involving facial sinuses rarely develop
during childhood, these antrums due to their anatomic situations are
exposed to a variety of biologic and nonbiologic agents after birth.
Many types of bacteria are able to initiate inflammatory responses in
these antrums. Since effective management of these patients rests upon
demonstration of a specific pathogen and testing the organism(s) for
sensitivity to a variety of antimicrobial agents and due to the fact that there
are distinct epidemiological features in certain regions with respect to the
etiologies, we have randomly selected 264 patients with sinusitis from several
Tehran hospitals in order to estimate the frequency with which various
organisms may cause the condition and to evaluate antibiotic potency and
efficacy in eradicating the condition.
.
In 62.12 percent of cases the causative organisms could be cultured, in
32.3% of which more than one genus of bactria were isolated. The most
common bacterium in this setting was Staphylococcus aureus followed in
order by pneumococcus, enterobacteriaceae, haemophilus, pseudomonas
and branhamella. The sensitivity of these organisms to various antibiotics
(suitable in each case) were studied as well.
http://mjiri.iums.ac.ir/article-1-1591-en.pdf