@article{ author = {M.LARI, MANOOCHEHR and KHOSSRAVY, AHMAD and GHIASSI, TAGHI}, title = {CARCINOMA OF THE ESOPHAGUS IN A FOURTEEN YEAR OLD BOY}, abstract ={This is the first documented case of esophageal carcinoma in a 14 year old boy which has been reported to date. Carcinoma of the esophagus is rare before the third decade. The present case highlights the fact that the condition should be kept in mind in the differential diagnosis of progressive dysphagia even in children and teenagers}, Keywords = {Esophageal carcinoma, Epidemiology. Dysphagia, Teen-age}, volume = {8}, Number = {4}, pages = {277-280}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1370-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1370-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {KALANTARMOTAMEDI, MOHAMMAD HOSEIN and KALANTARMOTAMEDI, MOHAMMAD HASAN and KALANTARMOTAMEDI, MOHAMMAD REZA and YAZDI, ISMAIL}, title = {MANDIBULAR OSTEOSARCOMA MISTAKEN FOR PERICORONAL INFECTION A CASE REPORT}, abstract ={Osteosarcoma is relatively rare in the jaws and variable in presentation, thus its recognition may be quite confusing and delay diagnosis and treatment. Also, in contrast to most malignancies, osteosarcoma is usually encountered earlier in life and may clinically resemble features of more common oral entities such as chronic osteomyelitis, fibrous dysplasia, osteoblastic metastatic carcinoma, ossifying subperiosteal hematoma and chondrosarcoma. Hence definitive treatment may be inadvertently delayed, jeopardizing the chance for cure. A case of chondroblastic osteosarcoma of the mandible which was mistakenly treated as a pericoronal infection by a dentist is presented. The treatment instituted was continued for several weeks despite progression of the lesion, after which the patient was referred. This delay made necessary a more radical resection than that which would have been needed had the patient been referred earlier.}, Keywords = {}, volume = {8}, Number = {4}, pages = {271-275}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1369-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1369-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {EMAMIAL-AGHA, MOHSEN and ATHARI, AMID}, title = {SUBCU TANEOUS FASCIOLIASIS: A RARE COMPLICATION}, abstract ={A case of ectopic fascioliasis due to migration of an immature Fasciola hepatica fluke is described in a 23 year old woman from western Iran.}, Keywords = {}, volume = {8}, Number = {4}, pages = {269-270}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1368-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1368-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {AYATOLLAHl, SEYYED MOHAMMAD TAGHI}, title = {ISLAMIC MEDICAL JURISP RUDENCE PART II: THE RESPONSES OF ISLAMIC LAW TO MEDICAL DILEMMAS}, abstract ={Judicial decisions (Fatawa) of some of the most learned juridical authorities in the Imamate (Shiite) community (maraja' al-taqlid) of present time on medical issues are examined in this paper. They will provide the reader with the responses of the Islamic jurisprudence to the most involved medical dilemmas. The paper mainly focuses on the rational viewpoints of the Islamic law on permission of family planning and birth control, strict ban of abortion especially when the embryo is four months and above in normal conditions, and legitimacy of artificial insemination by the husband. Judicial prescription of cadaver and organ donation and transplantation are also discussed in some detail. The religious rite of circumcision and its impac! on the health of man is duly elaborated and the principles of medical examination explained. The principle of priority of saving human life prevails all forbidden rulings set out for observing human sanctity in ordinary cases. Also, the principle of necessity when no definitive ruling is available on a given issue, has been an important source for religious prescription in all matters pertaining to the welfare of the Muslim society.}, Keywords = {}, volume = {8}, Number = {4}, pages = {259-268}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1367-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1367-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {REZAIAN, M and GHALHARI, SM}, title = {AXENIC CULTURE AND CRYOPRESERVATION OF GIARDIA LAMBLIA ISOLATED IN IRAN}, abstract ={Giardia lamblia cysts were isolated from fecal samples of 55 symptomatic and asymptomatic patients with giardiasis. The cysts were harvested and purified using the sucrose gradient method. IS The excystation of G. lamblia was obtained by treating them with HCI (0.01N)', then they were transferred on to modified TYI-S-33 medium. Out of 55 stool samples 17 cases were excysted with a rate of 4-32%,but we were able to cultivate only one case with 12% excystation in culture medium. The generation time of G.lamblia was calculated to be about 10.33 hours. Cryopreservation of trophozoites was successfully done in liquid nitrogen and the thawing process had a survival rate of 85-90%.}, Keywords = {}, volume = {8}, Number = {4}, pages = {255-258}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1366-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1366-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {BOOJAR, MASSOUD and RABBANI, AZRA}, title = {THE EFFECT OF THEOPHYLLINE ON THE KINETICS OF cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, cAMP, PROTEIN KINASE INHIBITOR AND THEIR RELATIONSHIP IN LUNG TISSUE}, abstract ={We have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. The results show that the point of highest concentration of the C subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 Ilg/ InL and 10µg/mL theophylline, this is shifted to I.S and 2.S hrs, respectively. Also the maximum concentration of cAMP for the control is at 2.S h of incubation time, butin the treated samples shifts to 2.15 and LIS hrs, respectively. Inhibitor protein content also changes considerably in the presence of 10µg/mL theophylline. The results suggest an effect of theophylline on the function of cAMP-dependent protein kinase.}, Keywords = {Theophylline, cAMP, catalytic; subunit, inhibitor protein, protein kinase}, volume = {8}, Number = {4}, pages = {249-253}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1365-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1365-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {ASADYKARAM, GHR and RASAEE, MT}, title = {DEVELOPMENT OF A SIMPLE AND SENSITIVE ENZYME- LINKED IMMUNOSORBENT ASSAY (ELISA) FOR CLINICAL MEASUREMENT OF TESTOSTERONE USING PENICILLINASE AS LABEL}, abstract ={An enzyme-linked immunosorbent assay using a homologous combination of antiserum raised against testosterone-3-0-carboxymethyloxime-bovine serum albumin (T-3-0-CMO-BSA ) and penicillinase-labelled T-3-0-CMO was developed. This assay was utilized to measure testosterone in serum samples of male and female subjects. The sensitivity of the assay is 50pg/well and the antibody developed crossreacted in less than 20% with 5α-dehydrotestosterone (5α DHT) . lnter- and intraassay variations and all other validation factors such as recovery, test of parallelism, etc. were well in the acceptable ranges. Comparison of testosterone values of 32 plasma specimens obtained by solid phase ELISA method and radioimmunoassay (RIA) showed a good correlation (0. 96).}, Keywords = {}, volume = {8}, Number = {4}, pages = {243-248}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1364-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1364-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {NILFOROUSHAN, MOHAMMAD ALI and HASHEMI, FARAH and MALEKAFZALI, HOSEIN}, title = {COMPARISON OF GROWTH CHARTS OF 1-36 MONTH OLD TEHRANI CHILDREN WITH THE N.C.H.S.l CURVE}, abstract ={During a historic prospective study, measurements of weight, height and head circumferences were carried out in a group of 393 Tehrani boys and girls between the first and 36th month of life and measurements were plotted over the N.C.H.S. curves. These children belonged to middle and high-class literate families who were able to understand and follow the medical advice given by their private pediatricians. Results of this study (Table I and Figs. 1-6) indicate that the trend of growth of this sample of middle and high-class Tehrani children does not differ from N.C.H.S. standards, provided that the parents understand and follow the instructions given with regards to diet, timing, and type of introduction of foods as well as hygienic and preventive measures to be taken.}, Keywords = {}, volume = {8}, Number = {4}, pages = {237-242}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1363-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1363-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {GOLCHAI, JAVAD and MOBARHANVAGHEKAREGAR, MOHAMMAD MEHDI}, title = {THERAPEUTIC EVALUATION OF INTRALESIONAL INJECTION OF BLEOMYCIN SULFAT E IN THE TREATMENT OF RESISTANT WARTS}, abstract ={From June 1992 to March 1993, a group of patients suffering from different types of warts were treated with intralesional injections of bleomycin sulfate. This study reviews the literature concerning this modality of treatment and the pathophysiology and immunohistopathology of warts and options for treatment. In this prospective study, a combination of a I mg/mL solution of bleomycin in distilled water and lidocaine 2% (in equal portions) was injected in 22 patients. No patient received more than 2mL of the solution. Eighty-four of 95 warts (88.4%) showed complete resolution after 1-3 bleomycin injections, while 10 warts (10.5%) showed incomplete resolution. In only one plantar wart did bleomycin fail to elicit any therapeutic response (1.1%).The cure rate was 96.3% for periungual warts, 84.6% for palmoplantar warts, and 75% for warts located on the extremities. The responsive warts developed a hemorrhagic eschar that healed without scarring. No systemic side-effects were observed but a mild transient pigmentary change was seen at the injection site of one palmar wart. It is concluded that this form of treatment for resistant warts is safe, reliable and well accepted by the patients if used in the dose mentioned.}, Keywords = {Resistant warts; Bleomycin sulfate}, volume = {8}, Number = {4}, pages = {233-236}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1362-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1362-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {AFRASIABI, MORTEZA and ZOLNOORIAN, ZAHRA and JAVADPOOR, SEYYED HOSSEIN}, title = {PHARMA COKINETICS OF RECOMBINANT ERYTHROPOIETIN AND RED CELL METABOLISM IN HAEMODIALYSIS PATIENTS}, abstract ={The pharmacokinetics of recombinant human erythropoietin (rHuEpo) administered intravenously has been investigated in a group of five patients with chronic renal failure who were dialysis-dependent. The half-life of circulating erythropoietin decreased from 7.9±OA hr (mean ±SO) at the beginning of treatment to 6.2±O.6 hr after 6 weeks and 5A±O.9 hr after 4 months of treatment. In spite of the sustained increase in haemoglobin neither the red ce1l2,3,-diphosphoglycerate (2,3- DPO) nor the P50 decreased from the pretreatment values. The mechanism which governs the rise in 2,3-diphosphoglycerate in chronic renal failure is different from the adaptive mechanism which operates in other types of anaemia.}, Keywords = {Recombinant Erythropoietin. Red Cell Metabolism, Chronic Renal Failure}, volume = {8}, Number = {4}, pages = {229-231}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1361-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1361-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {ZIAEI, SAElDEH}, title = {IS THERE ANY RELATION BE TWEEN ESTROGEN LEVEL AND P OOR CERVICAL MUCUS IN PA TIEN TS RECEIVING CLOMIPHENE CITRATE?}, abstract ={Clomiphene citrate (CC) has an adverse effect on the quality and quantity of cervical mucus (CM). Poor cervical mucus has been reported in 15% of CC-treated women. CC exhibits estrogen agonist and antagonist activities. Antiestrogenic activity affecting the endocervical glands is theorized to cause a decrease in cervical mucus quality and quantity. An experimental study was performed to assess if there is any relation between poor CM and the level of estrogen in those to whom the drug is administered. We used CC on 50 subjects and evaluated CM and measured serum E2 levels simultaneously. We concluded that there is no relation between the level of estrogen and the quality or quantity of CM in these patients.}, Keywords = {}, volume = {8}, Number = {4}, pages = {225-227}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1359-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1359-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {ROODPEYMA, SHAHLA}, title = {INFECTIVE ENDOCARDITIS IN CHILDREN}, abstract ={A total of 14 cases of infective endocarditis (IE) in children aged 6 months to 10 years were seen from December 1987 to December 1992 at the pediatric unit of Ayatollah Taleghani Medical Center. The majority of patients (12 of 14) were between 5 and 10 years of age. Acyanotic congenital heart disease was known to preexist in 78.6% and rheumatic valvular heart disease in 21.4% of cases. Organisms were identified by blood culture in 50%, the majority being Streptococcus viridalls (36% of cases). Vegetations were detected by echocardiography in 64%. The overall death rate was 21.4%. Two patients with aortic stenosis developed IE after cardiac surgery for repair of stenotic valves and both of them died. One patient with rheumatic aortic and mitral valve insufficiency underwent valve replacement due to intractable heart failure. In conclusion, the frequent presence of underlying heart disease, the rarity of IE in infancy, and the ominous prognosis of postoperative endocarditis and aortic valve involvement are emphasized.}, Keywords = {Children. Infective endocarditis (IE). Congenital heart disease (CHD). Valvular heart}, volume = {8}, Number = {4}, pages = {221-224}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1358-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1358-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {RAISSI, KAMAL and SINA, MOHAMMAD and KALANTARMOTAMEDI, MOHAMMAD HASAN}, title = {CAUSES OF MORTALITY IN CARDIAC SURGERY REOPERATIONS}, abstract ={From March 1990 to May 1993,309 patients underwent redo cardiac surgery operation at the Shahid Rajai Heart Hospital in Tehran. Early mortality rates in these patients showed a significant increase in comparison to patients undergoing open heart surgery for the first time. Late mortality (at least one month after surgery) in the patients was slightly increased also but less than early mortality rates. The causes and factors involved in mortality of the patients are discussed in detail. Comparison of mortality rates in our patients with that reported in the literature reveals similar mortality in these patients, and thus the presence of definite and irrefutable factors which influence this risk. These factors consist of the patients' function class, age, surgical procedure, number of prosthetic valves in place, duration of cardiopulmonary bypass, degree of hypothermia and duration of myocardial ischemia. These factors are evaluated in this report.}, Keywords = {Redo cardiac surgery, mortality rate.}, volume = {8}, Number = {4}, pages = {217-219}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1357-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1357-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {MOHEBALI, M and JAVADlAN, EH and FESHARAKl, R and MOHAMMADZADEH, M and NADlM, A and TAHYILDAR-BIDRUNI, GH and MESDAGHINIA, A}, title = {TRIAL OF A NON-LIVING CRUDE VACCINE AGAINST ZOONOTIC CUTANEOUS LEISHMANIASIS}, abstract ={A field trial was canied outon60 volunteers selected in Yazd province, central Iran, with a vaccine containing killed promastigotes of L. major prepared by the Razi Institute, Hessarak. During these phase I studies which lasted for more than two years, we examined acceptable doses of the vaccine alone or mixed with BCG. The results so far indicate that 50 to 1000 µg of the vaccine alone can be well tolerated without major side-effects. The mixture of BCG with 400 µg of the vaccine produced pain and itching in five out of six volunteers, a self-limiting lymphadenopathy in one out of six, and fever in three out of six. Further trials are planned with reduced doses of BCG. The leishmania skin test became positive in a high proportion of the treated individuals after vaccination. Circulating antibodies were detected from two weeks to one month after vaccination.}, Keywords = {}, volume = {8}, Number = {4}, pages = {211-215}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1356-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1356-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1995} } @article{ author = {SATTARI, MORTEZA and MOAZAMI, NASRIN and ZULFAGHARI, MOHAMMAD ESMAlL}, title = {PRODUCTION OF OXYTETRACYCLINE BY ISOLATED WILD TYPE IRANIAN STREPTOMYCES RIMOSUS}, abstract ={Production of oxytetracycline by an isolated strain of Streptomyces rimosus from Iranian soil was investigated using a special fermentation medium. A comparative study was performed with standard strain PTCC 1144 using the following parameters optimum growth conditions with respect to time, pH, and different amounts of corn steep liquor. Surprisingly, the production yield of the wild strain was 20% more than the standard strain.}, Keywords = {Oxytetracycline, Streptomyces rimosas, Production.}, volume = {8}, Number = {3}, pages = {187-189}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1380-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1380-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {J.KUCHARZ, EUGENE and KOTT, THERESA}, title = {HEPATOPROTECTIVE ACTIVITY OF SILYMARIN IN RATS TREATED WITH HIGH DOSES OF ACE T YLSA LICYLIC ACID OR NAPROXEN}, abstract ={Rats were treated with acetylsalicylic acid (150 mgikg b.w.per os daily) or naproxen (125 mg/kg b.w. per os daily) for six weeks. Half of the rats received silymarin (17.5 mgikg b.w. per os daily) in the last three weeks of the experiment. It was found tliat administration of acetylsalicylic acid led to signs of hepatic damage (an increase in serum bilirubin level, alanine aminotransferase and ү-glutamyl transpeptidase activity) while the concomitant administration of silymarin diminished the extent of the hepatic damage. Naproxen was shown to be less toxic than acetylsalicylic acid, and its toxicity was also reduced by silymarin. The obtained results suggest that silymarin be administered to patients undergoing long-term treatment with non-steroidal anti-inflammatory drugs in order to prevent hepatic damage, but further studies are needed to elaborate on the clinical aspects of silymarin treatment in those patients.}, Keywords = {}, volume = {8}, Number = {3}, pages = {183-185}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1379-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1379-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {GOLIAEI, BAHRAM and TAHERI, MARYAM and RABBANI, AZRA}, title = {F EEDBACK REGU LATION OF COLONYSTIMULATING FACTOR PRODUCTION}, abstract ={The production of colony-stimulating factors (CSF) is delicately controlled through a complex network of humoral and environmental factors. We have studied some of the mechanisms which regulate the production of CSF as compared to general protein synthesis in the lung tissue ill vitro. When lung tissue from mice was cultured for various times in serum free medium, the first detectable level of CSF activity in the lung conditioned medium (LCM) appeared 6 hr after initiation of the culture, continued to rise until 24 hr, and then levelled off for several days. Under similar conditions protein synthesis did not level off, but continuously rose after 24 hr. When the lung tissue which had been cultured previously for 6,24, or 4X hr was recultured in fresh tissue culture medium, de IIOVO synthesis of CSF occurred as judged by CSF synthesis inhibition and stimulation studies. The amount of new CSF synthesized by these tissues decreased as the initial culturing period increased from 6 to 4X hr. There was also a decrease in the amount of total protein synthesis and release in the secondary lung cultures as a function of the initial culturing period. Endotoxin stimulation of 24 or 4X hrcultured lung tissues (plateau phase tissue) resulted in de IIOVO synthesis of CSF by these tissues. However, when fresh lung tissue was cultured in 24 or 4X hr LCM, no new CSF was produced by the fresh tissues, while under similar conditions, protein synthesis by these tissues was significant as judged by double-labelling experiments. On the other hand, n hr LCM was able to support both CSF production and protein synthesis by fresh lung tissues. The results suggest at least two distinct regulatory systems controlling CSF production by the lung ill vitro: 1- Aging which is responsible for general and nonspecific decrease in the rate of protein synthesis and CSF production in this system, and 2-Feedback regulation of CSF production by the level of CSF which is formed in the LCM.}, Keywords = {}, volume = {8}, Number = {3}, pages = {177-182}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1378-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1378-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {MIRDAMADI, SAEED and MOAZAMI, NASRIN and RAFIEETEHRANI, SHAHNAZ}, title = {DETERMINATION OF DOMINANT SEROVARS OF LISTERIA MONOCYTOGENES}, abstract ={Serovars of Lisreria l1Iollocyrogelles were determined. Sera of aborted samples (200) were collected from different hospitals in Tehran and were tested serologically by immunofluorescent antibody methods (IF tests). 137 positive sera were identified. Positive sera were tested against 12 serovars of Listeria l1Iollocytogelles separately. Titers of antibody in patients' sera for all serovars were determined. The results showed that the dominant serovars of L.l1Iollocyrogelles which caused listeriosis in the samples were 4b, la, 2 and 3. None of the sera had antibodies against serovars 4a, oa or (ib. Some of the sera which had high titers of antibody against dominant serovars (4b, I a, 2 and 3), showed a faint result with serovars 4d, 4e,5 and 7.}, Keywords = {}, volume = {8}, Number = {3}, pages = {173-175}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1377-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1377-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {JANGHORBANI, MOHSEN and ZARKOOB, SIMIN}, title = {EPIDEMIOLOGY OF PRIMARY DYSMENORRHEA IN KERMAN, IRAN}, abstract ={The prevalence and factors influencing the prevalence and severity of dysmenorrhea were studied in 768 female university students aged from 17.S to 44.2 years enrolled at the Kerman University of Medical Sciences and two teachers' training colleges. The overall prevalence of dysmenorrhea in this population was 72% 10.2% reported severe dysmenorrhea. The overall prevalence as well as the prevalence of severe dysmenorrhea decreased with age. A statistically significant association (P<0.05) was found between an early age of menarche and an increase in the severity of dysmenorrhea. There was also a statistically significant association (P<0.01) between the prevalence and severity of dysmenorrhea and marriage, and married women had significantly less dysmenorrhea (either in severity or prevalence) compared to non-married subjects. The prevalence and severity of dysmenorrhea was not affected by factors such as height, weight, body mass index, region of residence, gynecological age, regularity of menstrual cycles, or duration or amount of menstrual bleeding.}, Keywords = {Dysmenorrhea, Prevalence, Epidemiology, Iran, Adolescence, Primary dysmenorrheal}, volume = {8}, Number = {3}, pages = {167-171}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1376-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1376-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {RAIANI, M and MASSOUD, A and DAVATCHI, F}, title = {LEVELS OF SOLUBLE IL-2 RECEP TORS IN SERA OF IRANIAN PATIENTS WITH BEHCET\'S DISEASE}, abstract ={It has been shown that activated T-cells produce and release both IL-2 and IL- 2 receptors (lL-2R). The rate of IL-2 release is proportional to its cell surface expression and state of cell activation. To clarify the molecular basis of this immunological aberration, we analysed the amount of soluble IL-2R(SIL2-R) by an ELISA technique in 68 patients with Behcet's disease (BD), 28 patient controls (PC) and 31 normal controls (NC). The data suggest that the amount of SIL-2R in BD is significantly higher (P<O.005) than that of NC. The same differences were seen between PC and NC(P<O.005). However the level of S IL-2R in BD and PC were similar. This study suggests that inhibition of an immunoregulatory cytokine by its soluble receptors might occur ill vivo, as the reduction ofS IL-2R levels approaching control values preceded clinical remission.}, Keywords = {}, volume = {8}, Number = {3}, pages = {163-166}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1375-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1375-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {ADIB, KM and HOSSEINI, H}, title = {ASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN}, abstract ={Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.}, Keywords = {}, volume = {8}, Number = {3}, pages = {159-161}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1374-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1374-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {YAZDANPARAST, K and DEHBASHI, N and MANSOURGHANAIE, F}, title = {CLINICA L FINDINGS IN PATIENTS WITH ACUTE AMEBIC PROCTOCOLITIS A ND EFFICA CY OF COMBINED THERAPY WITH SACCHAROMYCES BOULARDII}, abstract ={Intestinal amebiasis has a worldwide distribution and is common in tropical and subtropical areas. [n this prospective 7-month study, we studied the main clinical findings in patients with acute amebic proctocolitis and the efficacy of Saccharomyces boulardii (SB) treatment of these patients.Initially, 57 cases with acute amebic proctocolitis were selected. The maximum occurrence of infection was found to be in the 30-39 year old age group. The patients were then randomized to two therapeutic regimens. The first included metronidazole 750 mg P.O. tid X 1 0 days and iodoquinol630 mg P.O. tid Xl 0 days, and the second was the latter plus S. boulardii 250 mg P.O. tid x 10 days. The diarrhea, abdominal pain and fever were significantly decreased after initation of therapy in patients receiving regimen IT as compared with patients of regimen 1. Four weeks after the end of treatment, the two groups were examined for carrier states (presence of amebic cysts in stool, without symptoms). [n regimen I, the percentage of carriers was [1).4%, but in the patients who received regimen IT, no carriers were found (P= 0.025).}, Keywords = {Intestinal amebiasis, S. boulardii, Metronidazole, Iodoquinol}, volume = {8}, Number = {3}, pages = {155-157}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1373-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1373-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {RAFIEI, S and NAKHJEVANI, M and GHARAGOUZLOU, M}, title = {AUTOANTIBODIES AGAINST THYR OID CONSTITUENTS AND CIC IN GRAVES\' DISEASE ASSOCIATED WITH EXOPH THALMUS}, abstract ={32 patients (19 female. 13 male)• suffering from Graves' disease with exophthalmus and five without exophthalmus were studied for various autoantibodies including anti-thyroglobulin (ATAB). anti-microsomal antibody (AMAB). anti-parietal antibodies (APAB) and also circulating immune complex (CrC). 43 normal subjects were tested concurrently. Immunofluorescent technique was employed for autoantibody detection. Frozen sections of human thyroid tissue and rat stomach were utilized as antigen sources for thyroid and parietal CIC estimated by PEG (polyethylene glycol) precipitation method and the specific classes of immunoglobulins were detected by SRlD (single radial immunodiffusion). The results were analyzed statistically. From the point of view of presence of antibodies. there were significant differences between patients and control groups (P= 0.(05). Comparing Graves' with or without exophthalmus. no significant difference was seen between autoantibody levels. but higher titers of CIC were elucidated in the latter group. We will discuss that autoantibodies have an important role in thyroid autoimmune diseases and also that CIC may have a critical role in the pathogenesis of exophthalmus associated with Graves' disease}, Keywords = {}, volume = {8}, Number = {3}, pages = {149-153}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1372-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1372-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {KALANTARMOTAMEDI, MOHAMMADREZA and KALANTARMOTAMEDI, MOHAMMADHASAN}, title = {CAROTID BODY TUMORS OUR EXPERIENCE WITH 20 PATIENTS}, abstract ={In this report of 20 patients with 24 carotid body tumors which is the largest series reported so far from Iran, we have evaluated the various characteristics of this relatively rare tumor in our population and compared our results with that of the literature. Although the prevalence of the tumor is cited to be equal among both sexes, we found a female to male ratio of 2.3 to I, as 14 of our patients were female and 6 were male. The tumor was as equally frequent on the right as it was on the left, and was bilateral in four cases. The average tumor size was 5.3 cm in diameter and was found to be malignant in four cases. The results we obtained following the careful surgical technique which is described in detail compares quite favorably with that in the literature: 3 cases of cranial nerve injury (12.5%) compared to an average of 45% nerve injury in the reports, and no perioperative death versus 2% perioperative mortality in the literature. Also we had no instances of stroke, transient ischemia, Horner's syndrome, or other complications. We propose the surgical technique detailed by the author as the method of choice for treatment of carotid body tumors in Iranian patients.}, Keywords = {}, volume = {8}, Number = {3}, pages = {141-147}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1371-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1371-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {RAZZAGHI, MR and HONARMAND, AR and RAFII, MR}, title = {NEUROFIBROMATOSIS PRESENTING AS SCROTAL ELEPHANTI ASIS}, abstract ={Neurofibromatosis being manifested as scrotal elephantiasis is a very rare condition and in review of the literature no such presentation was found. Here we report a 20 year old man who presented with scrotal elephantiasis and consequently, a pathological diagnosis of neurofibromatosis was reached.}, Keywords = {Scrotal mass. Neurofibromatosis. Elephantiasis, Scrotal lymphedema}, volume = {8}, Number = {2}, pages = {137-139}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1394-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1394-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {MORTAZAVI, MASOUD}, title = {NEUROGENIC TUMORS OF THE NOSE AND P OSTNASAL SPACE}, abstract ={Non-epithelial, benign extracranial neurogenic tumors of the nasal cavities are reported in the literature with extreme rarity. These tumors differ from the more common congenital gliomas, encephaloceles, etc. in that they sometimes are detached from the brain tissues. These tumors have intracranial origins. They are congenital or acquired and may involve any of the nerves inside the nose. These tumors can grow to quite a large size and in such cases, lateral rhinotomy is often necessary for complete excision.}, Keywords = {}, volume = {8}, Number = {2}, pages = {133-135}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1393-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1393-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {MAHLOUJI, KH}, title = {MULTIPLE ENCHONDROMATA: OLLIER\'S DISEASE}, abstract ={This report is a brief presentation of one case of Oilier's disease. Ollier's disease (multiple enchondromata) patients have widespread involvement of the skeleton, especially the hands the lesions are detected because of bone pain or deformity. Virtually all cases have been sporadic. Roentgenographically, the lesions may be detectable in early infancy as clear, homogeneous, oval lesions with axes parallel to the longitudinal axis of the bone.}, Keywords = {}, volume = {8}, Number = {2}, pages = {129-131}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1392-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1392-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {GOLCHAI, J and SHAMSGILANY, J}, title = {TUFTED HAIR FOLLICULITIS}, abstract ={A 28 year old albino man presented with a cicatricial alopecic plaque on the vertex. The patient had multiple hairs emerging from a single dilated follicular opening. Following inflammatory changes, new tufted hair appeared in spite of several periods of antibiotic treatment, and the disorder followed a relapsing and destructive course. Tufted hair folliculitis (THF) is a relapsing localized inflammatory disease of the scalp. Unfortunately, this situation results in cicatricial alopecia. This disease, initially designated as "THF" by Smith and Sanderson in 1978, has been reported in only 10 patients to date.}, Keywords = {Tufted folliculitis, Scalp folliculilis}, volume = {8}, Number = {2}, pages = {127-128}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1391-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1391-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {AYATOLLAHI, SEYYED MOHAMMAD TAGHI}, title = {ETHICAL ISSUES IN MEDICAL STATISTICS}, abstract ={Medical statistics (biostatistics), as a vital essential part of modem life, does raise some fundamental ethical issues. Surprisingly, this aspect seems to have been totally ignored by books on medical ethics. This paper discusses how the statistical aspects affect the ethics. The relation between biostatistics and medical research is explored. All stages of a medical research exercise are vulnerable to statistical mismanagement which might lead to misuse of patients by exposing them to unjustified risk and inconvenience the misuse of resources including the researchers' time, which could be better employed on more valuable activities and the consequences of publishing misleading results, which may include carrying out unnecessary further work. These are specific and highly undesirable outcomes. Failure to guard against these is surely as unethical as using experimental methods that offend against moral principles, such as failing to obtain full informed consent from subjects. Raising statistical standards of medical researches and publications serves as a safeguard to observe the element of ethics. This can be achieved by widespread teaching of medical statistics at all levels, involvement of biostatisticians as active participants of any medical researches and ethical committees. Ethical issues in medical statistics require wider and more open debate. Those involved in medical research need to involve the whole medical profession. lndeed, moral philosophers, theologians, and other professional groups have an important contribution to make.}, Keywords = {}, volume = {8}, Number = {2}, pages = {121-125}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1390-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1390-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {}, title = {THE ROLE OF RELIGION AND ETHICS IN THE PREVENTION AND CONTROL OF AIDS}, abstract ={Itis unlikely that mankind has ever faced an epidemic as dangerous as the one we have come to call the Acquired Immunodeficiency Syndrome or AIDS, for short. Certainly, humanity has never given so much attention to or shown so much fear of a disease as it does with AIDS. AIDS is a terminal disease for which doctors have no effective cure as yet. Infection is predominantly through sexual intercourse performed under certain circumstances or in certain ways. Apart from this, no one knows when it first afflicted humans, nor can anybody predict, let alone claim to know, what will befall the human race as a result of its spread over the coming years. The mystery surrounding this disease is made much more complicated by the fact that, years after it was fust discovered, it became clear that its infection had been widespread in many countries before the disease was even detected by scientists and before the fust AIDS case was diagnosed in 1981. Scientific sources concerned with monitoring the spread of AIDS point out that by the year 2000, the number of cases is likely to reach 40 million, of which 30 million will be among adults and the rest among children. The same sources say that if the spread of AIDS continues unchecked, with no effective and accessible cure becoming available to those infected, the number of cases is likely to reach uncontrollable proportions. The present situation is no better than that which is being predicted for the future. The World Health Organization (WHO) believes that between 300,000 and 500,000 people will suffer symptoms of AIDS every year, i.e., between 1,000 and 1,400 cases a day.' All this no doubt justifies the horror expressed by the concerned agencies and institutions, as well as by ordinary people. It also justifies the interest shown by various specialist bodies, headed by WHO, in providing information, advice and knowledge with regard to prevention methods against this very serious disease. With scientific and medical efforts still unable to find a vaccine or a cure that would protect people against the AIDS epidemic and its horrors, the only way to combat the disease is through prevention, slaving off the evil before it strikes and keeping away from the sources of danger. Nothing can be more helpful in this preventive effort than religious teachings and the adoption of proper and decent behaviour, as advocated and urged by all divine religions. The World Health Organization, and the Eastern Mediterranean Regional Office in particular, have conducted some experiments in this field. In the health programmes carried out in collaboration with Member States, it has taken account of indigenous traditions and cultures that are basically built on religious beliefs. The effect has been tremendous, as can clearly be seen in encouraging public reponse to these programmes. Accordingly, WHO's Eastern Mediterranean Regional Office took the initiative to organize a Regional Consultation on the Role of Religion and Ethics in the field of the prevention and control of AIDS and other sexually transmitted diseases to which a select group of experts in the fields of religion and medicine have been invited. The Consultation was held on 9 and 10 September 1991, at the Eastern Regional Director and a larger number of directors and advisers at the Regional Office. It was also attended by ten prominent legal and religious scholars, both Muslim and Christian (See Annex II). A number of papers were submitted and distributed for study and consultation. As a result, several recommendations and conclusions were formulated (Annex I). These dealt with the importance of religion and its role in the field of prevention of AIDS and other sexually transmitted diseases. They also highlighted the role of religious establishments and the media, the rights of victims and those who come in contact with them, the effect of prevention and diagnosis procedures on human rights, early marriage, the laws dealing with patients and infected persons, and doctors' duties. The aim of this booklet is to introduce the role of religion and ethics in the prevention and control of AIDS and sexually transmitted diseases, and to convey a strong and direct message of warning about the risks and side effects of misbehaviour. It also urges people to observe religious teachings and cherish moral and ethical values that prevent individuals from getting involved in risky relationships. Furthermore, it aims to encourage them to develop the necessary self-control to prevent them from such dangerous practices, whose risks for human life as a whole are not yet fully understood. It has "become very clear that the factors and conditions leading to infection by AIDS and other sexually transmitted diseases can be avoided if people adopt proper and decent patterns of behaviour, and if they adhere to the fundamental teachings of religion and the moral ethos based on them, which have become the central component of the unique culture of the people of this Region, and their inherited traditions" .42 Finally, the Regional Office is pleased to present the reader with two documents on this subject the fust one is the full text of the recommendations of the Regional Consultation on the Role of Religion and Ethics in the Prevention and Control of AIDS and other Sexually Transmitted Diseases (Alexandria, September 1991), and the second is "Health Promotion through Islamic Lifestyles: the Amman Declaration" (June 1989, and the reference document attached to it.) These two documents, which we hope will help readers learn more on the subject of the present booklet, are included in issue number 5 of the Health Education through Religion series.}, Keywords = {}, volume = {8}, Number = {2}, pages = {115-119}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1389-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1389-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {A.GHADERI, ABBAS and AMIRGHOFRAN, ZAHRA}, title = {CD38 MOLECULE-A MULTILINEAGE GLYCOPROTEIN AND ITS UNIQUE EXPRESSION ON PLASMA CELLS}, abstract ={A hybridoma clone designated 6G5 has been selected by fusion of mouse myeloma cell line Ag. 8653 with spleen cells from mice immunized with human peripheral blood mononuclear cells (PBMC). The antibody produced by this clone was found to be strongly reactive with four human B-cell lines in the conventional immunological assays. Despite the fact that expression of most B cell-associated markers are lost upon differentiation of B-cells to plasma cells, the expression of the 6G5 reactive molecule remains unchanged. The lack of reactivities of this MAb for mature T-cells, and monocytic cell lines indicates that this MAb recognizes a B cell associated marker. Western blot analysis indicated that the 6G5 MAb detected a single band with molecular weight of 41 KDa from cell lysates of two human B-cell lines, DAUDI and NALM6. Comparison of data obtained for 6G5 MAb with those of the MAb known as OKTIO indicated that both MAbs may have reacted with the same molecule.}, Keywords = {}, volume = {8}, Number = {2}, pages = {109-113}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1388-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1388-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {NOORI-DALOII, MR and MOAZAMI, N and IZADYAR, M and FARHANGI, S and BEYRAMIJAMAL, F and ATALAY, A and GEREN, LN and AKAR, L and ATALAY, E and CIRAKOGLU, B and BERMEK, E}, title = {MOLECULAR STUDIES ON THE DIST RIBUTION OF β - THALASSEMIA IN IRAN: THE BASIS FOR PRENATAL DIAGNOSIS}, abstract ={By application of modern recombinant DNA technology, especially the polymerase chain reaction (PCR)/dot-blot hybridization techniques, we have investigated the molecular basis of β-thalassemia from four different regions of Iran: central, south-east, south and north. In this study, the DNA samples were isolated from patients and for the identification of the mutations, the 6 oligonucleotide probes for the mutations of IVS.1/nt. 110, .lVS.1/nt.6, IVS.1/nt.1 , nonsense codon 39, frameshift codon 8 and IVS. 2/nt.1 were selected with respect to their relative frequency in the neighbouring country, Turkey. Four mutations accounted for76.2% and of these, the most frequent was the nonsense codon 39 mutation, which accounts for 60.3% of the β-thalassemia alleles tested. The remainder, in decreasing order of frequency, wereframeshift codon 8(9.5%), lVS. 1/nt.6 (4.8%) and IVS.1/nt.11O(1.6%). No hybridization was observed with the probes corresponding to the mutations of rvS.I/nt I (0/ A) and rvS.2/nt.1 (0/ A). These results also revealed that the distributions of different types of mutations were different in the four regions. This information and the introduction to the methodology used in this study will facilitate the prenatal diagnosis of the disease in Iran.}, Keywords = {β-Thalassemia, β-Globin gene mutations. Polymerase chain reaction, Molecular}, volume = {8}, Number = {2}, pages = {101-107}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1387-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1387-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {OMRANI, GHR and FARHADl, A and PARHlZGAR, A and ARDEHALl, S and HAGHSHENAS, M}, title = {VISCERAL LEISHMANIASIS AS FEVER OF UNKNOWN ORIGIN}, abstract ={Visceral leishmaniasis is the second most common cause of fever of unknown origin in our study. This disease is not common in adults, although it's endemic among the pediatric age group. The majority of the affected individuals were young. High grade spiking fever, chills and splenomegaly were unique findings. Other common findings were neutropenia, anemia, abnormal liver function tests, sterile pyuria and microscopic hematuria. Except for I case, parasites were absent from tissue biopsies (e.g. bone marrow, liver, lymph node). Diagnosis was suggested by indirect fluorescent antibody (IFA) and confirmed by response to meglumine antimonate (Glucantime) and decline of IFA titer on follow-up.}, Keywords = {F.U.O .. Leishmaniasis.}, volume = {8}, Number = {2}, pages = {97-100}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1386-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1386-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {ATHARI, A and SHOJAEIAN, S and ELIASI, O and DELFANI, K}, title = {SEROPREVALENCE OF TOXOPLASMA ANTIBODIES AMONG PREGNANT WOMEN IN KERMAN SHAH}, abstract ={Sera from 495 pregnant women were examined for toxoplasma antibodies by indirect fluorescent antibody testing (IFAT). Antibodies were positive in 32.7%. Seropositivity was not increased significantly with age but showed a statistically significant rise in accordance with frequency of parity, abortion and contact with cats. The high rate of seronegativity (67.3%) observed in pregnant women represents a high risk group for acquiring toxoplasma infection and also congenital toxoplasmosis.}, Keywords = {}, volume = {8}, Number = {2}, pages = {93-95}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1385-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1385-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {GHAZISAIDI, KIUMARS and L.STANFORD, JOHN and A.STANFORD, CYNTHIA and DOWLATI, YAHYA}, title = {VACCINES CONTAINING MYCOBACTERIUM VACCAE AND THEIR USE IN THE CHILDREN OF LEPROSY PATIENTS IN IRAN}, abstract ={The policy of vaccinating children who live with leprosy patients, and who have responses to leprosin A of2rnrn or less, with BCG+killed Mycobacterium vaccae if they lack a BCG scar, or with killed M. vaccae alone if they have a BCG scar, has been followed over 3-4 years in two centers in Iran. Judged on the basis of skin test conversion to leprosin positivity, the policy has been highly successful. A way in which the vaccines may work is discussed, and supported by differences in apparent efficacy between the two study centers.}, Keywords = {}, volume = {8}, Number = {2}, pages = {87-91}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1384-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1384-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {KESHAVARZ-VALIAN, HOSSEIN and JANGHORBANI, MOHSEN}, title = {THE EFFICIENCY OF A MALARIA SCREENING PROGRAM AMONG AFGHAN REFUGEES IN KERMAN, ISLAMIC REPUBLIC OF IRAN}, abstract ={Evaluation of a malaria screening program was carried out in two screened Afghan refugee camps in Bardsir and Rafsanjan and compared to non-screened Afghan refugees within Kerman, as well as refugees with malaria diagnosed by Communicable Disease Control (CDC) Laboratories in Kennan and Rafsanjan, by parasitological blood examinations. The study involved 456 residents of two refugee camps and random samples of 512 refugees in the Kerman Bus Tenninal and 1300 persons referred to Kerman and Rafsanjan CDC laboratories, aged from 1 to 70 years. Malaria was found in 403 (l7.H%) of the persons examined. Plasmodium vivax was identified in XS.I %, Plasmodiumfalciparum in 13.6% and mixed infection due to both of these species was found in 1.3% of the cases. The prevalence of parasitemia in screened camps was 4 times lower than non-screened active cases detected. A comparison of age-specific rates of malaria in screened and non-screened Afghan refugees indicated that screening programs are highly effective. The Afghan refugees bring high infection loads with them from outside and cause an out break of the infection, particularly in areas of [ran where malaria is under control. Therefore, malaria control in Afghan refugees in Iran should be primarily based on curative as well as preventive measures.}, Keywords = {Malaria, screening. Afghan refugees, Iran.}, volume = {8}, Number = {2}, pages = {81-85}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1383-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1383-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {AZARM, TALEB}, title = {SALVAGE CHEMO THERAPY WITH CYCLOPHOSPHAMIDE, DOXORUBICIN, AND CISPLATIN (CAP) IN ADVANCED BREAST CANCER}, abstract ={Twenty-one patients with advanced breast cancer (7 premenopausal and 14 postmenopausal women) were treated with a combination of cyclophosphamide, doxorubicin, and cisplatin (CAP). The median age of the patients was 43 years (range 36-61). This therapy was repeated every 3 weeks. Nine patients (group 1) received CAP as primary therapy for metastatic breast cancer, and twelve patients (group 2) received CAP as a second-line therapeutic agent. Of the 12 (57%) patients who responded, six (29%) had complete response (CR). The median disease-free survival (DFS) was 8 months. The response rate was highest for metastases in the pleura (83%) and lymph nodes (81 %), followed by skin (64%), liver and breast (55%). The overall response rate was higher in previously untreated patients than in those previously treated (89% versus 33%, p<O.O I). Complete response rates of 44% and 17%, and median DFS of 10.5 and 3 months respectively, were observed in the two groups of patients. The therapy was well tolerated, myelosuppression being the doselimiting toxicity. The most frequent nonhematological toxicities were nausea, vomiting (100%), mucositis and stomatitis (38%), but these were rarely severe. Total alopecia occurred in only two patients. There were no toxic deaths or cardiotoxicity. Severe anemia occurred more frequently in group 2 patients. The present study suggests a role for CAP combination chemotherapy in the management of advanced breast cancer.}, Keywords = {Breast cancer, combination chemotherapy,CAP regimen.}, volume = {8}, Number = {2}, pages = {75-80}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1382-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1382-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {FARHADI, M and DANESHI, A and IMAMJOMEH, H}, title = {COCHLEAR IMPLANTATION IN IRAN}, abstract ={Cochlear implantation has become an increasingly common procedure in the rehabilitation of selected cases of profound deafness.' Patients should have profound total bilateral sensorineural hearing loss. Sound is transformed into small electric currents which stimulate the auditory nerves in the cochlea and generate the hearing sensation. The nucleus cochlear implant is the result of more than 20 years of research and development and has been used in more than 9000 patients worldwide to date.' After two years of research in order to provide the cochlear implant in the Farsi (Persian) language, three out of 54 post lingual totally deaf patients up to now have undergone the cochlear implant operation with a 22-channel mini-system through a Lehnhardt incision, mastoidectomy, facial recess, and cochleostomy procedure.3-4 One month following the implant, these patients were undergoing speech education and auditory training by using innovative rehabilitation techniques for deaf people in the Persian language. This report deals with presenting three cases implanted by a cochlear implantation team in [ran and the results of rehabilitation following implant.}, Keywords = {}, volume = {8}, Number = {2}, pages = {71-74}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1381-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1381-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {BASTANI, BAHAR}, title = {MANAGEMENT OF SEVERE HYPERKALEMIA}, abstract ={}, Keywords = {}, volume = {8}, Number = {1}, pages = {65-70}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1409-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1409-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {HASHEMI, MOHAMMAD J. and PETROSSIANS, ALI ANDON}, title = {DIFFUSE ARTER IAL ECTASIA IN MARFAN SYNDROME}, abstract ={A 22 year old male referred with palpitation. General appearance and physical exam impressed us in that the patient has Marfan syndrome. Cardiac catheterization showed diffuse arterial ectasia. We found no previous report of this generalized diffuse ectasia.}, Keywords = {}, volume = {8}, Number = {1}, pages = {63-64}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1408-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1408-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {SEYYEDIALAVI, O and FATTAHlMAASOOM, SH}, title = {KRUKENBERG TUMOR REPORT OF THREE CASES}, abstract ={Krukenberg tumor is an interesting and rare tumor which usually but not always is metastatic. Ovaries more than any other genital pelvic organs are the site of metastasis. Endometrium, gastrointestinal tract and breast are the most common primary sites. The best method of treatment is surgery. Postoperatively, radiotherapy and chemotherapy must be performed. 3 cases of Krukenberg tumor diagnosed during five years are reported from Ghaem Hospital, Mashhad University of Medical Sciences. The patients' age ranged from 30 to 60 years. Clinical, laboratory and surgical follow-up was performed in all cases. Surgical treatment, radiotherapy, and chemotherapy were performed. Two cases were primary and one was secondary. Two to three years after surgery the patients returned for follow-up. AU were in good general health.}, Keywords = {}, volume = {8}, Number = {1}, pages = {59-61}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1407-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1407-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {SHAMSA, ALI}, title = {TRANSITIONAL CELL CARCINOMA OF THE BLADDER IN A 17 YEAR OLD MALE}, abstract ={Epithelial tumors are rarely seen during the first two decades of life. We report a 17 year old male with primary transitional cell carcinoma (TCC) of the bladder.}, Keywords = {}, volume = {8}, Number = {1}, pages = {57-58}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1406-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1406-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {NILI, FIROUZEH}, title = {PSEUDOHYPOALDOSTERONISM: A CASE REPORT}, abstract ={A four day old female infant was admitted because of poor feeding, vomiting and jaundice. Laboratory examination showed hyperkalemia, mild hyponatremia and renal tubular acidosis type 4. Serum aldosterone and plasma renin activity were elevated but serum cortisol, 17 -hydroxyprogesterone, ACTH, 24 hour urinary 17- ketoste roid, pregnanetriol, renal function and sonogram were normal and hence pseudohypoaldosteronism type I (pHA 1) was differentiated from congenital adrenal hyperplasia (CAH) and other metabolic disorders. These abnormalities were corrected with sodium chloride supplementation.}, Keywords = {}, volume = {8}, Number = {1}, pages = {53-55}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1405-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1405-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {BOUZARI, S and VATSALA, BR and VARGHESE, A}, title = {CHA RA CTERIZATION OF VEROTOXIN-PRODUCING STRA INS OF ENTEROPATHOGENIC ESCHERICHIA COLI (EPEC) FROM CHILDREN WITH DIA RRHOEA: EFFECTS OF THE TOXIN ON RABB IT INTESTINE}, abstract ={249 enteropathogenic Escherichia coli (EPEC) strains from faecal samples of 90 children with diarrhoea were examined for verotoxin (VT) production. Polymyxin B extracts of 61 strains belonging to 9 serogroups from 35 children produced various verotoxins (VTs). The titre of these various VTs ranged from I :40 to I: 12HO. Of the 26 (43.6%) adherent strains, 19 (73%) exhibited localized adherence (LA) and 7 (27%) manifested enteroadherent-aggregative (EA-Agg) patterns. The remaining 35 strains were nonadherent. Verotoxin producing EPECs elicited diverse effects on rabbit intestine ranging from no effect to severe damage to epithelial architecture, irrespective of their adherence patterns of HEp-2 cells. In conclusion, as far as EPEC pathogenesis is concerned, the role of verotoxins could not be established, but strains producing moderate to high levels of verotoxins may have an increased pathogenicity over non-producers.}, Keywords = {Verotoxins. Enterotoxins, EPEC, HEp-2,}, volume = {8}, Number = {1}, pages = {47-51}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1404-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1404-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {DEHGHANI, GHOLAM A. and BAHAEDINI, A}, title = {HY POXIA AND I TS INFLUEN CES ON THE CARDIOVASCULAR AND RESPIRATORY SYSTEMS OF SPONTANEOUSLY BREATHING CATS}, abstract ={Effects of acute systemic hypoxia on the cardiovascular system (CYS) and respiration of spontaneously breathing cats were studied in two conditions. 1): Hypoxic air (6-8% 02 in N2) was given to the animal to induce systemic hypoxia for 20 minutes. Hyperventilation at this condition lowered arterial C02 tension (PaC02 hypocapnia). 2): In the second run, induction of hypocapnia was prevented by adding 3-5% C02 to hypoxic air. Comparison of the results of this study indicated that hypoxia, independent of the presence of hypocapnia, caused a significant increase in respiratory rate, aortic flow and arterial blood pressure. However, in the presence of hypocapnia, the increased respiratory rate was 10% less and a general arterial vasconstriction was observed.}, Keywords = {hypocapnia; arterial chemoreceptors; cardiovascular system.}, volume = {8}, Number = {1}, pages = {43-46}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1403-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1403-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {TOTONCHI, A and RASAEE, MJ and ALLAMEH, AA and ASSADIKARAM, GR and MESBAH, SA}, title = {DEVELOPMENT OF A RAPID AND SENSITIVE RADIOIMMUNOASSAY FOR MEASUREMENT OF AFLATOXIN B 1 IN BIOLOGICAL SAMPLES}, abstract ={Aflatoxin B I (AFB) isa well known hepatocarcinogen in several animal species and probably a causative agent in human hepatocellular carcinoma. Humans are exposed to AFB by ingesting contaminated food. Aflatoxin contamination encountered in human foods is usually at low levels which is difficult to measure by chromatographic methods. Therefore in the present study we have developed an immunoassay for APB detection which is specific, sensitive and reliable. This method is applicable to a variety of biological samples such as food products, serum, milk, urine, etc. The antibody produced against AFB-bovine serum a1bwnin is highly specific with a low cross reactivity towards structurally-related aflatoxins. Other characteristics of this method including assay validation, reproducibility. recovery and statistical validations are discussed. We suggest the use of this technique as a routine method for screening food products designated for human consumption.}, Keywords = {}, volume = {8}, Number = {1}, pages = {35-41}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1402-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1402-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {SEMNANlAN, S and DASHTI, M}, title = {THE EFFECT OF LOCUS CERULEUS LESIONING ON TONIC AND PHASIC PAIN}, abstract ={Bulbospinal noradrenergic pathways are shown to have an important role in descending inhibition of pain sensation. Locus ceruleus (LC), as a rich noradrenergic nucleus in the brain stem which has projections into the dorsal horn of the spinal cord, was evaluated for antinociceptive activity by using tonic and phasic pain models in the rat. LC-lesioned rats demonstrated moderate increase in both phases of the formalin test, but did not show any effect to thermal noxious stimuli, applied in the tail-flick test. These results indicate the relative involvement of LC in inhibition of tonic, but not phasic, pain.}, Keywords = {Locus Ceruleus, Formalin, Nociception, Tail flick, Norepinephrine, Tonic pain, Phasic pain.}, volume = {8}, Number = {1}, pages = {31-34}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1401-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1401-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {ZARE, MA and SHAHRIARI, HA}, title = {FOLLOW UP OF ONE HUNDRED CORNEAL AND SCLERAL RUPTURES DURING 1988-1990}, abstract ={In a retrospective study, one hundred corneosclerallaceration (CSL) cases were managed at Zahedan Ophthalmic Center from 1988-1990. Our findings showed that CSL is more commonly seen in young and male patients. Seasonal variation in CSL frequency with higher prevalence in the fust half of the years was evident. Also it was found that cataract was more common in corneal lacerations while hyphema was more common in corneosclerallacerations.}, Keywords = {}, volume = {8}, Number = {1}, pages = {27-30}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1400-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1400-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {OMRANI, GHR and KUMAR, PY and TABEI, S and KHODDAMI, M}, title = {FNA STUDY OF 377 THYROID NODULES: A CYTOAND HISTOPATHOLOGIC CORRELATIVE STUDY}, abstract ={377 patients with single thyroid nodule who clinically were candidates for surgery, were selected from the patients that referred to the clinics of endocrinology at Namazee Hospital, Shiraz Medical School. Fine needle aspiration (FNA) was carried out without performing thyroid scan and the results were compared with histology obtained by surgery to establish its accuracy in our center. which is an area of endemic goiter. 72% were benign confirmed by surgery, 17% malignant(of which two cases were colloid goiter) and II % (42 cases) were suspicious: of these 42 suspicious cases, 28.5% were follicular carcinoma and the rest were benign. In this study sensitivity and specificity of FNA were 91 % and 97%, respectively. In conclusion, although our area is an endemic goiter area, the accuracy of FNA is comparable to iodine sufficient areas.}, Keywords = {Thyroid nodule, FNA}, volume = {8}, Number = {1}, pages = {23-25}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1399-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1399-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {HOGHOOGHI-RAD, NASSER}, title = {SOME EPIDEMIOLOGICAL ASPECTS OF CRYPTOSPORIDIOSIS IN AHWAZ, CAPITAL OF KHOOZESTAN PROVINCE, ISLAMIC REPUBLIC OF IRAN}, abstract ={From December 1990 to June 1992 in Ahwaz, capital of Khoozestan province, 1333 patients referred to Khoozestan Parasitology Center, in 29 cases of whom Cryptosporidium pallium was detected. All infected patients were less than eight years of age. The parasite was most prevalent in the 0-1 year old age group. Though some C. parVlIl1l infected cases harboured Giardia lamblia, there was no relationship between the two infections. Similarly, there was no relationship with Blastocystis hominis either. Females (l9!2Y) were significantly more commonly infected than males (10/29). The majority of cases (19/29) were detected from October to April when the weather 70%. However, no infected case was found during August and September, when the weather temperature was above 45°C and humidity was below 30%. Only 2 out of 29 were in direct contact with cattle and sheep. It is probable that the consumption of contaminated drinking tap-water was the main factor of cryptosporidium oocyst dissemination in this area.}, Keywords = {Cryptosporidilum parvum, cryptosporidiosis. giardiasis, age-groups.}, volume = {8}, Number = {1}, pages = {17-22}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1398-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1398-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {AZARM, TALEB}, title = {AUTOLOGOUS MARROW TRANSPLANTATION IN THE TREATMENT OF MOPP AND ABVD-RESI STANT HODGKIN\'S DISEASE}, abstract ={Six patients with disseminated Hodgkin's disease resistant to MOPP (mechlorethamine, vincristine, procarbazine and prednisolone), and ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) chemotherapy were treated with high-dose chemotherapy and autologous marrow transplantation. The patients first underwent marrow aspiration and storage for subsequent autologous bone marrow transplantation (AB MT). Three patients remain alive in unmaintained complete remission (CR) at I X, 17, and 15 months after transplant. In the other three patients, reasons for faiJure included relapse in two patients after 7 and g months, and death after 6 months due to pulmonary infection (pneumonia). These results demonstrate that some patients with MOPP, ABVD and other salvage chemotherapy (SC)-resistant Hodgkin's disease can obtain prolonged complete remission following intensive chemotherapy and autologous marrow transplantation}, Keywords = {Autologous marrow transplantation, Hodgkin\'s disease.}, volume = {8}, Number = {1}, pages = {9-16}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1397-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1397-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {IRAVANLOO, GUITY and ZAREMEHRIARDI, ALI}, title = {PERIPHERAL NEUROEPITHELIOMA: A STUDY OF EIGHT CASES}, abstract ={Peripheral neuroepitbelioma (PN) is a rare highly malignant tumor, classified in the group of small round cell tumors. We report eight cases of PN, based on histologic appearance and immunohistochemical staining for neuron-specific enolase (NSE). Electron microscopy was also performed in three cases. The tumors exhibited rapid local growth, leading to limb amputation in five cases. Histologically the presence of Homer-Wright rosettes is a characteristic of this neoplasm. Tumoral cells are generally positive for NSE. The relationship ofPN with Ewing's sarcoma is discussed.}, Keywords = {}, volume = {8}, Number = {1}, pages = {5-8}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1396-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1396-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} } @article{ author = {MIRDAMADI, SAEED and MOAZAMI, NASRIN and RAFIEETEHRANI, SHAHNAZ}, title = {RATE OF LISTERIA ABORTION IN TEHRAN}, abstract ={The rate of listeria abortion in Tehran was investigated. Abortion samples (200) were cold enriched at 4°C and subcultured on selective culture media containing acriflavin, nalidixic acid and potassium thiocyanate. Sera of patients were tested serologically (IF method) for screening, and results were confirmed by culturing the positive samples. Antibody against L. mollocytogelles was obtained in 70.7% of sera but the bacteria was isolated from five samples only.}, Keywords = {}, volume = {8}, Number = {1}, pages = {1-4}, publisher = {Iran University of Medical Sciences}, title_fa = {}, abstract_fa ={}, keywords_fa = {}, url = {http://mjiri.iums.ac.ir/article-1-1395-en.html}, eprint = {http://mjiri.iums.ac.ir/article-1-1395-en.pdf}, journal = {Medical Journal of The Islamic Republic of Iran (MJIRI)}, issn = {1016-1430}, eissn = {2251-6840}, year = {1994} }