@article{ author = {Moshfegh, AA and AZARIPOUR, A and MOTTAGHIAN, H and HAKIMELAHI, GH}, title = {THE SYNTHESIS AND ANTIMICROBIAL PROPERTIES OF 4-CHLORO-2,6-BIS (2-HYDROXY- α- TOLYL) PHENOL}, abstract ={The synthesis of the title compound is described. This compound was found to be active (3c) against a number of pathogenic microorganisms in vitro. It is a non-absorbable antibacterial topically and its pharmacologic studies revealed that it is a non-toxic agent with a wide range of safety. It proved to be effective in the prevention and treatment of pseudomonaswound infections in volunteer patients.}, Keywords = {}, volume = {4}, Number = {4}, pages = {299-300}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1538-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1538-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {RAHIMIAN, ROSHANAK and FARZAMI, BIJAN and SAMADI, ABBAS}, title = {THE ISOLATION OF ENZYME TRANSKETOLASE FROM HUMAN ERYTHROCYTES: THE CHARACTERIZATION OF ITS QUARTERNARY STRUCTURE}, abstract ={Human erythrocyte transketolase (sedoheptulose-7-phosphate: D-glyceraldehyde-3-phosphate, glycolaldehyde transferase, E.C. 2.2.1.1.) has been isolated from erythrocytes with a specific activity of 59.84 U/mg. SDS-PAGE and SE-HPLC were used both as a measure of purity and as a preparative mean to obtain a higher degree of purity. Four protein bands corresponding to molecular weights of 32,000, 39,000, 43,000 and 60,000 were obtained in electrophoresis and SE-HPLC preparations. Activity measurements on the two fractions obtained from SE-HPLC that contained a monomer with the molecular weight of 32,000 and a dimeric fraction with the molecular weight of 60,000 showed that the monomeric form of the enzyme displays activity in the presence and absence of the TPP and Mg(II). This activity was measured to be 14.76 U/mg in the absence of TPP and Mg(II), and 40.24 U/mg in the presence of the cofactors. The dimeric form showed an activity of 58.84 U/mg in the presence of the cofactors.}, Keywords = {}, volume = {4}, Number = {4}, pages = {293-297}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1537-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1537-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {ANAND, KESHAV and PANDE, SAROJ and GUPTA, RK}, title = {CORRELATION BETWEEN ELECTROCARDIOGRAPHIC AND HISTOPATHOLOGICAL CHANGES IN ISOPRENALINE-INDUCED MYOCARDIAL INJURY}, abstract ={Myocardial injury was induced in 25 dogs by infusing isoprenaline, 2-4 microgram per kg per minute for the duration of six hours. 10 dogs served as controls which received only physiological saline. Animals receiving isoprenaline 2 microgram per kg per minute were labelled as experimental group A and other receiving microgram per kg per minute as experimental group B. Histopathological observations in experimental groups A & B showed subendocardial haemorrhage in the papillary muscles and apex of left ventricle as early as two-three hours of infusion. Focal lesions characterized by congestion, dilatation and extravasation of blood was observed near necrotic myocardium. Group A animals showed only severe tachycardia while in group B myocardial infarction in 80% and only ischaemic changes in 20% of animals were observed. Out of animals in group B, 37.5% developed myocardial infarction after two hours of infusion while remaining 62.5% developed changes after four hours. Histopathological changes were very well correlated with ECG findings observed in the present study.}, Keywords = {}, volume = {4}, Number = {4}, pages = {287-291}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1536-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1536-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {TADJBAKHSH, HASSAN}, title = {A SURVEY OF THE VIEWS OF IRANIAN SA V ANTS (ESPECIALLY PERSIAN MUSLIM PHYSICIANS) ON THE SUBJECT OF CONTAGIOUS DISEASES AND IMMUNITY}, abstract ={}, Keywords = {}, volume = {4}, Number = {4}, pages = {273-286}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1535-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1535-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {AYATOLLAHI, S.M.TAGHI and CARPENTER, RG}, title = {GROWTH MODELLING OF SCHOOL CHILDREN IN IRAN USING SHIRAZ DATA}, abstract ={Centile values and growth charts for height, weight and arm circumference are presented for school children aged six to 12 years in Shiraz (Iran). The smooth centile values have been derived from the raw data by Healy's nonparametric method. Girls grow faster than boys. Homogeneity of data with population structure and universal rationing imply that these norms are likely to be appropriate to all urban children in Iran. These observations are in favour of using local standards in clinical diagnosis and nutritional screening in order to develop efficient and effective health programmes.}, Keywords = {}, volume = {4}, Number = {4}, pages = {267-272}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1534-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1534-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {Emami, AR and SAMSAMSHARIAT, Z and SUZANGAR, M and GHANNADI, F and AZIZ-ZADEH, A}, title = {SERUM ZINC CONCENTRATIONS IN DIABETIC PATIENTS COMPARED WITH NON- DIABETICS IN ISFAHAN}, abstract ={To study the zinc concentration differential in diabetic patients compared with non-diabetics and borderline subjects in a sample of two hundred individuals under investigation, we gathered information on history and duration of diabetes as well as type of treatment and diet. In addition, capillary blood glucose and serum zinc concentrations were measured.The serum zinc level was higher in diabetic patients compared to borderline and non-diabetics. The higher level of zinc in diabetic patients may be due to their change of energy source and the lower phytate and higher zinc content of their new diets which consequently reduce the effect of this substance on zinc absorption. The reason for lower levels of zinc in the borderline subjects is not presently clear and needs further investigation.}, Keywords = {}, volume = {4}, Number = {4}, pages = {265-266}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1532-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1532-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {AZARM, TALEB and GHANNADI, FAZLOLLAH}, title = {EFFECTIVENESS OF CHEMOTHERAPY IN 54 CASES OF ADVANCED GASTRIC CANCER IN ISFAHAN}, abstract ={To determine the effectiveness of chemotherapy in the treatment of gastric cancer, a sample of 54 patients suffering from advanced adenocarcinomas were studied. The results of the study showed that the disease is more prevalent in the age group of56-60 years. The three major signs of this kind of cancer were almost equally present among both sexes in our patients. After chemotherapy, 74% of the patients survived up to one year and 50% survived up to two years or more following treatment. Chemotherapy increased the survival rate of the patients but our results were less successful compared to that of other institutions. This probably is due to delayed referral of patients to the physician. It is suggested that those patients in age groups 56-60 showing the slightest signs of gastric cancer be examined by a physician and it is hoped that early detection of the disease will increase the survival rate of the patients.}, Keywords = {}, volume = {4}, Number = {4}, pages = {261-264}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1531-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1531-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {ZANDIEH, T and MARZBAN, S and HASSIRI, G and TARABADI, F and ANSARI, H}, title = {EVALUATION OF CELL-MEDIATED IMMUNITY IN MUSTARD GAS INJURIES}, abstract ={Yamakido, et al. in 1986 have studied immunological parameters in poison gas workers, and a depression has been observed in immunologic response. Also, the frequency of cancer has reached as high as five-fold that of the general population. In the present study, cell-mediated immunity (CMI) was measured in three groups of Iranian mustard gas-injured patients. The first group were those who had been injured three months up to one year before, and the second group were studied one to two years after in jury, and the third. group were studied after two years from the time of injury. The following results were obtained: 1- In comparison with normal controls (61.5±4), T lymphocytes showed a significant decrease in 50% of the three groups (50.71±15. 7 46.95±15) of poison gas injury, and B lymphocytes were increased, but no significant difference could be seen in mitogen response to PHA. 2- In comparison with normal control (47 ±9), T helpercells (T4) in 52% of the first and second groups were significantly decreased (33. 14± 16.59). 3- T suppressor cells (T8) in 53% of the first group, and in 22% of the second and third groups (27.29±11. 77 21. 4±6. 89) were increased in comparison with normal controls (20±6). 4- Ratio of T4 to T8 in 71 010" of the first group and 60% of the second and third groups were decreased. Therefore depression of CMI in poison gas injury was observed after one, two, and three years, which will be discussed in this paper.}, Keywords = {}, volume = {4}, Number = {4}, pages = {257-260}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1530-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1530-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {ILBEIGI, MS}, title = {URETEROSCOPY IN 104 PATIENTS}, abstract ={From July, 1987 to Oct, 1989 , 104 patients underwent 111 transurethral ureteroscopy procedures at the Air Force Medical Center. All intramural ureters were dilated by flexible metal dilators. The overall success rate for ureteral stone removal was 95.8 per cent. Ureteroscopy was done for evaluation of gross hematuria, strictures, ureteral stent, and ureteral and pyelocalyceal tumors. The overall mean hospital stay was 2.5 days with no important complications.}, Keywords = {}, volume = {4}, Number = {4}, pages = {253-255}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1529-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1529-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {BASIRI, ABBAS and SIMFOROOSH, NASSER}, title = {TRANS URETERAL LITHOTRIPSY}, abstract ={From Sep. 1984 to Aug. 1990,99 patients were treated for ureteral stone using the urekroscope. In five patients ureteroscopy was repeated for a second stone. In one patient the procedure was diagnostic in nature and in the rest of the patients it had a curative value. In 60 patients the stone was removed by electrohydraulic and basket combination and in25 cases, dilatation alone was enough. Rate of success was 84.6%, with a 10% rate of complications. We conclude that TU L is the treatment of choice for ESWL- resistant stones or in patients with ureteral anomalies.}, Keywords = {}, volume = {4}, Number = {4}, pages = {247-252}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1528-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1528-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {KALANTARMOTAMEDI, MOHAMMADREZA}, title = {VASCULAR ACCESS FOR HEMODIALYSIS: OUR EXPERIENCE WITH 3337 CASES}, abstract ={Over a seven year period from 1982 to 1989,3337 conduits were created in 3137 patients with end stage renal disease (ESRD) as access for chronic dialysis. These included 2690 side-to-side arteriovenous fistulae (A VF), 168 end-to-side A VFs, 10 autogenous vein grafts, 51 homogenous frozen vein grafts, 109 polytetrafluoroethylene (PTFE) grafts, 209 emergency external arteriovenous shunts, three dual-lumen catheter placements with dacron felt cuff in the superior vena cava and 13 miscellaneous vascular access procedures. Our favorite site for creation of A VFs along with satisfactory patency rates for as long as seven years are demonstrated for all types of fistulae and PTFE grafts by life-table analysis. Early failure of A VFs usually occurred in the postoperative period due to hypotension, and late failures were due to improper use of the vein during dialysis. Thrombosis was the cause of the majority of the PTFE graft failures, even though we had four cases of infection more than one year later and one case of seroma formation due to weeping of the graft. False aneurysm formation and secondary bleeding requiring repair were the major complications of PTFE grafts. Autogenous or frozen banked homogenous vein graft failures were mainly due to gradual fibrosis and narrowing and eventual thrombosis, while we did not have infection or false aneurysm formation or any other complication with them.}, Keywords = {}, volume = {4}, Number = {4}, pages = {241-246}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1527-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1527-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MOHAMMAD, KAZEM and M.M.FARAHANI, MAHMOOD}, title = {ESTIMATING INFANT AND CHILD MORTALITY IN IRAN, 1989}, abstract ={This paper presents estimates of infant and child mortality in the rural and urban areas of Iran for 1989. Data are from a one percent sample of the urban and rural population. The study makes use of data on the number of children born alive and children surviving, classified by age of the mother. Based on these data estimates of infant and child mortality for the urban and the rural areas have been calculated separately by using the Trussell version of the Brass method. The results of this study show that the infant mortality rates in the rural and urban areas of Iran are 70 and 35 per thousand, respectively. The estimates obtained from previous retrospective studies are compared with the current rates. Datails of the method, limitations of the data and discussion of the results are given in the paper.}, Keywords = {}, volume = {4}, Number = {3}, pages = {215-218}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1549-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1549-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {SOHRABI, FEREYDOUN and FARZAN, ALI}, title = {A COMPARATIVE STUDY OF URBAN AND RURAL TETANUS IN ADULTS}, abstract ={An analysis of 382 patients, aged 12 and over, admitted to the infectious disease ward of Amin Hospital in Isfahan over a 20 year period with clinically diagnosed tetanus is reported. The study comprised 297 patients, 77.7% from rural areas and 85(22.3%) from the city of Isfahan. The male- female ratio for both groups was approximately 2:1. Rural patients were younger and showed a lower crude case fatality rate. Traditional practices such as application of cow manure to the wounds, and unhygienic circumcision and ear piercing were important contributing factors in developing tetanus, demonstrating a need for health education in rural communities.}, Keywords = {}, volume = {4}, Number = {3}, pages = {211-214}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1548-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1548-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {RAJABIAN, R and SHAHBAZI, H and PARIZADEH, J and ABDINEJAD, A and SAYADPOUR, K and ABDOSSALAMI, H}, title = {IODINE DEFICIENCY DISORDERS IN NEISHABOUR}, abstract ={Iodine deficiency has been considered in Iran since 20 years ago and has been acknowledged recently. We studied iodine deficiency disorders in 1618 Neishabourian students. 60% of children had palpable and 2.5% had visible goiters. Height and weight of these children were lower than International and Tehranian children but higher than Isfahanian children. Hormone studies showed increased T4, decreased T3RU, increased T3 and T31T4 ratio which are indicators of iodine deficiency.}, Keywords = {}, volume = {4}, Number = {3}, pages = {207-210}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1547-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1547-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {DJERIC, DRAGOSLAVA R. and SAYIC, DRAGOSLAV LJ.}, title = {PROPOSAL FOR SURGICAL CLASSIFICATION OF CHRONIC SUPPURATIVE OTITIS MEDIA}, abstract ={The authors presented a proposal for surgical classification of chronic suppurative otitis media which may be used' for evaluating the surgical outcome of the disease.}, Keywords = {}, volume = {4}, Number = {3}, pages = {201-202}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1546-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1546-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {REZAEIPOUR, ROBABEH and BUNGYPOUR, GHOLAM ALI}, title = {CHARACTERIZATION OF IMMUNE RESPONSE TO MUSTARD GAS USING A NEW FLUOROIMMUNOASSAY}, abstract ={One way to confront chemical warfare in order to reduce their harmful effects, is to use the body's defense mechanisms. In order to do so firstly mustard gas (HD) was injected in an animal model in the form of an immunogen and the induced humoral immune response was investigated by two different immunological methods such as the Ouchterlony test and a new liquid phase fluoroimmunoassay. 7lt was proved that the animal model had produced specific antibodies against mustard gas which could specifically interact with the chemical gas.}, Keywords = {}, volume = {4}, Number = {3}, pages = {197-200}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1545-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1545-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {AZIZI, F and ELYASI, H and JALALI, N and NAFARABAD, M}, title = {TRANSIENT DECREASED SERUM TESTOSTERONE AFTER EXPOSURE TO MUSTARD GAS}, abstract ={The effects of exposure to chemical weapons containing sulfur mustards on the serum levels of total and free testosterone. gonadotropins and prolactin was investigated in young Iranian men. In the first five weeks after injury both serum total and free testosterone were significantly decreased as compared to control values. Three of 13 men had total testosterone below 300 ng/dL and two of six had subnormal serum free testosterone concentra• tions. By the fifth week after exposure serum free testosterone did not change however there was further fall in mean serum total testosterone ancI 70% of men had subnormal values. Both serum total and free testosterone concentrations returned to normal values by the 12th week after injury. There was a significant rise in serum FSH and prolactin by the fifth week ancI in serum LH by the fourth week after exposure. These data suggest that injury by the chemical warfare containing sulfur mustard may cause acute inhibition of testosterone secretion from the testis leading to a significant decline in serum total and free testosterone and some increase in gonadotropin concentrations. The inhibition seems to be transient ancI hormone levels return to normal by 12th week after injury.}, Keywords = {}, volume = {4}, Number = {3}, pages = {191-195}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1544-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1544-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {TABARESTANI, M and BALAU-MOOD, M and FARHOODI, M}, title = {HEMATOLOGICAL FINDINGS OF SULPHUR MUSTARD POISONING IN IRANIAN COMBATANTS}, abstract ={Sulphur mustard (SM) is an alkylating agent that was first used as a chemical warfare agent during the First World War in 1917. SM is readily absorbed from the skin, respiratory and gastrointestinal tract and is distributed to several organs. SM may act rapidly and persistently upon DNA replicating mechanism of the individual cells during mitosis particularly in the hematopoietic system. Of 233 patients with SM poisoning, hematological investigations were performed in 213 of them. Mild changes were observed in red blood cells and its indices. Initial leukocytosis (> llxl09/L) was observed in 7.2% and leucopenia (‹4x 109/L) in 3.8% of the patients. Marked lymphopenia, neutrocytosis and eosinopenia (‹2%) were found in 36%,38%, and 25% of the patients, respectively. Bone marrow biopsy in 3 fatal cases revealed marked hypocellularity and dyserythropoietic changes. Apart from the respiratory complications, mortality from SM poisoning is mainly due to bone marrow failure.}, Keywords = {}, volume = {4}, Number = {3}, pages = {185-190}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1543-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1543-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {SAREMI, FARHOOD}, title = {PERCUTANEOUS DRAINAGE OF ABDOMINAL ABSCESSES AND FLUID COLLECTIONS}, abstract ={This report summarizes the results of 64 percutaneous catheter drainage of abdominal abscesses and fluid collections in 56 patients. Aspiration and drainage was guided with computed tomography in 34 patients and with ultrasound in 30 patients. Success rate was 90%. Infected collections were successfully drained in 94% and noninfected collections in 72% . Partial success was achieved in two patients. Three patients failed to respond to percutaneous drainage. Recurrence occurred in one. Complications occurred in nine patients, two of which were major (3%) and seven were minor ( 1 1 %). Image- guided percutaneous drainage appears to be the treatment of choice for most of the intraabdominal collections.}, Keywords = {}, volume = {4}, Number = {3}, pages = {177-184}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1542-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1542-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {GHARIB, HOSSEIN}, title = {THYROID FOLLICULAR ADENOMA: BENIGN OR MALIGNANT?}, abstract ={Four patients are described in whom a follicular carcinoma developed following thyroidectomy for a benign follicular neoplasm. It is possible that the initial thyroid neoplasm was a well- differentiated follicular carcinoma which was microscopically indistinguishable from a benign adenoma. Realizing this pathologic pitfall in thyroid diagnosis, the need for meticulous examination of the pathologic specimen is emphasized. Long- term postoperative reassessment is recommended.}, Keywords = {}, volume = {4}, Number = {3}, pages = {173-176}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1541-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1541-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {FAZEL, lRADJ}, title = {MASSIVE GASTROINTESTINAL HEMORRHAGE IN COMBAT CASUALTIES AND TRAUMA VICTIMS SECONDARY TO ARTERIO-VISCERAL FISTULAS}, abstract ={Massive upper gastrointestinal bleeding is a known complication of advanced sepsis in trauma patients and carries a grave prognosis. However, to our knowledge, an important cause of massive gastrointestinal bleeding, arterio-visceral fistula, has not been discussed in the literature. The most common cause of this unique clinical entity is penetrating high velocity abdominal injuries, although blunt trauma may also be responsible. Due to partial injury of the major intraabdominal vessels, a false aneurysm is formed. The intraabdominal false aneurysm, causing pressure necrosis in the intestinal wall, perforates into the gut with massive hemorrhage. Characteristics of this hemorrhage include its massive and bright red nature, recurrence, and curability with correct diagnosis and appropriate treatment. Our experience with sixteen cases, clinical presentation, diagnostic features and surgical treatment is discussed in this paper.}, Keywords = {}, volume = {4}, Number = {3}, pages = {165-172}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1540-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1540-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MOKHTARIAMIRMAJDI, NEMATOLLAH and SHARIFI, MASSOUD}, title = {HEARING IMPAIRMENT CAUSED BY WAR}, abstract ={120 cases of Iranian soldiers complaining of hearing loss, were studied over a period of three years at the Ghaem Medical Center in Mashad,Iran. There was adequate information in III cases that their engagement in different types of explosions had caused their hearing impairment. The following aspects were evaluated: 1- Categorization of their hearing impairment. 2- The otoscopic findings. 3- The severity of the hearing impairment, the side of involvement and their relation to the type of explosion. This study while implying that war seems to be a major factor in causing hearing impairment, intends to clarify some of the cause and effect relations also. The hearing impairment caused by war can be of different types and severity and will be a real handicap. The abrupt loud impact noise and blast wave exposure are considered to be causes of hearing impairment. In ourseriesof III cases the different types of sensorineural hearing loss are more common than simple ruptured ear-drums.}, Keywords = {}, volume = {4}, Number = {3}, pages = {161-163}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1539-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1539-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {BIGDELI, MG and DABIRASHRAFI, H and MOGHEISI, F and MOGHADAMITABRIZI, N}, title = {SERUM 6-hCG CONCENTRATION CHANGES FOLLOWING INTRAMUSCULAR hCG ADMINISTRATION}, abstract ={In circumstances such as in vitro fertilization (IVF) or in patients with luteal phase defect, one needs to ensure the establishment of pregnancy as soon as possible. At the same time, a question arises: How can a physician make sure that the β-hCG is of an endogenous source and not the residue of the prescribed drugs (hCG)? In this article we have studied the elimination time of 1M injection of 5000 IU hCG in 11 normal, and 1M injection of 5000 and 10,000 IU hCG in 11 Rokitansky patients. The time of complete elimination of β-hCG from the circulation in 10 normal women and 5 Rokitansky patients receiving 5000 IU of hCG were 7-11, and 7-8 days respectively. There was no statistically significant difference between these two groups. Comparing the two groups of Rokitansky patients receiving 5,000 and 10,000 IV of hCG, the elimination time were dose-dependent, and were significantly different from each other (P<0.01). We conclude that when the serum level of β-hCG is higher than 5m IU/ml after 11 and 14 days with 5,000 and 10,000 IV of hCG injection, it could be accepted as an implanted pregnancy.}, Keywords = {}, volume = {4}, Number = {2}, pages = {133-135}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1561-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1561-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {VESSAL, M and AKMALI, M}, title = {ENZYME LEVELS IN THE SERA AND ERYTHROCYTES OF PATIENTS WITH VISCERAL LEISH MANIASIS}, abstract ={Twenty five blood samples from 6-month to 5-year old children with visceral leishmaniasis were analysed for various enzymes. Aspartate transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LD) and its various isoenzymes were estimated in the serum, while glucose 6-phosphate dehydrogenase (G6PD) was measured in red blood cells. For comparison, blood samples from healthy children of the same age group (controls) were analysed in similar manner. Significantly higher values were obtained for the activities and the specific activities of AST, AL T and total LD in the patients. The activity and the percentage of LD-5 isoenzyme of the kala-azar patients were also significantly higher than the controls, while the percentage of LD-1 isoenzyme was significantly decreased. Hematocrit levels and G6PD activities of the visceral leishmaniasis patients were also significantly diminished.}, Keywords = {}, volume = {4}, Number = {2}, pages = {129-131}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1560-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1560-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MAKVANDI, ME and DIGHE, PY and KALANTARI, H}, title = {STUDIES ON HEPATITIS B VACCINES}, abstract ={HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Green Cross Corporation, Osaka, Japan). We conclude that vaccine prepared by PEG-6000 precipitation gives better results.}, Keywords = {}, volume = {4}, Number = {2}, pages = {125-128}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1559-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1559-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MOSHTAGHIE, ALI ASGHAR and ANI, MOHSEN and AZANI, MEHDI and SHEIKHZEINODINI, MOHAMAD}, title = {COMPREHENSIVE STUDY OF SOME PLASMA BIOCHEMICAL PARAMETERS IN RELATIONTO BONE DISEASE IN HEMODIALYSIS PATIENTS IN ISFAHAN}, abstract ={The concentrations of serum calcitonin', parathormone (PTH), amylase, alkaline phosphatase (ALKP), calcium and phosphorus were studied in pre-and post-dialysis patients with chronic renal failure. All patients had extremely elevated serum urea and creatinine concentrations with the mean values of143.8 and 10.5 mg/dL respectively. The plasma amylase activity was higher than normal with a mean of 174 lUlL, but showed no significant changes following hemodialysis. The mean values for calcium and phosphorus in pre dialysis plasma were 7.2 and 7.5 mg/dL respectively, whereas it changed to 8.6 and 3.8 mgldL post-dialysis. The extent of increase in PTH and alkaline phosphatase levels depended on the duration of dialysis in the majority of the patients. The longer the period of the dialysis, the higher the concentrations of PTH and ALKP. On the basis of this study the relationship between bone disease and hemodialysis has been discussed.}, Keywords = {}, volume = {4}, Number = {2}, pages = {121-124}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1558-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1558-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {GOLIAEI, BAHRAM and SCHOOLEY, JOHN C.}, title = {SEQUESTRATION OF LEUKOCYTES BY THE ISOLATED PERFUSED RAT LUNG}, abstract ={The sequestration of rat leukocytes and bone marrow cells by the lung vasculature was studied using an isolated perfused rat lung preparation. The passage of latex particles of 7.6 µm in diameter and non-hematopoietic cells through the lung blood vessels was also studied. Leukocytes and bone marrow cells were reversibly sequestered from circulation, whereas, latex particles and non-hematopoietic cells were removed irreversibly. Continuous circulation of leukocytes or bone marrow cells results in a steady state at which circulating cells and the lung reach some kind of equilibrium wi th no net cell removal by the lung. Further cell removal or release can occur by changing the circulating cell concentration. Removal of Ca++ and Mg++ from circulating medium decreased the sequestration of leukocytes by the lung. Complement activation is not involved in this process, since whole blood as well as serum free suspension of leukocytes, bone marrow cells or peritoneal cavity neutrophils showed similar patterns of sequestration. The results indicate that cell sequestration by the isolated perfused lung is a physiological process which can be considered as a suitable model of the in-vivo sequestration of blood leukocytes by the vascular system of the body. The pattern and the rate of sequestration depends on the cell type, cell concentration in circulation, and chemical factors in circulating medium. The results provide new information about the mechanisms which might be responsible for the sequestration of leukocytes by the lung vasculature in the absence of complement activation}, Keywords = {}, volume = {4}, Number = {2}, pages = {113-120}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1557-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1557-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {FARHADI, M}, title = {IBN SINA\'S VIEWS CONCERNING THE RECURRENT LARYNGEAL NERVE}, abstract ={}, Keywords = {}, volume = {4}, Number = {2}, pages = {109-111}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1556-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1556-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {AZIZI, F and AMID, MH}, title = {CLINICAL PRESENTATION OF CHEMICAL WARFARE INJURIES IN CHILDREN AND TEENAGERS}, abstract ={Clinical manifestations of sixteen children and teenagers exposed to chemical warfare in Halabje are presented. 15 patients complained of burning of skin. Dry coughing was present in 13 subjects. The most frequent signs were conjunctivitis, skin erythema, edema of the eyelids, hyperpigmentation, ulceration, erosion, dyspnea, closure ofthe eyes, blisters, edema of the skin, and crepitation in both lungs, in decreasing order of frequency. Two subjects had severe fatal leukopenia and anemia and three showed a transient leukopenia. Four of six teen died of bone marrow hypoplasia, sepsis and respiratory distress. This report again reminds need for an urgent international agreement to effectively ban the use of chemical weapons.}, Keywords = {}, volume = {4}, Number = {2}, pages = {103-108}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1555-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1555-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {SHAMSA, A}, title = {RENAL INJURIES IN MASHHAD UNIVERSITY DURING THE IRAN-IRAQ WAR. A COMPARISON WITH WORLD WARS I AND II, AND VIETNAM}, abstract ={Missile injuries of the kidney are rare even in wartime. Of 4500 patients admitted to the Ghaem Medical Center in the first two years of the Iran-Iraq war, only 96 had injuries of the genitourinary tract (2.1 %) and only 35 involved the kidney usually with multiple injuries to other viscera. The mortality for those with urogenital injuries was 8.3% (compared with World War I, 60% and World War II, 8.3%). The advantage of early helicopter evacuation and prompt forward surgery is once more emphasized. The mean time between wounding and surgery was 48 minutes in this series (compared with 60 minutes in Vietnam and 16 hours in World War II).}, Keywords = {}, volume = {4}, Number = {2}, pages = {97-101}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1554-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1554-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {TOOSI, P and GHALAMKARPOUR, F}, title = {SCROTAL TONGUE ASA VALUABLE CLINICAL FEATURE IN PSORIASIS}, abstract ={In a prospective clinical trial, the incidence of scrotal tongue in psoriatic patients was studied. One hundred psoriatics and the same number of non-psoriatic individuals were evaluated for the incidence of fissured tongue, age, duration of illness, and clinical types of psoriasis. In this study 49 psoriatic patients (49%) and 28 non-psoriatic persons (28%) had fissured tongue. The most common type of psoriasis (38% of patients) was plaque type and the patients'mean age was 22 years. We conclude that scrotal tongue had a higher incidence among psoriatic patients and can be considered as a useful clinical sign.}, Keywords = {}, volume = {4}, Number = {2}, pages = {93-95}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1553-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1553-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {VAHEDI, PARVIZ}, title = {THE DIAGNOSTIC YIELD OF TRANSBRONCHIAL LUNG BIOPSY IN DIFFUSE INFILTRATIVE PULMONARY DISEASES BY PLAIN CUP FORCEPS. A STUDY OF 54 CASES IN IRAN}, abstract ={The technique of transbronchial lung biopsy (TBLB) has expanded the diagnostic yield of bronchoscopy . In this article we are presenting 54 patients with diffuse pulmonary parenchymal involvement who underwent this procedure during six years between June 1980 and December 1989. The diagnostic yield of this technique in diffuse pulmonary parenchymal disease is great and was 66 percent excluding nonspecific pulmonary fibrosis. Compared with other literature this is a good way of diagnosing interstitial lung disease which obviates the need for transcutaneous lung biopsy and thoracotomy.}, Keywords = {}, volume = {4}, Number = {2}, pages = {87-91}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1552-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1552-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {AREFI, HASSAN and KAMAL-HEDAYAT, DARIUSH}, title = {C-REACTIVE PROTEIN RESPONSE IN ANGINA PECTORIS}, abstract ={C-reactive protein (CRP) response was studied in 44 patients with acute angina pectoris admitted to the coronary care unit. 71 % of patients with acute myocardial infarction (MI)had positive CRP test while 73% of patients presumed to have unstable angina pectoris had negative CRP test. This test can be helpful in differentiating between acute MI and unstable angina pectoris.}, Keywords = {}, volume = {4}, Number = {2}, pages = {85-86}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1551-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1551-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {VELAYATI, ALI AKBAR and FARHOUDI, ABOL HASSAN and BAHRAMI, MANSOUR}, title = {A CLINICAL AND IMMUNOLOGICAL COMPARATIVE STUDY ON 522 BREAST-FED CHILDREN}, abstract ={Until now, there have been various studies concerning bottle-fed and breast-fed children. Prevalence of allergic manifestations like eczema and asthma among bottle-fed children is much higher than healthy controls. In this study, we found that respiratory infection for breast-fed children was 3.1%, whereas in bottle-fed children it was 25.1%for gut disorders, 9.2% in breast-fed vs.13.1 % for bottle-fed children eczema 22.9% in breast fed and 33.3% in bottle-fed children while asthma was 14.5% in breast-fed and 26% in bottle-fed children. We conclude that prevalence of respiratory, allergic and GI tract infections are much higher in bottle-fed infants than in breast-fed ones. This is somewhat in contradiction to that of American and European reports.}, Keywords = {}, volume = {4}, Number = {2}, pages = {81-83}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1550-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1550-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {SAMADI, ABBAS K. and MALEKNIA, NASSER}, title = {SEPARATION OF NONHISTONE HIGH MOBILITY GROUP (HMG) FROM HUMAN LYMPHOCYTES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY}, abstract ={The high mobility group (HMG) of nonhistone proteins have been investigated using two high performance liquid chromatographic techniques (HPLC). Reversed-phase HPLC under conditions of 50 mM triethylamine adjusted to pH 2.2 with phosphoric acid (solvent A) and 95% acetonitrile in water (solvent B) was used to separate proteins primarily on the basis of differences in the overall hydrophobicity. Size exclusion HPLC under conditions of two different solvents (A, 0.1 % trifluoroacetic acid 1FA B, 1.0% sodium dodecyl sulphate, SDS) was used to separate proteins. HMG proteins from human lymphocytes were separated into the HMG 1, HMG 2, HMG 14 and HMG 17 components. RP-HPLC is a proper method to resolve all the human lymphocyte HMG-proteins. Size exclusion HPLC was employed to resolve the HMG-protein subunits and determine their molecular weights. Ideal SE-HPLC is not capable of resolving HMG 1 from HMG 2 or HMG 14 from HM G 17 due to their molecular weight similarities. The purity of protein fractions were examined by acetic acid-urea-triton X-100 gel electrophoresis.}, Keywords = {}, volume = {4}, Number = {1}, pages = {65-70}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1573-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1573-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {NOURMOHAMMADI, ISSA and HONARI, ZOHREH and KESHAVARZ, ALI and NILFORUSHAN, MOSTAFA}, title = {PLASMA DEHYDROASCORBIC ACID LEVELS IN IRANIAN SUBJECTS WITH DIABETES MELLITUS}, abstract ={Several reports concerning high plasma dehydroascorbic acid (DHAsA) levels in diabetics have been published and from these reports, suggestions that monitoring of DHAsA levels in those persons with a predisposition to diabetes mellitus would be of value. However, conflicting reports have also appeared which do not confirm high levels of DHAsA in diabetic subjects when compared to controls. Because of these conflicting results, this investigation using Iranian diabetic subjects was undertaken to ascertain whether or not periodic monitoring of DHAsA levels would be of value as an indicator of prediabetic conditions. Our results do not confirm high levels of DHAsA in diabetics but because of the many theories concerning the mechanism of action and the metabolism of DHAsA, previous findings cannot be disregarded.}, Keywords = {}, volume = {4}, Number = {1}, pages = {61-64}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1572-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1572-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {A. NAJAFI-FARASHAH, A}, title = {ENDOGENOUS RELEASE OF OPIATES BY REPETITIVE ELECTRICAL FIELD STIMULATION IN THE GUINEA-PIG AND RAT ILEAL LONGITUDINAL MUSCLE}, abstract ={The effect of repetitive electrical field stimulation and the response of the guinea-pig and rat ileal longitudinal muscle to single pulse stimulations was examined. Single pulse field stimulation produced twitch contraction which was inhibited by repetitive field stimulation (10 Hz, 40V, 0.5 msec for 5 m). This inhibition was largely, though never completely, reversed by naloxone. Contractions due to exogenous acetylcholine and histamine were also inhibited after repetitive field stimulation. The inhibition of acetylcholine response was party reversed by naloxone whereas that of histamine was not. Contractions due to single pulse field stimulation or to either acetylcholine or histamine were inhibited by prior exposure to high concentrations of acetylcholine as a substitute for high frequency stimulation. The inhibitory responses were resistant to naloxone. The inhibitory responses to acetylcholine and histamine after exposure to the lowest concentration of acetylcholine was seen in preparations treated with tetrodotoxin or hemicholinium. The inhibition of the histamine response by acetylcholine pretreatment was prevented by mepyramine. Response to histamine, but not those to single pulse field stimulation or acetylcholine, were inhibited by prior exposure to histamine. It is concluded that repetitive field stimulation possibly initiates two distinct inhibitory processes. One involves the release of endogenous opiates and is probably mediated by inhibition of acetylcholine release. The second type of inhibition is not mediated by endogenous opiates and can be explained by post-junctional desensitization. The non-specific desensitization to histamine is probably a consequence of histamine release from mast cells by acetylcholine.}, Keywords = {}, volume = {4}, Number = {1}, pages = {53-59}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1571-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1571-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {NOBAKHT, M and SIMFOROOSH, N and MOHAMADIAN, ALI and AMIR-ANSARI, B}, title = {THE ROLE OF T-L YMPHOCYTE SUBPOPULATION IN RENAL ALLOGRAFT REJECTION}, abstract ={Twenty-two recipients of HLA-nonidentical living related and nonrelated renal allografts were studied for alterations in the relative percentage of OKT4-positive peripheral blood T-cells after transplantation. Characteristic shifts in the ratio of T-helper to T -suppressor/cytotoxic cells (TH/TS-C), but not absolute cell numbers, were demonstrated to correspond with the status of the allograft. Our results are indicative of a correlation between rejection episodes and the increase in OKT4:0KT8 ratios, that were characterized by a significant rise in the percentage of OKT4-positive cells (P=0.001), and a decrease in the percentage of OKT8-positive cells (P=0.001).}, Keywords = {}, volume = {4}, Number = {1}, pages = {47-52}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1570-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1570-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MOHARRERI, MR}, title = {NEUROPSYCHIATRIC DISORDERS IN THE OLDEST MEDICAL TEXTBOOK IN PERSIAN WRITTEN AROUND 990 A.D.}, abstract ={Written around 990 A.D., Hidayat-MllIaallemill Fit Tibb (Student's Guide ill Medicine) is the oldest general medical text known to have been written in modern Persian. Little is known of the author other than the fact that he was apparently a well experienced practicing physician by the name of Abu Bah Rabi' bin Ahmad al-Akhawaini from Bukhara who claimed to bea second generation student of Razi. The neuropsychiatric sections of the book are of particular interest because the author apparently had a personal interest in and reputation for treating the insane. According to one of the manuscripts he was known as the "Physician of the Insane" by his contemporaries. Following the line of other Islamic medical writers, the author has described the major neuropsychiatric disorders in the chapter dealing with the "Diseases of the Head and Brain". These include Melancholia, Mania, Epilepsy, Phrenitis, Lethargy, and Delerium. Hysteria is, however, described among the diseases of the female reproductive system. Both the terminology used and the authorities quoted betray the author's schooling in and devotion to the Graeco-Roman medical traditions adopted by early Islamic medical writers. He emerges as a hard-headed organic physician dedicated to the humoral doctrines of mental illness.}, Keywords = {}, volume = {4}, Number = {1}, pages = {37-46}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1569-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1569-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {VAHEDI, PARVIZ}, title = {A STUDY OF 17 PATIENTS WITH PULMONARY SARCOIDOSIS IN MASHAD}, abstract ={Thirty patients with bilateral lymph node enlargement with or without parenchymal infiltrates on the chest x- ray suspected to have sarcoidosis were studied between June 1980 and December 1989 in our institution. Eleven of these patients who were free of parenchymal infiltrates did not have a biopsy performed and the diagnosis of sarcoidosis was made based on self-limited regression and clearing of the chest X-ray findings. However, these cases Were excluded from our study along With two other cases which upon transbronchial lung biopsy (TBLB) failed to show the disease. Seventeen of our cases had sarcoidosis, fourteen proven by TBLB, two by skin biopsy and one by parotid gland biopsy. Our study shows that sarcoidosis is not a rare disease in IRAN. TBLB is a good way to diagnose sarcoidosis especially when parenchymal involvement is present on the chest X-ray. Although stage I of the disease was more common in our series, it is probable that this is a false findingimd if TBLB were repeated more cases of stage III of the disease would be found.}, Keywords = {}, volume = {4}, Number = {1}, pages = {31-36}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1568-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1568-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {AMINI, SAFIEH and SOLATI, ALI ASGHAR and FAYAZ, AHMAD and MAHMOODI, MAHMOOD}, title = {ROTAVIRUS INFECTION IN CHILDREN WITH ACUTE DIARRHEA IN TEHRAN}, abstract ={The etiology of acute diarrhea was studied in 915 children under 5 years of age between March 1986 and August 1987, in 7 hospitals in Tehran. 65 healthy children in similar age groups served as controls. Rotavirus was found in 25% of the patients and 1.5% of controls with the highest detection rate occurring in the 7-24 month age group (28%) and declining beyond 25 months of age (5%). The infection rate was also high (19%) in the first 6 months of life and breast feeding was not protective. The rate of rotavirus infection was highest during the months of April and May (30% and 37% respectively) and lowest during December and January (7%).}, Keywords = {}, volume = {4}, Number = {1}, pages = {25-28}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1567-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1567-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MUFTI, TARIQ and SULTAN, SYED and AHMED, R and ALI, G and AZIZI, A and NAWAZ, M}, title = {SIMPLE LIGATION VERSUS STUMP INVAGINATION DURING APPENDICECTOMY-A PROSPECTIVE TRIAL}, abstract ={A prospective, randomized trial on 416 consecutive cases of appendicectomies was carried out in which half of the cases had simple ligation of the stump and the rest had invagination of the stump in addition. The two groups were matched for age, sex, state of personal hygiene and nutrition. The incidence of wound infection, and early and late post-operative complications remained comparable between the two groups. However, the mean operating time was significantly less in case of simple ligation. Barium enema in suspected cases of caecal neoplasm in post-operative cases did not reveal any ceacal deformity in the group of simple ligation thus avoiding confusion of mistaking deformed caecum due to the invaginated stumps as neoplasm. Simple ligation of the appendiceal stump is therefore advocated during appendicectomy.}, Keywords = {}, volume = {4}, Number = {1}, pages = {21-23}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1566-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1566-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {JANGHORBANI, MOHSEN and HEDLEY, ANTHONY J. and JONES, RAYMOND B and GILMOUR, HARPER and ZHIANPOUR, MOTAHAREH and GILLIS, CHARLES R. and HAWTHORNE, VICTOR M.}, title = {BLOOD PRESSURE COMPONENTS AS PREDICTORS OF STROKE MORTALITY IN WEST SCOTLAND}, abstract ={The relative importance of systolic (SBP) versus diastolic blood pressure (DBP) and other combinations of SBP and DBP in the prediction of stroke have been re-examined in a long term cohort study of 10,541 men and women aged 45-64 in West Scotland. During a mean follow-up of 11.6 years 1, 616 deaths occurred, among which 160 (9.9% 80 male, 80 female) were due to stroke. In a multiple logistic regression (MLR) model the predictive values of SBP, DBP, mean arterial pressure (MAP), mean arterial index (MAl) and pulse pressure (PP) were examined in relation to stroke mortality after adjustment for age, body mass index (BMI), casual blood glucose, serum cholesterol, and cigarette smoking at entry. All blood pressure measures were associated with stroke mortality in females the risk of stroke mortality was more strongly associated with DBP in males SSP and DBP have the same predictive influence on stroke mortality and the MAP and MAl have stronger associations with it than either SBP and DBP. PP is associated with the least excess risk in both genders.}, Keywords = {}, volume = {4}, Number = {1}, pages = {13-19}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1565-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1565-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {EMAMI, MASOOD and GHAHRI, MOHAMMAD}, title = {PREVALENCE OF PITYRIASIS VERSICOLOR IN WAR-WOUNDED AND CHEMICAL (MUSTARD) GAS-WOUNDED PATIENTS IN IRAN-IRAQ WAR}, abstract ={A total of 1118 soldiers who were wounded in war and hospitalized in Tehran, were examined for P .versicolor-a superficial mycotic infection. Of these, 213 were war-wounded, 54 chemical (mustard) gas-wounded, 42 both war and chemical gas-wounded, 105 had infectious and noninfectious diseases, and 704 were apparently healthy soldiers serving in war fronts who were examined for P. versicolor and its relation with a history of contact with mustard gas. In this study the prevalence of P. versicolor among the above groups was: 7.40%, 1.85%, 9.52%, 11.42% and 6.11 % respectively. Upon microscopic examination (Scotch tape method) from hyperpigmented parts of the skin resulting from mustard gas, P. orbiculare (the etiologic agent of P. versicolor) was seen abundantly. This observation leads us to hypothesize that there may be a relation between P. versicolor and previous contact with mustard gas.}, Keywords = {}, volume = {4}, Number = {1}, pages = {9-11}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1564-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1564-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {MOGHARI, AHMAD and FOROOTAN, KS and EMAMI, SA}, title = {THE CLINICAL APPLICATION OF PREFABRICATED FREE FLAPS FOR NASAL RECONSTRUCTION}, abstract ={We have found prefabrication of hairless radial forearm free flap to be a useful technique for nasal reconstruction. Prior skin grafting and a suitable period of maturation permits safe, reliable surgery. Its use should be considered in those patients whose forehead tissue is not suitable or in whom appropriate distant flaps are not available, as is often the case with hirsute males.}, Keywords = {}, volume = {4}, Number = {1}, pages = {5-8}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1563-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1563-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} } @article{ author = {VELAYATI, AA and MOHAMMADI, M}, title = {CHILDHOOD RESPIRATORY TUBERCULOSIS IN IRAN}, abstract ={To estimate the bacterio-epidemiological situation of childhood respiratory tuberculosis in Iran, 2185 symptomatic patients of 0-14 years old were studied. Among 110 bacteriologically confirmed cases, 60% were less than five years old and the number of females was slightly more than males. In 21 % of patients, the Mantoux test was negative. None of the miliary cases had a history of BCG vaccination. In 54.6% of patients less than two years old, one of the family members was suffering from infectious tuberculosis. Clinical findings were fever, cough, weight loss and respiratory distress respectively. Radiological findings were mostly pneumonia or bronchopneumonia-like infiltrations and in 44% of cases were found in the right lung. Mycobacterium tuberculosis strains in 11.7% of patients were resistant to isoniazid or streptomycin.}, Keywords = {}, volume = {4}, Number = {1}, pages = {1-4}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1562-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1562-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1990} }