@article{ author = {NOORBALA, HOSSEIN}, title = {USING THE INFERIOR MESENTERIC ARTERY FOR THE THIRD RENAL RE-TRANSPLANTATION: A CASE REPORT}, abstract ={A 32 year old man underwent renal transplantation for the third time. This procedure was performed in December 1994, using the kidney of a living unrelated donor. The first transplanted kidney remained in the body after rejection but the second one was removed due to trauma. End-to-end anastomosis of the renal artery to the inferior mesenteric artery was performed and the ureter was reimplanted to the bladder by Lich's technique. The post-op period went on quite normally and no surgical complication or renal rejection was observed. The transplanted kidney continues to function normally after more than 18 months. In reviewing the medical literature and papers, we did not find any report on using the inferior mesenteric artery for renal transplantation. . We recommend using the inferior mesenteric artery for renal re-transplantation in cases in which no other suitable artery exists. Since there would be.no need for aortic dissection and because of rough similarity between the diameters of the renal artery and inferior mesenteric artery, the potential risk of vascular complications would be less.}, Keywords = {Transplantation, renal;}, volume = {12}, Number = {1}, pages = {97-99}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1064-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1064-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {BASIRIDJAHROMI, SHAHINDOKHT and KHAKSAR, ALI ASGHAR and VAZIRIKASHANI, MOJGAN and ARSID, SAHBA}, title = {DISSEMINATED INFECTION DUE TO FUSARIUM SP. IN A PATIENT WI TH CHRONIC GRANULOMATOUS DISEASE}, abstract ={The present report discusses disseminated fusariosis in a 15 year old boy with chronic granulomatous disease (CGD). He was admitted to the Hazrat Rasool Acram Hospital in November 1995, with a chronic wound in the right ankle and buttock area. Antibacterial therapy was started, but there was no response. The patient was still febrile. Chest x-ray revealed parahilar lesions in both lungs. Tissue biopsy and broncho-alveolar lavage were performed and the specimens were sent to Pasteur Institute. In both specimens, Fusarium sp. was recognized as the pathologic agent by direct smear and culture techniques. The patient underwent antifungal therapy receiving amphotericin B and oral ketoconazole. The result of this treatment suggests that aggressive management of fusariosis offers the best chance of survival. This paper reports the first case of disseminated fusariosis in Iran.}, Keywords = {Fungal.infection, Fusarium sp., Chronic granulomatous disease}, volume = {12}, Number = {1}, pages = {93-96}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1063-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1063-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {NAGHIBZADEH, M}, title = {UNUSUAL AND RARE TERATOMAS OF THE HEAD AND NECK: A REPORT OF THREE CASES}, abstract ={Teratomas are bulky lesions that rarely occur in the head and neck regions.They are composed of tissues from all germ layers with varying degrees of differentiation. They arise from pluripotential stem cells and ectopic embryonic non-germ cells. The most common sites of occurrence in the head and neck are the cervical region and the nasopharynx. Three cases of these tumors are reported here that were found in the nasopharynx, cervical region and the base of the tongue.}, Keywords = {}, volume = {12}, Number = {1}, pages = {89-92}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1062-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1062-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {ABDOLLAHI, MOHAMMAD and JALALI, NASER and SHARIFZADEH, MOHAMMAD and KARIMI, GHOLAMREZA}, title = {ATTEMPTED SUICIDE BY INSULIN INJECTI ON TREATED WITH HYPERTONIC GLUCOSE SOLUTION}, abstract ={A young woman with no history of diabetes tried to commit suicide by injecting 2800 units of subcutaneous NPH insulin. She was transferred to Loghman Hospital within 12 hours. The main clinical symptom was continuous seizure activity which was resistant to all forms of routine drug therapy. The patient was treated with intravenous hypertonic glucose (50%) followed by continuous glucose (10%) infusion. The patient was discharged from the hospital after 8 days without any sequelae.}, Keywords = {Insulin, Overdose, Suicide.}, volume = {12}, Number = {1}, pages = {85-87}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1061-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1061-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {AJUDANI, TJ and GHARAVI, M and BASTANI, B}, title = {PRIMARY HYPER OXALURIA: REPORT OF FOUR CASES AND REVIEW OF THE LITERATURE}, abstract ={In this paper we will present four cases of primary hyperoxaluria. All patients had a significant past medical history of polyuria (with or without microscopic hematuria) and polydypsia. All patients had a family history of their parents being cousins. Initial evaluation of all patients by ultrasound and plain abdominal films revealed nephrocalcinosis. Their clinical courses showed gradual loss of renal function over the follow-up years. We will also review primary hyperoxalurias and their management in this report.}, Keywords = {Oxalate, hyperoxaluria, oxalosis, renal failure, transplantation}, volume = {12}, Number = {1}, pages = {79-84}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1060-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1060-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {SABRI, MOHAMMAD REZA and ALAVIAN-GHAVANINI, AHMAD}, title = {BENIGN EXTREME HYPERBILIRUBINEMIA IN A 9 YEAR-OLD GIRL WITH SICKLE-THALASSEMIA AND THE PROBABLE ROLE OF HBF IN PREDICTING THE OUTCOME}, abstract ={Hepatic dysfunction is a frequent manifestation in patients with sickle cell anemia. It is usually a multifactorial process. A rare benign form of extreme hyperbilirubinemia, presumably due to intrahepatic sickling, may be the cause. We report a 9 year old girl with sickle-thalassemia hemoglo binopathy, presenting with profound jaundice. Sickle cell disease is often mild in the Iranian population due to relatively higher levels of HbF, suggesting that the βs gene is associated with a gene capable of producing high levels of HbF. Moreover, sickle thalassemia disease is generally milder than sickle cell disease. In this patient, the previous electrophoresis had shown a relatively high HbF level (34.3%). This may account for the benign course of hyperbilirubinemia and no need for blood transfusion in this case, despite the majority of previous reports}, Keywords = {Sickle-thalassemia, Intrahepatic sickling, Fetal hemoglobin.}, volume = {12}, Number = {1}, pages = {75-78}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1051-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1051-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {FIROOZBAKHSH, KEIKHOSROW and ORCUIT, FRED V.}, title = {THE EFFECTS OF ANTERIOR DISCECTOMY AND INTERPOSITION AL IMPLANT UPON LUMBAR MOTION SEGMENT STABILITY}, abstract ={The cadaver spine motion segment behavior under torsional load was evaluated with the disc intact, with partial anterior discectomy and with spacer insertion. The results of this study explain how anterior lumbar discectomy and interbody fusion (ALIF) affects the torsional stability of the motion segment. The pseudarthrosis rate of the anterior lumbar discectomy and interbody fusion (ALIF) is known to vary with leveL Therefore fifteen fresh human cadaveric degenerated discs at L3-4, L4-5, and L5-S1 levels were loaded in torsion: intact after anterior discectomy and, after spacer interposition and removaL Torsional rigidity of intactL5-S 1 was greater than L3-4 (41 %) orL4-5 (53%). Anterior discectomy significantly decreased the torsional rigidity compared to intact: L3-4 (73%) L4-5 (48%) and L5-S1 (55%). Interpositioning of spacer partially restored the torsional stability compared to discectomy: L3-4 (22%) L4- 5 (18%) and L5-S1 (38%). In conclusion, L5-S 1 degenerated discs are rotationally more stable than L3- 4 or L4-5. Anterior discectomy significantly increases torsional flexibility. Spacer interposition partially restores the disc's torsional stability which is most prominent at the L5-S 1 leveL Increased rotational flexibility seems related to pseudarthrosis rate.}, Keywords = {Lumbar spine, Biomechanics, Rotational instability, Arthrodesis.}, volume = {12}, Number = {1}, pages = {71-74}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1050-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1050-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {NIKNAFS, B and TAKI, TM and REZAZADEH, M and ALIMOHAMMADIAN, MH}, title = {MORPHOLOGICA L STUDY OF MOUSE (BALB/c) THYMUS A FTER HIGH A ND LOW DOSE DEXA METHA SONE TREATMENT}, abstract ={Dexamethasone induces thymic atrophy and thymocyte apoptosis. In the present study histological and ultrastructural changes which occur in the thymus of the mouse (BALB/c) following treatment with high (20 mg/kg) and low (8 mg/kg) doses of dexamethasone were investigated. In low dose treated mice, apoptotic cells were observed focally and localized mainly in thymic nurse cells (T.N.C.). A zone of intact thymocytes was formed in the medulla of animals receiving 20 mg/kg of dexamethasone as well as an increase in trans-endothelial vesicles and a decrease in the size of the vesicles in the cortical capillaries. The enveloped thymocytes within thymic nurse cells respond to dexamethasone through apoptosis, and these changes were seen to be more severe in mice treated with high doses of dexamethasone. The formation of apoptotic cells in the thymus caused by low dose dexamethasone mimics the physiological process of cell death. Differential effects of low dose and high dose dexamethasone may have pharmacological and immunological implications.}, Keywords = {}, volume = {12}, Number = {1}, pages = {65-69}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1049-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1049-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {MALEKIDIZAJI, N and GARJANI, A and PYNE, S}, title = {SPHINGOMYELIN METABOLITES A S SECOND MESSENGERS IN AIRWAY SMOOTH MUSCL E CELL P ROLIFERATION}, abstract ={Sphingolipid metabolism was examined in guinea-pig airway smooth muscle cells stimulated by platelet-derived growth factor (PDGF) and 4β-phorbol 12- myristate 13-acetate (PMA), as mitogens and bradykinin (BK) as non-mitogen. Stimulation of the cells by PMA and PDGF for 60 min. at 37°C induced the following changes in sphingolipid metabolites: in cells prelabeled with PH] palmitate, a 1.2 fold increase in radio-labeled sphingosine, a concomitant 20% decrease in radio-labeled ceramide and no significant change in sphingomyelin level. Stimulation of the cells by BK induced no changes in sphingolipid levels at any time tested. This study demonstrates the existence of a "sphingomyelin cycle" in airway smooth muscle cells. Such sphingolipid cycles may function in a signal transduction pathway and in cellular proliferation.}, Keywords = {}, volume = {12}, Number = {1}, pages = {57-63}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1048-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1048-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {VODJGANI, M and AZADI, F and HAJATI, J and KARIMIAN, M}, title = {EFFECT OF β-HUMAN CHORIONIC GONADOTROPIN (β-HCG) ON NEUTROPHIL FUNCTIONS}, abstract ={Many findings point to the presence of a close relationship between the immune, endocrine and neurologic systems. For example the suppressive effects of β-human chorionic gonadotropin (β-HCG) on IL-l production, the potentiative effect of enkephalins on lymphocyte functions and the suppressive effect of leuteinizing hormone (LH) on natural killer (NK) cell activities have been clearly established. In this regard we have studied the effects of β-HCG on neutrophil function in vitro. This study was performed on 28 peripheral blood neutrophil samples (14 as test and 14 as control), by incubating neutrophil preparations with bacteria in the presence or absence of the hormone for one hour at 37°C. The results indicated that with 20 IU/mL of hormone, the total and intracellular bactericidal activities of neutrophils were• significantly increased (p<0.05), but the phagocytic activity remained unchanged.}, Keywords = {Gonadotropin, human chorionic; n-eutrophil function}, volume = {12}, Number = {1}, pages = {53-55}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1047-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1047-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {SHAHCHERAGHI, FERESHTEH and ESLAMI, MOHAMMAD BAGHER and TABARAIE, BAHMAN and BEHZADIAN-NEJAD, GHORBAN}, title = {ISOLATION AND PURIFICATION OF MAJOR OUTER MEMBRANE PROTEINS FROM BRUCELLA ABORTUS S-99}, abstract ={Isolation and purification of major outer membrane proteins (OMP) from the cell wall envelope of Brucella abortus S-99 were achieved by sonication, solubilization and membrane fractionation in the presence of non-ionic detergent (Tx-100) and lysozyme treatments, followed by ultracentrifugation. The crude OMP was treated with trypsin to free the preparation from any other protein contaminants. The OMP preparation was purified by column chromatography on Sephacryl S-200. Three major symmetrical peaks emerged from the column with kav values of 1. 81, 2.42 and 2.56 in succession in addition to a few closely related minor peaks. Characterization of crude OMP on SDS-PAGE showed 13 protein bands. The three major peaks 1,2 and 3 were subjected to SDS-PAGE separately and the molecular weights of peaks 2 and 3 were calculated to be 26 and 38 kDa, respectively and the first peak was further resolved into two subfractions with molecular weights of 62 and 67 kDa. However, after treatment of OMP with trypsin the number of bands were reduced to one prominent band with a molecular weight of 38 kDa and a thinner band of 41 kDa.}, Keywords = {}, volume = {12}, Number = {1}, pages = {47-51}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1046-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1046-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {ABBASZADEGAN, MORTEZA and EMAMI, ALI and FARID, REZA and GERBA, CHARLES}, title = {OCCURRENCE OF VIRUSES AND P RO TOZOAN PARASI TES IN SURFACE, GROUND AND TREATED WATER IN THE CI TY OF MASHHAD, IRAN}, abstract ={A research plan was developed to evaluate the occurrence of enteroviruses, giardia cysts and cryptosporidium oocysts in thirty-five different sites in the city of Mashhad, Iran. The occurrence of these pathogenic microorganisms was evaluated to investigate a possible health risk in the communities. For the detection of enteroviruses in water samples, the conventional method of cell culture, using Buffalo Green Monkey (BGM) cell line, was used. The minimum sample volume for viruses was 500 liters, collected using a positively charged MK cartridge filter, eluted with beef extract and concentrated by organic flocculation. The method of detection for cysts and oocysts relied on microscopic observation of water samples by the immunofluorescence assay (IFA). For this study, water samples were collected using a cartridge filter, eluted by washing the filter using a detergentbased medium, concentrated by centrifugation, clarified by a percoll-sucrose density gradient, stained by an indirect fluorescent antibody, and examined by epifluorescence microscopy. A total of seventy surface, ground or treated water samples were collected from 35 different sites in the metropolitan city of Mashhad. Thirty-five samples were assayed for the presence of enteroviruses by cell culture and 35 samples were assayed by IFA technique for the detection of cysts and oocysts. Two surface water samples tested positive for virus presence and three surface water samples tested positive for giardia cysts. Based on the results of this research project, no microbial contamination of finished water was documented, suggesting proper treatment of surface water at the time of sampling.}, Keywords = {}, volume = {12}, Number = {1}, pages = {41-45}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1045-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1045-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {EMAMI, MJ and ABDINEJAD, F and KHODABKHSHI, S and AMINI, M and NASERI, B}, title = {THE NORMAL CARRYING ANGLE OF THE ELBOW IN SHIRAZ}, abstract ={The normal carrying angle in Shiraz population was measured on the basis of sex and age. The right elbow angle of 4266 cases was examined from birth to 30 years old. This study found the carrying angle in 2540 females to be 7.20 (range 2-19) and in 1726 males to be 6.40 (range 2-11), a 0.80 difference. A significant difference (p= 0.05) was found in relation to age. There is a gradual increase in the carrying angle with skeletal maturation.}, Keywords = {Angle, Elbow}, volume = {12}, Number = {1}, pages = {37-39}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1044-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1044-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {JANGHORBANI, MOHSEN and NAKHAI, HAMID REZA}, title = {EFFECT OF PASSIVE SMOKING DURING PREGNANCY ON WEIGHT, LENG TH AND CRANIAL CIRCUMFERENCE AT BIRTH IN KERMAN, IRAN}, abstract ={Passive smoking (PS), a well-known health risk, is the major source of indoor pollution. There is some inconsistent evidence that PS during pregnancy may increase the risk of low birth weight. The aim of the present study was to determine the effects of PS exposure during pregnancy on weight, length and cranial circumference at birth of babies born to women who have described themselves as nonsmokers, in Kerman, Iran. A random sample of 702 admitted women aged 11 to 50 years [mean (standard deviation) 26.5 (6.1)] who delivered a live full-term singleton baby without apparent malformation during the six consecutive months from June to December 1994 were interviewed on the second day post-partum and asked about smoking in all household members. They comprised about 36.4% of total deliveries in Bahonar Kerman Medical School Hospital during this period. All women were nonsmokers, 278 (39.6%) were passive smokers while 424 (60.4%) were not exposed to tobacco smoke. Potential confounders, including fetal gender, maternal age, parity, weight gain, complications during pregnancy, maternal education, birth interval and gestation were adjusted for by multiple linear regression analysis. Infants born to passive smokers were on the average 22 gr. lighter than those born to nonsmokers, albeit this difference was not statistically significant (p = 0.56) [95% confidence interval (CI): -51, 95.7]. A mean reduction of 0.04 cm [95% CI: -0.19,0.27] in birth length and 0.05 cm [95%CI: -0.12, 0.22) in cranial circumference was found. In multiple linear regression model, exposure to PS during pregnancy did not show any effect on weight, length and cranial circumference at birth after adjusting for confounding variables.}, Keywords = {Low birthweight, passive, sidestream, second-hand, environmental, smoking, epidemiology, Iran.}, volume = {12}, Number = {1}, pages = {31-36}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1043-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1043-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {KHALILI, MA and CLOWER, BR and IWASA, K}, title = {ANATOMIC CORRELATION BE TWEEN INTIMAL PATHOLOGY AND CEREBRAL VASOSPASM FOLLOWING SUBARACHNOID HEMORRHAGE}, abstract ={Subarachnoid hemorrhage (SAH) resulting from a ruptured intracranial aneurysm can induce cerebral vasospasm with subsequent reduction in cerebral blood flow (CBF). The present study examines the pathological alterations in the wall of human cerebral arteries at autopsy, especially with regard to intimal pathology, following aneurysmal SAH. Arterial segments from the circle of Willis were fixed in 10% formalin, embedded in paraffin, sectioned at 4µ and stained with hematoxylin-eosin or toluidine blue. Similar numbers of sectioned vessels were also examined in control material. The areas of intima, lumen and the length of internal elastic lamina were compared witth those from control sections. Pathological changes such as myonecrosis and fibrosis in muscular layers associated with a possible loss of compliance and elasticity of the vessel wall were also noted. The average luminal area decreased to 56.8% ± 12.5% compared to comparable controls (p<0.005). The tunica intima was the most abnormal component of the arterial wall with cellular proliferation which was made up predominantly of collagen fibers and loose fibroblasts. These pathological findings are mainly due to myonecrotic changes and intimal proliferation with the resultant luminal constriction and CBF impairment which might explain the high incidence of cerebral infarction in cases of SAH.}, Keywords = {Subarachnoid Hemorrhage, Cerebral Vasospasm, Intimal Pathology.}, volume = {12}, Number = {1}, pages = {25-29}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1042-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1042-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {TABRIZCHEE, H and MASOOMIAN, M and AHANI, F and ZARE, MS}, title = {THE PATTERN OF MALIGNANT TUMORS IN KERMAN PROVINCE}, abstract ={This investigation was done in Kennan from March 1989 to March 1993 to study the epidemiology of cancers in this province and to compare the results with a previous study performed in this area and some available statistics. A total number of 288 1 new cases of malignancy were registered and the crude relative frequency of cancers was studied. Gastric cancer with a frequency of 9.7%, malignant lymphoma with 8.8% and leukemia with 6.8% were the three most common malignancies in this province, excluding skin malignancy. Keywords: Cancer epidemiology, Gastric carcinoma, Malignant lymphoma, Breast carcinoma}, Keywords = {}, volume = {12}, Number = {1}, pages = {19-23}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1041-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1041-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {RAFIEI, SEYYED MOHAMMAD}, title = {HOW PHYSICIANS MANAGE SEIZURE DISORDERS IN INFANTS AND CHILDREN: A PILOT STUDY}, abstract ={To see which medical specialties usually manage seizure disorders in infants and children, a random survey was done among 105 such patients referred. These patients were most frequently seen by a pediatrician (n= 44, 4 1.9%), general practitioner (n=34, 32.4%), and hospital house staff of general and pediatric emergency rooms (n= 2, 19%) in the area surveyed. A correct diagnosis of seizure disorder was achieved in 87.6% and 87.6% of the patients were managed correctly by various medical specialties. Several "seizure mimickers" were mistaken for seizure, i.e., breath holding spells, syncope and night terrors. It is concluded that various medical specialties are involved in the care of infants and children with seizure disorder, and further effort on the education of these specialties would avoid mis-management of such patients.}, Keywords = {Seizure disorder (SD), Breath-holding spells ( BHS), Syncope, Night terrors (NT)}, volume = {12}, Number = {1}, pages = {15-17}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1040-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1040-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {BABADIZAVANDY, ESMAT and SEYYEDIALAVI, GHODSIH and CORDI, MASOMEH}, title = {THE EFFECT OF C ALCIUM SUPPLEMENTATION IN THE PREVENTION OF HYPERTENSIVE DISORDERS OF PREGN ANCY IN NULLIPAROUS WOMEN}, abstract ={The purpose of this prospective study was to determine the effect of calcium supplementation in the incidence of hypertensive disorders of pregnancy (gestational hypertension and pre-eclampsia) in nulliparous and high risk women. 300 pregnant women in the 24th week of gestation at the beginning of the study were entered into a double-blind randomized trial. 143 of them who had a positive roll-over test and hypocalciuria at the 28-32nd week of gestation were enrolled for the study. Subjects were assigned to receive 2 g per day of elemental calcium (52 women) or placebo (61 women) from the 28-32nd week of pregnancy until delivery. Results showed that 11.4% of calcium-treated subjects developed gestational hypertension, compared to 31.2% of the placebo group. The rate of hypertensive disorders of pregnancy was also higher in the placebo group (35.6% vs 11.4%, p<0.01).}, Keywords = {}, volume = {12}, Number = {1}, pages = {11-14}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1039-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1039-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {JAHANFAR, SHAYESTEH and EDEN, JOHN A. and WANG, XING L and WlLCKEN, DAVID E.L and NGUYEN, TUAN}, title = {THE EFFECT OF GENETIC AL AND ENVIRONMENTAL FACTORS ON LIPIDS: A TWIN STUDY}, abstract ={To assess the relative contribution of genetic and environmental factors (particularly androgens) on circulating levels of lipid fractions, serum androgen and lipid fractions were measured in 34 pairs of female-female twins aged from 15- 45 years, some of whom were discordant for polycystic ovary syndrome (PCOS) diagnosed by ultrasound. Nineteen pairs were monozygotic twins (MZ) and 15 pairs were dizygotic twins (DZ). Five pairs of MZ and 6 pairs of DZ were discordant for scan-PC a. We measured serum concentrations of total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), triglycerides (TRIG), lipoprotein (a) [LP(a)], and apolipoprotein B (apo B). Also, testosterone (T), dehydroepiandrosterone sulphate (DHEAS), sex hormone binding globulin (SHBG) and 3a-androstanediol glucuronide (3a-diol G) levels were measured. Transabdominal ultrasound was performed. Serum levels of TC, HDL-C, TRIG, LP(a) and apo B in the twins with PCO were not significantly different from the levels in their matched co-twins with normal ovaries. There were no significant correlations between androgen-hormones including T, DHEAS and 3a-diol G with any of the lipid measurements. Body mass index (BMI) was positively correlated with TRIG, LP(a) (both p<0.05) and negatively correlated with HDLC (p<0.001). SHBG was negatively correlated with TRIG and LP(a) and positively associated with HDL-C (p<0.05). Insulin was significantly correlated with TRIG (p<0.001) and negatively with HDL-C (p<0.01). The MZ intraclass correlation exceeded that of the DZ for all the lipid variables measured. The heritability estimates for LP(a), apo B, TC and HDL-C were 0.95, 0.56, 0.48 and 0.54, respectively. However, the intraclass correlation coefficient for TRIG was not significantly different between MZ and DZ but maximum likelihood analysis indicated that at least 10% of the variance of circulating TRIG concentration is determined by genetic factors. We conclude that twins discordant for pcas do not have significantly different lipid profiles. We were unable to show any significant effect of androgens on the lipid fractions measured. The results confirm that levels of LP(a), HDL-C, TC and apo B are under significant genetic control and that this is particularly so for LP(a). However, only 10% of the variation in TRIG levels could be attributed to genetic influences after controlling for age and obesity. Increase in BMI and insulin had a significant adverse effect on the lipid profile in these female twins, effects which may enhance coronary risk.}, Keywords = {Polycystic ovary syndrome, androgens. lipids, twin study.}, volume = {12}, Number = {1}, pages = {5-9}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1038-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1038-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} } @article{ author = {ZEINALOO, ALI AKBAR and SHAKIBI, JG and A. SHAH-MOHAMMADI, A}, title = {STUDY OF LATE POTENTIALS IN PEDIATRIC PATIENTS AFTER OP EN HEART SURGERY}, abstract ={This study was conducted to assess the incidence of abnormalities of ventricular depolarization (late potentials) in children with sinus rhythm after open heart surgery and their relation to spontaneous ventricular tachycardia. Open heart surgery, particularly operations involving ventriculotomy, may predispose patients to the development of ventricular tachycardia (VT) or ventricular fibrillation (VF). Previous studies on children with right bundle branch block (RBBB) have shown that late potentials may be a risk factor for developing VT or VF following open heart surgery. After corrective surgery for congenital heart defects, scars may create fractionation and delay of the electrical signals in the heart muscle, providing a substrate for arrhythmias and sudden cardiac death. To find normal values of signal averaged EKG (SA-EKG) indices in children and their changes following open heart surgery, we studied 20 normal children and 20 children with congenital heart disease (CHD) following total correction of heart defects without ventriculotomy. All patients were in normal sinus rhythm and did not have RBBB. The mean age was 8.8±2.6 years for the control group and K 1±2.1 years for the operated patients. SA -EKG was performed for the operated group on the day before and on the 2nd and 4th days after operation. Noise level was less than 1 microvolt. The SA-EKG parameter values were as follows: control group: filtered QRS-duration 40Hz (F. QRS-d), 84.2±9.5 ms high frequency low amplitude signals (HFLA) , 18.9±9.5 ms rootmean square 40 (RMS 40), 181.0±89.4 µv patients: F.QRS-d, 97.2±19.3*, 116.4±21.2* and 122.2±220.4before operation, 2nd day post-op and 4th day post-op, respectively HFLA, 205±22.3, 8.9±7.0*, and 15.4±16.4ms,respectively RMS40, 146.4±11O.9,92.1±65.9,and 112.8±60.3, respectively. Values marked with an asterisk are statistically significant. Except for a significant difference between the QRS duration of normal children and pre-op values of operated patients (p<0.05), there was no remarkable difference between the SA-EKG values pre- and postoperatively. This study in which there was no RBBB, contrary to previous studies, shows that SA-EKG indices are not a predictive value for VT or VF postoperatively. Increased thickness of the ventricular myocardium may be a reason for the increased QRS duration before operation.}, Keywords = {Late potentials, Ventricular arrhythmias, Operated congenital heart defect in children, Signal-averaged electrocardiography.}, volume = {12}, Number = {1}, pages = {1-4}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1037-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1037-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1998} }