@article{ author = {AL-SHARIFI, MA}, title = {N-GLUCOSIDES: NEW PHASE-II METABOLITES OF TWO BARBITURATES}, abstract ={The new phase-II N-glucoside metabolites of butobarbitone and pentobarbitone are identified and quantified in human urine after single doses of these drugs. The identification and quantification of these metabolites were carried out by mass spectroscopy technique (accurate mass measurement and high voltage scanning). It was found that the butobarbitone N-glucoside comprised 26% of the dose with tl/2= 44h, while the pentobarbitone N-glucoside was 43% with t1/2= 40h.}, Keywords = {}, volume = {6}, Number = {1}, pages = {63-66}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1511-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1511-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {GHANAAT, JAVAD}, title = {EVALUATION OF CEFTAZIDIME ANTIMICROBIAL ACTIVITY IN INFECTIONS CAUSED BY BURNS}, abstract ={In vitro evaluation of ceftazidime antimicrobial activity in infections caused by burn and its comparison to the other antibiotics is presented. In vitro tests for susceptibility to ceftazidime and other antibiotics were carried out on 744 bacterial strains collected from burn infections. The results have shown that generally ceftazidime was more active against Pseudomollas aeruginosa and other gram-negative bacilli like Klebsiella pneumolliae, Escherichia coli, and Proteus than amikacin, gentamicin, tobramycin, carbenicillin, kanamycin, and streptomycin in terms of potency and activity. In addition, and according to our in vitro studies we suggest that ceftazidime could be considered a valuable alternative to other antibiotics in the treatment of burn infections caused by P. aeruginosa and other gramnegative bacilli.}, Keywords = {}, volume = {6}, Number = {1}, pages = {59-62}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1510-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1510-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {AL-SAADI, D and SNEADER, WE}, title = {A NEW BIOLOGICAL SCREENING SYSTEM FOR LOCAL ANAESTHETICS BY INHIBITION MOBILITY OF TETRAHYMENA PYRIFORMIS}, abstract ={An alternative in vitro approach to drug screening has been the use of human cell cultures for antiviral agents and microbial cell cultures for the assessment of the carcinogenic potential of selected compounds. A number of protozoan species have been also used as drug screens for anti-protozoal agents. The ciliated protozoan Tetrahymena pyriformis species has been widely utilised as a drug screen for a variety of pharmacologically active agents. Accordingly, it was decided to investigate whether T. pyriformis could be used as a preliminary drug screen for evaluation of the local anaesthetic activity and duration of action of certain commercially available local anaesthetics. In this communication, the results of this new in vitro biological drug screen are reported. It is based on the complete protozoan cell immobilisation by the anaesthetic solution. A positive inverse correlation was observed between the lowest concentration (minimum inhibitory concentration=MIC) that wholly inhibits the mobility of all cells of T. pyriformis and the duration of action of the test compounds. Generally, MIC was high for the short-acting anaesthetics and low for the long-acting ones. The results suggest the suitability of this new microbiological assay system for the evaluation of local anaesthetic activity and duration of action and possibly irritancy and toxicity of other local anaesthetics as well as potentially active therapeutic agents which possess surface activity.}, Keywords = {}, volume = {6}, Number = {1}, pages = {55-58}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1509-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1509-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {NASSIRI, P and JAAFARI, M and GOLBABAI, F and MAHMOODI, M}, title = {DETERMINATION OF THE OPTIMUM HEAT STRESS INDEX AT A FOUNDRY}, abstract ={This paper presents a case study to determine the efficiency of the currently used heat stress indices in correlation with wet bulb globe temperature (WBGT) as a permissible index at a foundry plant and to evaluate the extent of the physiological responses such as heart rate and body temperature in correlation with heat stress indices. The field consisted of a foundry plant where a shift work was in operation. The results indicated that wet globe temperature (WGT), corrected effective temperature (CET), and predicted four-hour sweat rate (P4SR) indices have the best correlation with WBGT index respectively, and P4SR and CET indices correlate well with physiological responses more successfully than WBGT does in hot-dry conditions, CET index gives the best correlation with body temperature while P4SR is the most accurate with the heart rate.}, Keywords = {}, volume = {6}, Number = {1}, pages = {49-53}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1508-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1508-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {RABBANI, AZRA and NAVAB, ROYA and GOLIAEI, BAHRAM}, title = {CHROMOSOMAL PROTEINS IN PULMONARY ALVEOLAR MACROPHAGES}, abstract ={In this study the nature of chromosomal proteins, his tones and nonhistone in resident alveolar macrophages was investigated in comparison to peritoneal neutrophils and calf thymus proteins. Cells were obtained by lavaging the lung and after purity determination they were subjected to fractional extraction procedures. Proteins were then analysed on SDS polyacrylamide gels and densitometric scans were obtained. The results show that in macrophages, the pattern of histone and nonhistone proteins were similar to thymus proteins, two distinct and specific proteins HI° and HMGI4b and also a protein with a molecular weight of I2kd (Hx) were present. These data suggest a different chromatin protein pattern in pulmonary alveolar macrophages.}, Keywords = {}, volume = {6}, Number = {1}, pages = {45-48}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1507-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1507-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {NOUHI, FEREYDOUN and FARIDHOSSEINI, REZA and BASTANHAQ, MOHAMMAD HASSAN and DADGAR, ALI ASGHAR}, title = {MANAGEMENT OF HEATSTROKE IN 304 PATIENTS DURING HAJJ PILGRIMAGE}, abstract ={Three hundred and four patients with different degrees of heatstroke were treated by the Hajj medical team of the Islamic Republic of Iran. Four percent of the patients had associated diseases. A simple method using immersion in iced tap water was used for management of heatstroke. Advantages and wide applicability of the technique are described, achieving good results without using sophisticated and expensive means.}, Keywords = {}, volume = {6}, Number = {1}, pages = {43-44}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1506-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1506-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {MOHAGHEGH, M}, title = {RAZI AND HIS BOOK ON AL-TIN AL NISHABURI}, abstract ={}, Keywords = {}, volume = {6}, Number = {1}, pages = {39-41}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1505-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1505-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {NAZERY, IRAJ and ESLAMI, MASSOUD}, title = {BRUCELLA MELLITENSIS ENDOCARDITIS: DIAGNOSIS AND TREATMENT IN SIX ADULT PATIENTS.}, abstract ={Brucella endocarditis is an uncommon but not rare manifestation of brucellosis in our country. We report six adult patients aged 20 to 45 years. Two of our patients were female, and this is the first time that Brucella endocarditis was reported in adult females. In five cases, aortic valve replacement was performed in addition to combined antibiotic therapy. One of them died due to immediate complication of cardiac surgery, but the others had an excellent recovery. Our study shows that medical treatment is not sufficient for Brucella mellitensis endocarditis, and urgent cardiac valve replacement must be considered. The prognosis will not be poor with combined medical and surgical therapy.}, Keywords = {}, volume = {6}, Number = {1}, pages = {35-37}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1504-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1504-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {RAZZAGHIAZAR, M and AHMADI, J and RABBANI, A and NEZAKATGOO, N and MOSAVATI, M and SHAFEGHATY, Y}, title = {EXPERIENCE WITH ADRENOCORTICAL TUMORS IN CHILDREN: A REPORT OF ELEVEN CASES}, abstract ={During a period of IS years from 1975 to 1989, eleven children with adrenocortical tumors were managed with relatively favorable results in our center. Despite its rarity in the pediatric age group, our series is one of the largest reported in the literature in the given period of time. All of our 11 patients presented with hyperfunction of the adrenal cortex. Virilization alone was the most frequent presenting sign, occurring in eight patients. Two patients suffered from Cushing's syndrome and one patient had mixed presentation of Cushing's syndrome and virilization. There were six females and five males in the series. Four of five males presented before two years of age. Female patients presented at an older age. In nine out of 11 patients the tumor was on the right side. Mean age at presentation was 3.55 years. Serum levels of testosterone, dehydroepiandrosterone (DHEA), and cortisol were elevated in all cases tested and apparently are superior alternatives to more traditional measurements of urinary 17- ketosteroids and 17-hydroxy corticosteroids. The majority of our cases were investigated by the employment of IVP and sonography. In one patient I131 iodocholesterol scintigraphy was used. Transabdominal approach through a transverse upper abdominal incision is recommended. In this series only one intraoperative complication was encountered. At a mean follow-up of five years, 10 out of 11 children were alive and had no evidence of tumor recurrence. In all patients pre-operative steroid replacement was essential. Contrary to our pathologic reports «six adenoma, three carcinoma, and two undetermined» we found favorable outcomes in the majority of our patients. We conclude that in contradiction to previous concensus, most pediatric adrenocortical tumors will behave as a benign neoplasm and that the size and weight are the only morphologic predictors of their biological behavior.}, Keywords = {}, volume = {6}, Number = {1}, pages = {29-34}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1503-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1503-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {FROOZANI, MD and MONFARED, EXIR and NOURMOHAMMADI, I}, title = {MATERNAL AND NEWBORN PROTEIN STATUS AT DELIVERY IN A PUBLIC AND A PRIVATE MATERNITY HOSPITAL IN TEHRAN}, abstract ={Protein status of 194 pregnant women and their newborn at a public and a private maternity hospital in Tehran was studied. Blood samples were taken from all women before delivery and from cords at delivery of the placenta. The following determinations were made: total serum protein, protein fractions, creatinine and urea. In the private group, significantly higher maternal mean values were found for serum urea (P<0.01), albumin (P<0.05) and B -globulin (P<0.01) when compared to the public group. In cord blood, the mean serum creatinine (P<0.01) and urea (P<0.02) were significantly higher and B -globulin (P<O.05) was lower in the private group when compared to the public group. It can be concluded that socio-economic status clearly affects maternal nutrition, thereby affecting to some extent the nutritional status of the fetus.}, Keywords = {}, volume = {6}, Number = {1}, pages = {25-27}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1502-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1502-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {TABARESTANI, MOJTABA}, title = {HEMOPHAGOCYTIC SYNDROME IN TYPHOID FEVER AND BRUCELLOSIS}, abstract ={Hemophagocytic syndrome is a non-malignant process that is characterized clinically by fever, hepatomegaly, splenomegaly, pancytopenia in peripheral blood, and reactive histiocytes in the bone marrow. Bacterial infectious diseases like typhoid fever and brucellosis and viral infections including CMV, herpes viruses, and Epstein-Barr virus are diagnosed as the cause of this syndrome. In this paper we present six patients with hemophagocytic syndrome who had blood culture or bone marrow culture, and or serology positive for typhoid fever or brucellosis. This is the first report of hemophagocytic syndrome in Iran.}, Keywords = {}, volume = {6}, Number = {1}, pages = {21-24}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1501-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1501-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {RAJABIAN, R and GHIASSI, T and HAGHIGHI, F}, title = {PAPILLARY THYROID CARCINOMA IN MASHHAD}, abstract ={Thyroid cancer is the most common endocrine malignancy. This study surveys the pathologic characteristics of thyroid cancerin Mashhad and study of papillary carcinoma in more detail. In this retrospective study, 108 out of 197 cases of thyroid cancer were papillary in type (55%), with female to male ratio of 1.91 which is lower than current reports. The age at the time of diagnosis ranged from five to 78. Mean age for females was 36 and for males was 38.45 years. We hope that this study will stimulate physicians to reevaluate their thoughts about thyroid cancer and try to recognize such patients at an earlier stage in the course of their disease.}, Keywords = {}, volume = {6}, Number = {1}, pages = {17-19}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1500-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1500-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {FOROOTAN, HOSSEIN}, title = {COLORECTAL POLYPS: EVALUATION IN TWO YEARS}, abstract ={From June 1989, to June 1991, 58 patients with GI polyps were reviewed. Except two patients who had multiple polyps, 56 had only one polyp. The size of polyps were 0.5 to 3 em in diameter. 51 (75%) of polyps were located in the rectosigmoid region, 25 (37%) were in the rectum and 26 (38%) in the sigmoid. (Seventeen) (25%) polyps (two in right colon, four in transverse, and 11 in descending colon) were located in other regions. Patients were between nine months to 70 years old. 14 polyps were reported to be inflammatory, and 17 adenomatous. Polypectomy was done for all patients, and no massive bleeding, bacterial infection, or perforation were observed. Only five patients had slight bleeding which was treated by conservative measures.}, Keywords = {}, volume = {6}, Number = {1}, pages = {13-15}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1499-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1499-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {AYATOLLAHI, S.M.TAGHI and CARPENTER, RG}, title = {A STUDY OF ADULT HEIGHT, WEIGHT, AND OBESITY IN SHIRAZ, IRAN, 1988-1989.}, abstract ={Height, weight and body mass index (BMI) of married adults aged 20-69 years with a school-aged child in Shiraz (Iran) are reported. Smoothed centile values have been derived from the raw data by Healy's nonparametric method. Factors affecting obesity of adults are examined. Shiraz adults are taller and heavier than most adults from developing areas of the world, but are shorter and lighter than most European countries. They are substantially bigger than previously reported. The results provide normal ranges of height, weight and body mass index (BMI) appropriate for clinical work in Iran.}, Keywords = {}, volume = {6}, Number = {1}, pages = {7-12}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1498-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1498-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} } @article{ author = {AZAR, MAZIAR and TAHAMY, AHMAD and KABOLY, AFSOUN}, title = {MODIFIED METHYLMETHACRYLATE CRANIOPLASTY IN 127 CASES OFWAR CASUALTIES}, abstract ={We report 127 cases who have had elective operation on cranium because of skull bone defect during 1984-1989. Usually repair of skull bone defect and preserving normal anatomy were the major therapeutic goals. 10, II In these cases a new surgical technique is described which can successfully accomplish these goals in a single but staged operative procedure.}, Keywords = {}, volume = {6}, Number = {1}, pages = {1-6}, publisher = {Iran University of Medical Sciences}, url = {http://mjiri.iums.ac.ir/article-1-1497-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1497-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1992} }